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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Vestnik dermatologii i venerologii</journal-id><journal-title-group><journal-title xml:lang="en">Vestnik dermatologii i venerologii</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник дерматологии и венерологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0042-4609</issn><issn publication-format="electronic">2313-6294</issn><publisher><publisher-name xml:lang="en">Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">13276</article-id><article-id pub-id-type="doi">10.25208/vdv13276</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL CASE REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЕ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Difficult path to the diagnosis of chromomycosis</article-title><trans-title-group xml:lang="ru"><trans-title>Сложный путь к диагнозу «хромомикоз»</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9983-0327</contrib-id><name-alternatives><name xml:lang="en"><surname>Melnikova</surname><given-names>Tatyana V.</given-names></name><name xml:lang="ru"><surname>Мельникова</surname><given-names>Татьяна Витальевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>tatmel2007@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1800-1610</contrib-id><name-alternatives><name xml:lang="en"><surname>Burtseva</surname><given-names>Natalya Yu.</given-names></name><name xml:lang="ru"><surname>Бурцева</surname><given-names>Наталия Юрьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dermatovenereologist</p></bio><bio xml:lang="ru"><p>врач-дерматовенеролог</p></bio><email>burtsevaderm@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-1170-3232</contrib-id><name-alternatives><name xml:lang="en"><surname>Cheboksarova</surname><given-names>Tatyana A.</given-names></name><name xml:lang="ru"><surname>Чебоксарова</surname><given-names>Татьяна Алексеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>6th Year Student</p></bio><bio xml:lang="ru"><p>студентка VI курса</p></bio><email>sturovatanya@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7610-6061</contrib-id><name-alternatives><name xml:lang="en"><surname>Sokolovskiy</surname><given-names>Evgeny V.</given-names></name><name xml:lang="ru"><surname>Соколовский</surname><given-names>Евгений Владиславович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>s40@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">First Pavlov State Medical University of Saint Petersburg</institution></aff><aff><institution xml:lang="ru">Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-02-09" publication-format="electronic"><day>09</day><month>02</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2024-03-18" publication-format="electronic"><day>18</day><month>03</month><year>2024</year></pub-date><volume>100</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>85</fpage><lpage>92</lpage><history><date date-type="received" iso-8601-date="2023-06-27"><day>27</day><month>06</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2024-01-30"><day>30</day><month>01</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Melnikova T.V., Burtseva N.Y., Cheboksarova T.A., Sokolovskiy E.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Мельникова Т.В., Бурцева Н.Ю., Чебоксарова Т.А., Соколовский Е.В.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Melnikova T.V., Burtseva N.Y., Cheboksarova T.A., Sokolovskiy E.V.</copyright-holder><copyright-holder xml:lang="ru">Мельникова Т.В., Бурцева Н.Ю., Чебоксарова Т.А., Соколовский Е.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikdv.ru/jour/article/view/13276">https://vestnikdv.ru/jour/article/view/13276</self-uri><abstract xml:lang="en"><p>Chromomycosis is a slowly occurring mycosis of subcutaneous adipose tissue and skin. Most often, cases of the disease are recorded in countries with a tropical and subtropical climate. In the Russian Federation, the disease occurs sporadically. Very rarely (2 cases out of 100) malignant transformation into squamous cell carcinoma occurs. The article presents a clinical case of chromomycosis. A description is given of a patient in whom squamous cell carcinoma was detected at the onset of the disease, which was the reason for treatment by oncologists. Six months later, the patient had a relapse in the area of the postoperative scar and a focus in the area of the right hand. Repeated biopsy with histological examination made it possible to establish the correct diagnosis. Interest in the above clinical case was caused by the detection of chromomycosis in a resident of the city of Saint Petersburg, who was not in endemic areas, was not engaged in agricultural work, and denied the primary injury. Our patient experienced a rapid malignancy of the focus, after surgical treatment, a recurrence of deep mycosis occurred. A good effect was obtained from systemic antimycotic therapy.</p></abstract><trans-abstract xml:lang="ru"><p>Хромомикоз является медленно протекающим микозом подкожной жировой клетчатки и кожи. Чаще всего случаи заболевания регистрируются в странах с тропическим и субтропическим климатом. В Российской Федерации заболевание встречается спорадически. Крайне редко (2 случая из 100) происходит злокачественная трансформация в плоскоклеточный рак. В статье представлен клинический случай хромомикоза. Приведено описание пациента, у которого в дебюте заболевания был выявлен плоскоклеточный рак, что послужило причиной для лечения у онкологов. Через полгода у больного возник рецидив в зоне послеоперационного рубца и очаг в области правой кисти. Повторная биопсия с гистологическим исследованием позволила установить правильный диагноз. Интерес к приведенному клиническому случаю вызван выявлением хромомикоза у жителя г. Санкт-Петербурга, который не находился в эндемичных районах, не занимался сельскохозяйственными работами, отрицал первичную травму. У нашего пациента произошла быстрая малигнизация очага, после проведенного хирургического лечения возник рецидив глубокого микоза. Был получен хороший эффект от системной антимикотической терапии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>chromomycosis</kwd><kwd>squamous cell skin cancer</kwd><kwd>clinical case</kwd><kwd>itraconazole</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>хромомикоз</kwd><kwd>плоскоклеточный рак кожи</kwd><kwd>клинический случай</kwd><kwd>итраконазол</kwd></kwd-group><funding-group><funding-statement xml:lang="en">First Pavlov State Medical University of Saint Petersburg</funding-statement><funding-statement xml:lang="ru">Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. 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