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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Vestnik dermatologii i venerologii</journal-id><journal-title-group><journal-title xml:lang="en">Vestnik dermatologii i venerologii</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник дерматологии и венерологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0042-4609</issn><issn publication-format="electronic">2313-6294</issn><publisher><publisher-name xml:lang="en">Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1185</article-id><article-id pub-id-type="doi">10.25208/vdv1185</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Current approaches to the diagnosis of autoimmune bullous dermatoses</article-title><trans-title-group xml:lang="ru"><trans-title>Актуальные подходы к диагностике аутоиммунных пузырных дерматозов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7689-8350</contrib-id><contrib-id contrib-id-type="spin">6938-4768</contrib-id><name-alternatives><name xml:lang="en"><surname>Drozhdina</surname><given-names>Marianna B.</given-names></name><name xml:lang="ru"><surname>Дрождина</surname><given-names>Марианна Борисовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>assistant professor</p></bio><bio xml:lang="ru"><p>доцент</p></bio><email>drozhdina@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2306-1423</contrib-id><contrib-id contrib-id-type="spin">2534-4480</contrib-id><name-alternatives><name xml:lang="en"><surname>Bobro</surname><given-names>Varvara A.</given-names></name><name xml:lang="ru"><surname>Бобро</surname><given-names>Варвара Андреевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>postgraduate student</p></bio><bio xml:lang="ru"><p>аспирант</p></bio><email>bobro.va@inbox.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5484-778X</contrib-id><name-alternatives><name xml:lang="en"><surname>Sennikova</surname><given-names>Yuliana A.</given-names></name><name xml:lang="ru"><surname>Сенникова</surname><given-names>Юлиана Алексеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>student</p></bio><bio xml:lang="ru"><p>студент</p></bio><email>sennikova.yuliana@inbox.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kirov State Medical Academy</institution></aff><aff><institution xml:lang="ru">Кировский государственный медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-03-24" publication-format="electronic"><day>24</day><month>03</month><year>2021</year></pub-date><volume>97</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>16</fpage><lpage>26</lpage><history><date date-type="received" iso-8601-date="2020-10-31"><day>31</day><month>10</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2021-02-09"><day>09</day><month>02</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Drozhdina M.B., Bobro V.A., Sennikova Y.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, Дрождина М.Б., Бобро В.А., Сенникова Ю.А.</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Drozhdina M.B., Bobro V.A., Sennikova Y.A.</copyright-holder><copyright-holder xml:lang="ru">Дрождина М.Б., Бобро В.А., Сенникова Ю.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikdv.ru/jour/article/view/1185">https://vestnikdv.ru/jour/article/view/1185</self-uri><abstract xml:lang="en"><p>A modern review of highly effective methods for the diagnosis of autoimmune bullous dermatoses are presented. The specificity of the production of autoantibodies underlying bullous dermatoses are described. Considering the severity of the disease and a significant deterioration in the quality of life of patients suffering from bullous dermatoses; the systematization of diagnostic criteria will help improve the prognosis and management of patients; and it will also help optimize work on the development of targeted drugs for the treatment of patients with this pathology.</p></abstract><trans-abstract xml:lang="ru"><p>Представлен обзор высокоэффективных методов диагностики аутоиммунных пузырных дерматозов. Описана специфика выработки аутоантител; лежащих в основе патогенеза пузырных дерматозов. Учитывая тяжесть течения заболеваний и значительное ухудшение качества жизни пациентов; страдающих пузырными дерматозами; систематизирование диагностических критериев поможет улучшить прогнозирование и тактику ведения пациентов; а также оптимизировать работу по разработке таргетных препаратов для лечения пациентов с данной патологией.</p></trans-abstract><kwd-group xml:lang="en"><kwd>pemphigus</kwd><kwd>pemphigoid</kwd><kwd>desmoglein</kwd><kwd>desmocollin</kwd><kwd>pectin</kwd><kwd>BP180</kwd><kwd>BP230</kwd><kwd>collagen type VII</kwd><kwd>laminin</kwd><kwd>deamidated gliadin</kwd><kwd>tissue transglutaminase</kwd><kwd>antigenic epitopes</kwd><kwd>BIOCHIP</kwd><kwd>multivariate ELISA</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>пузырчатка</kwd><kwd>пемфигоид</kwd><kwd>десмоглеин</kwd><kwd>десмоколлин</kwd><kwd>плектин</kwd><kwd>BP180</kwd><kwd>BP230</kwd><kwd>тип VII коллагена</kwd><kwd>ламинин</kwd><kwd>деамидированный глиадин</kwd><kwd>тканевая трансглутаминаза</kwd><kwd>антигенные эпитопы</kwd><kwd>BIOCHIP</kwd><kwd>многопараметрический иммуноферментный анализ</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Kasperkiewicz M; Ellebrecht CT; Takahashi H; et al. 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