Clinical and immunological aspects of recurrent, bacterial and viral skin affections

The authors analyzed the subpopulation composition of lymphocytes in the peripheral blood of 69 patients suffering from chronic recurrent furunculosis and herpes at the stage of remission. They revealed similar changes in the form of an increased content of T-helpers and immunoregulatory index. In herpes patients such changes are accompanied with the reduced number of natural killers while in furunculosis patients changes are related to the reduced amount of activated T-lymphocytes. These changes do not depend on the relapse duration or frequency but are related to the number of exacerbations in the course of the disease.

herpes, furunculosis, immunophenotyping, lymphocyte subpopulation