Vol 86, No 3 (2010)

Revisited improvement of specialized medical aid for patients with malignantcutaneous lymphomas
 
Abstract
The authors analyzed the responses from directors of dermatovenerology institutions to a standardized questionnaire with questions about recording patients with malignant cutaneous lymphomas, follow-up care, diagnostics, treatment of patients, cooperation with experts in allied fields. They also revealed defects and problems in the organization of specialized medical aid for patients with malignant cutaneous lymphomas in the territory of the Russian Federation, and developed prospective methods for improvement of aid rendered to patients with malignant cutaneous lymphomas.
Vestnik dermatologii i venerologii. 2010;86(3):4-11
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Methods for typing std pathogens (N. Gonorrhoeae, C. Trachomatis, T. Pallidum)
 
Abstract
Phenotypic methods were initially used for bacterial typing yet they have a number of drawbacks limiting their use. Methods of molecular and genetic typing have become wide-spread today. Among these methods, bacterial typing based on multilocus sequence typing (Multilocus Sequence Typing - MLST) has been developing at the fastest rate. However, schemes of molecular and genetic typing of STD pathogens as compared to other bacteria are insufficiently developed, which considerably complicates the planning of measures aimed at the reduction of their spread.
Vestnik dermatologii i venerologii. 2010;86(3):12-21
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Internet as a source of information on sexual and reproductive healthfor teenagers
 
Abstract
The article presents the results of Russian and foreign studies on using the Internet as an information source for teenagers about sexually transmitted infections. The possibility to revive the primary prevention system to fight sexually transmitted infections has been discussed, and quality criteria for present-day medical resources have been examined.
Vestnik dermatologii i venerologii. 2010;86(3):22-26
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Currentaspects of psoriasis phototherapy
 
Abstract
The review covers current aspects of ultraviolet therapy for patients suffering from psoriasis. It describes mechanisms of action as well as early and remote side effects of the current phototherapy methods. The review also presents data from literature about the risk of their cancerogenicity. It also discusses approaches to the optimization of phototherapy in view of risks and benefits for the patient.
Vestnik dermatologii i venerologii. 2010;86(3):27-32
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Results of an experimental study of the UV radiation effect on the photosensitive skin protein
 
Abstract
TsPO (18 kDa translocator protein) is a photosensitive protein regulating processes of skin proliferation and apoptosis. Changes in the conformational properties of TsPO correlate with the intensity of cell proliferation. Changes in the TsPO level in the ratsskin after exposure to UV radiation were assessed with the use of immunohistochemical staining. It was revealed that the dose of 200 J/m2 causes a unidirectional increase in the TsPO and PCNA (a cell proliferation marker) levels in the skin. UV radiation in the doses of 400-600 J/m2 induces a reduction of TsPO and PCNA expression. Thus, there is a possibility that TsPO participates in the regulation of changes in the intensity of cell proliferation in the skin under the exposure to UV radiation.
Vestnik dermatologii i venerologii. 2010;86(3):33-36
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Automated assessment of spinal fluid examination results in passivehemagglutination reaction in neurosyphilis diagnostics
 
Abstract
Spinal fluid samples collected from 50 patients suffering from neurosyphilis (key group) and 30 patients with a nervous system pathology and craniocerebral injuries without any signs of syphilis in the anamnesis (control group) were examined in the course of regulated serological tests to reveal anti-T. pallidum antibodies (complement-fixation test with a treponemal antigen, complementfixation test with a cardiolipin antigen, immunofluorescence test with whole spinal fluid, ELISA) as well as in the course of TPHA with the use of modified methods with the end-point dilution of spinal fluid as 1:4. Visual assessment was used to assess the TPHA results with the determination of the result positivity degree expressed in conditional units - «pluses», along with the automated assessment using the Criterion 2 hardware system. Comparative results of visual and instrumental assessments of the spinal fluid study results in TPHA revealed full compliance of the qualitative study results and 97.5% correspondence in the results expressed in conditional units («pluses»), which provides sufficient grounds for recommending the Criterion 2 automatic diagnostics complex for TPHA image assessment to be used in clinical and diagnostic laboratories in health care institutions for determining treponemal specific antibodies in spinal fluid for neurosyphilis diagnostics.
Vestnik dermatologii i venerologii. 2010;86(3):37-42
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Clinical efficacy of the microwave therapy for infectious and inflammatorydiseases of the urogenital system
 
Abstract
The article describes complex treatment of 56 patients suffering from with chronic prostatitis and vesiculitis with the use of microwave irradiation (of the cm range). This complex therapy made it possible to achieve better results in the main group of patients vs. the comparison group (71 people), who received only drug treatment. Treatment resulted in the normalization of the leukocyte count in the prostate gland discharge and venous circulation rate in the prostatic plexus. A reduction in the diameter of the venous lumen was observed in more cases in the group of patients undergoing a microwave therapy than in the comparison group.
Vestnik dermatologii i venerologii. 2010;86(3):43-45
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About the issue of clinical recommendations of the Russian Association of Dermatologists and Venereologists Dermatology 2008 (Part 1 - Syphilis)
 
Abstract
The article is written in the form of a discussion. It examis. The described provisions are assessed in a positive way, and the authors suggest introducing certain changes and amendments based on the authors' own studies.ines the clinical recommendations regarding syphilis being the forerunner of the publication entitled Guidelines for Patient Management. Syphil
Vestnik dermatologii i venerologii. 2010;86(3):46-48
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Assessment of the efficacy of a new zinc pyrithione drug, Cinocap®, for treatment of patients with seborrheic dermatitis
 
