Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov1604810.25208/vdv16048REVIEWSОБЗОР ЛИТЕРАТУРЫResearch ArticleGrover’s disease — current understanding of transient and persistent acantholytic dermatosisБолезнь Гровера: современные представления о транзиторном и персистирующем акантолитическом дерматозеhttps://orcid.org/0000-0001-6883-07625037-7208ChepushtanovaKseniya O.ЧепуштановаКсения Олеговна
Russian Federation
kseniyachepushtanova@mail.ruhttps://orcid.org/0000-0002-6989-93631367-5580PatrushevAleksandr V.ПатрушевАлександр Владимирович
Russian Federation

MD, Dr. Sci. (Med.)

д.м.н.

alexpat2@yandex.ruhttps://orcid.org/0000-0002-1375-056X3393-3256GorbunovYuri G.ГорбуновЮрий Геннадьевич
Russian Federation

MD, Cand. Sci. (Med.)

к.м.н.

urikgor@rambler.ruhttps://orcid.org/0000-0002-9458-08722287-5062BelousovaIrena E.БелоусоваИрена Эдуардовна
Russian Federation

MD, Dr. Sci. (Med.), Professor

д.м.н., профессор

irena.belousova@mail.ruS.M. Kirov Military Medical AcademyВоенно-медицинская академия имени С.М. Кирова0706202411072024100317250110202322052024Copyright ©; 2024, Chepushtanova K.O., Patrushev A.V., Gorbunov Y.G., Belousova I.E.Copyright ©; 2024, Чепуштанова К.О., Патрушев А.В., Горбунов Ю.Г., Белоусова И.Э.2024Chepushtanova K.O., Patrushev A.V., Gorbunov Y.G., Belousova I.E.Чепуштанова К.О., Патрушев А.В., Горбунов Ю.Г., Белоусова И.Э.https://creativecommons.org/licenses/by-nc/4.0https://vestnikdv.ru/jour/article/view/16048

Grover’s disease is a papulo-vesicular pruritic dermatosis characterized by a transient, persistent, or asymptomatic course. We have analyzed the publications found in the PubMed and RSCI scientific literature databases between 1970 and 2022. The clinical manifestations of Grover’s disease, possible localization, etiological factors, and the histological and dermatoscopic picture of the disease are described. According to the literature, the putative associations with disease onset are highly variable and include insolation, pregnancy, hemodialysis, chemotherapy, sweating, a number of dermatoses, and a history of malignancy and organ transplantation. Seasonality of the process has also been described. To date, nine histologic patterns of the disease have been described, the most common being acantholytic dyskeratosis.

Болезнь Гровера — папуло-везикулезный зудящий дерматоз, характеризующийся транзиторным, персистирующим или бессимптомным течением. Нами проведен анализ публикаций, обнаруженных в базах данных научной литературы PubMed и РИНЦ, с 1970 по 2022 г. Описаны клинические проявления болезни Гровера, возможная локализация, этиологические факторы, гистологическая и дерматоскопическая картины заболевания. По данным литературы, предполагаемые ассоциации с началом заболевания очень вариабельны и включают инсоляцию, беременность, гемодиализ, химиотерапию, потливость, ряд дерматозов, а также злокачественные заболевания и трансплантацию органов в анамнезе. Также указывается сезонность процесса. На данный момент описано девять гистологических паттернов заболевания, наиболее часто встречается акантолитический дискератоз.

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