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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Vestnik dermatologii i venerologii</journal-id><journal-title-group><journal-title xml:lang="en">Vestnik dermatologii i venerologii</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник дерматологии и венерологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0042-4609</issn><issn publication-format="electronic">2313-6294</issn><publisher><publisher-name xml:lang="en">Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1139</article-id><article-id pub-id-type="doi">10.25208/vdv1139</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL CASE REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЕ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Hoffman's Recalcitrant Dissecting Folliculitis — State of the Problem, Approach to Therapy, Demonstration of Clinical Cases</article-title><trans-title-group xml:lang="ru"><trans-title>Подрывающий фолликулит Гоффмана — состояние проблемы, подходы к терапии, демонстрация клинических случаев</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7689-8350</contrib-id><name-alternatives><name xml:lang="en"><surname>Drozhdina</surname><given-names>Marianna B.</given-names></name><name xml:lang="ru"><surname>Дрождина</surname><given-names>Марианна Борисовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Professor, PhD, MD, Professor of the department od dermatovenereology and cosmetology</p></bio><bio xml:lang="ru"><p>Доцент, кандидат медицинских наук, доцент кафедры дерматовенерологии и косметологии</p></bio><email>drozhdina@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2306-1423</contrib-id><name-alternatives><name xml:lang="en"><surname>Bobro</surname><given-names>Varvara A.</given-names></name><name xml:lang="ru"><surname>Бобро</surname><given-names>Варвара Андреевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dermatovenerologist</p></bio><bio xml:lang="ru"><p>врач-дерматовенеролог</p></bio><email>bobro.va@inbox.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">FBSEI HE Kirov State Medical University of the Ministry of Health of Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Кировский ГМУ» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Kirov Regional State Budgetary Healthcare Institution Kirov Regional Clinical Dermatovenereologic Hospital&#13;
Semashko</institution></aff><aff><institution xml:lang="ru">КОГБУЗ КОККВД</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-08-02" publication-format="electronic"><day>02</day><month>08</month><year>2020</year></pub-date><volume>96</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>35</fpage><lpage>43</lpage><history><date date-type="received" iso-8601-date="2020-05-22"><day>22</day><month>05</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-06-03"><day>03</day><month>06</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Drozhdina M.B., Bobro V.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, Дрождина М.Б., Бобро В.А.</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Drozhdina M.B., Bobro V.A.</copyright-holder><copyright-holder xml:lang="ru">Дрождина М.Б., Бобро В.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikdv.ru/jour/article/view/1139">https://vestnikdv.ru/jour/article/view/1139</self-uri><abstract xml:lang="en"><p>A review of the literature on the etiology, pathogenesis, and evidence base of therapeutic approaches for the management of patients with Hoffman's recalcitrant dissecting folliculitis is presented. The article describes the clinic of the disease, complications and optimal therapeutic tactics at the present stage. Attention is focused on the problem of antibiotic resistance and ways to solve it. A clinical case with a successful therapeutic outcome is presented. The article is illustrated with photos on the patients from the author's archive.</p></abstract><trans-abstract xml:lang="ru"><p>Представлен обзор литературы по этиологии, патогенезу, доказательной базе терапевтических подходов к ведению пациентов с подрывающим фолликулитом Гоффмана. Описаны клиника заболевания, осложнения и оптимальная терапевтическая тактика на современном этапе. Заострено внимание на проблеме антибиотикорезистентности и путях ее решения. Представлен клинический случай с успешным терапевтическим исходом. Статья иллюстрирована фотографиями по теме из архива автора.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Hoffman's recalcitrant dissecting folliculitis</kwd><kwd>follicular occlusal triad</kwd><kwd>Cutibacterium acnes</kwd><kwd>alopecia</kwd><kwd>antibiotic resistance</kwd><kwd>systemic isotretinoin</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>подрывающий фолликулит Гоффмана</kwd><kwd>фолликулярная окклюзионная триада</kwd><kwd>Cutibacterium acnes</kwd><kwd>алопеция</kwd><kwd>антибиотикорезистентность</kwd><kwd>системный изотретиноин</kwd></kwd-group><funding-group><funding-statement xml:lang="en">Jadran</funding-statement><funding-statement xml:lang="ru">ООО "ЯДРАН"</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Luderschmidt C., Klövekorn W. Systemic inflammatory reactions and extracutaneous manifestations of Acne vulgaris. 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