Abstract
The goal of this study was to assess the efficacy and safety of a zinc pyrithione drug, Cinocap® aerosol, and assess its therapeutic equivalence to the original drug, Skin-Cap® aerosol, in patients with seborrheic dermatitis. Study design: prospective, open-label, randomized comparative clinical study. Patients (40) aged 18-65 were randomized into two statistically comparable groups. Patients from the first group received a monotherapy with Cinocap® aerosol for 14 days while patients from the second group were treated with Skin-Cap® aerosol. Based on the data obtained in the course of the study, it was proved that Cinocap® is an efficient drug for treatment of seborrheic dermatitis and is comparable to the original drug, Skin-Cap®, by its therapeutic effect and safety.
Vestnik dermatologii i venerologii. 2010;86(3):49-55
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Using Heptral® (Ademetionine) to treat hepatic affections in leprosy patients
 
Abstract
The article is devoted to the problem of chronic hepatic diseases in leprosy patients at the stage of long-term rehabilitation. The article focuses on the opportunity to use such hepatoprotector as Heptral® for the complex treatment of chronic hepatic affections in leprosy patients, and presents the authors' clinical experience of studying the drug efficacy.
Vestnik dermatologii i venerologii. 2010;86(3):57-60
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Current approach to improving balanoposthitis therapy
 
Abstract
Widespread occurrence of balanoposthitis results in the need to develop highly efficient treatment methods. The activity of clinical manifestations of the disease is directly related to the condition of local immunity and opportunistic flora as well as presence of a viral infection. Application of the Epigen Intim spray having anti-inflammatory, wound-healing, antiviral and immunomodulatory properties for treatment of irritant balanoposthitis proved to be efficient in 90% of the study subjects. The drug therapy reduced the duration of disease manifestations and increased the remission term. The suggested treatment method optimizes treatment of balanoposthitis.
Vestnik dermatologii i venerologii. 2010;86(3):61-65
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Modern approaches to the classification of topical glucocorticosteroidsin Russia and abroad
 
Abstract
The article analyzes current classifications of topical glucocorticosteroid drugs. It also describes advantages and disadvantages of current classifications, emphasizes the expediency of assessing not only the efficacy of the active ingredient but also its skin concentration taking into consideration the base, trade name of the drug and particular features of its biotransformation in the skin.
Vestnik dermatologii i venerologii. 2010;86(3):67-69
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Binafin in treatment of nail mycosis
 
Abstract
The article presents the results of a direct open-label study of the efficacy and safety of BINAFIN® for treatment of foot and hand nail mycoses in 30 patients. Patients were administered one pill (250 mg) of BINAFIN® a day on a daily basis for 3-5 months. Clinical and anti-mycosis efficacy was achieved in 92.6% cases of foot and hand nail mycoses.
Vestnik dermatologii i venerologii. 2010;86(3):70-74
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About local administration of antibacterial drugs for acne therapy
 
Abstract
The review summarizes and systematizes data accumulated in the world research literature, which are related to the role of P. acnes in the pathogenesis of acne, its microbiology and antibacterial resistance; it also examines antibacterial drugs for the external therapy of acne and recommendations for their use.
Vestnik dermatologii i venerologii. 2010;86(3):75-85
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A case study of acrokeratosis paraneoplastica (Bazex syndrome)
 
Abstract
This article presents data about the etiology, pathogenesis, clinical course and methods of treatment for a rare obligate paraneoplastic dermatosis - the Bazex syndrome. The authors share their own observations.
Vestnik dermatologii i venerologii. 2010;86(3):87-89
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Linear dermatosis developed in infants against the background of allergicdiseases: a clinical study
 
Abstract
The article presents a clinical study of two cases when linear unilateral dermatosis developed in children suffering from allergic diseases: against the background of atopic dermatitis and obstructive bronchitis with signs of transformation into bronchial asthma.
Vestnik dermatologii i venerologii. 2010;86(3):90-93
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Functional condition of the lip skin: effect of the age and hormone replacementtherapy
 
Abstract
Goal: To assess the effect of the age and hormone replacement therapy (HRT) on the functional properties of the lip skin in women. Materials and methods: The author conducted a comparative study of the functional properties of lips in 4 groups (young women at the age of 20-34 and 40-49 with regular menstrual cycles, two groups of post-menopausal women taking and not taking HRT). The following was assessed: degree of skin oiliness on the forehead, on the lower lip - transepidermal waster loss (TEWL), mechanical deformation and elasticity, color, tactile sensitivity, hydration. Results: Changes in the TEWL, mechanical deformation and tactile sensitivity are age-related while a more saturated color of the lips may be caused by HRT. Skin oiliness is also related to the hormonal profile in women. No effect of the age or hormonal status on the moisture content in the lips was revealed. The study confirmed that the upper lip has a greater moisture content than the lower one. Conclusion: The study revealed a hormonal effect on the skin fat secretion, which reduces during the post-menopausal period and is stimulated by hormone replacement therapy. Age-related changes in the elasticity and tactile sensitivity of the vermilion border are similar to those in skin parameters.
Vestnik dermatologii i venerologii. 2010;86(3):94-99
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K 55 letiyuS.G. Mardanly prezidenta ZAO «EKOlab»
 
Abstract
Vestnik dermatologii i venerologii. 2010;86(3):100-101
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Pozdravlyaem pobediteley vserossiyskogokonkursa«Luchshiy vrach goda -2010»
 
Abstract
Vestnik dermatologii i venerologii. 2010;86(3):102-103
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