Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov12310.25208/0042-4609-2015-91-2-58-62SHORT COMMUNICATIONКРАТКИЕ СООБЩЕНИЯBiofilms of microorganisms and their role for the formation of resistance to anti-bacterial drugsБиопленки микроорганизмов и их роль в формировании резистентности к антибактериальным препаратамRakhmatulinaM. R.РахматулинаМ. Р.
Russian Federation
rahmatulina@cnikvi.ruNechayevaI. A.НечаеваИ. А.
Russian Federation
State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian FederationФГБУ «Государственный научный центр дерматовенерологии и косметологии» Минздрава России24042015912586224082017Copyright ©; 2015, Rakhmatulina M.R., Nechayeva I.A.Copyright ©; 2015, Рахматулина М.Р., Нечаева И.А.2015Rakhmatulina M.R., Nechayeva I.A.Рахматулина М.Р., Нечаева И.А.https://creativecommons.org/licenses/by/4.0https://vestnikdv.ru/jour/article/view/123

The article describes current concepts of mechanisms of the formation of biofilms - a supracellular colonial prokaryotic form of microorganisms causing infectious urogenital pathologies. The authors describe the role of signal molecules and extracellular genetic material for the biofilm formation as well as synergy and antagonism between different types of bacteria. The article presents possible mechanisms of existence of prokaryotes causing torpidity to the therapy and resulting in a longterm chronic infection.

Изложены современные представления о механизмах формирования биопленок - надклеточной колониальнопрокариотической формы микроорганизмов, вызывающих инфекционную урогенитальную патологию. Описана роль сигнальных молекул и экстрацеллюлярного генетического материала в формировании биопленок, а также синергические и антагонистические взаимоотношения между разными видами бактерий. Представлены возможные механизмы существования прокариот, обусловливающие торпидность к проводимой терапии и приводящие к длительному хроническому течению инфекционного процесса.

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