Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov1679810.25208/vdv16798REVIEWSОБЗОР ЛИТЕРАТУРЫReview ArticleDermatologic aspects of onychophagiaДерматологические аспекты онихофагииhttps://orcid.org/0000-0001-9676-15815120-9250SaranyukRoman V.СаранюкРоман Владимирович
Russian Federation
roman.saranuk@gmail.comhttps://orcid.org/0000-0003-0059-9159GostevaTatyana A.ГостеваТатьяна Александровна
Russian Federation
ya-lisenok-@mail.ruKRPO “Society of Integrative Dermatology”КРОО «Общество интегративной дерматологии»Clinic of Dermatology and Venereology “Derma Expert”Кабинет дерматологии и венерологии «Derma Эксперт»Kurchatov Center for Modern MedicineКурчатовский центр современной медицины2909202422112024100532391206202413092024Copyright ©; 2024, Saranyuk R.V., Gosteva T.A.Copyright ©; 2024, Саранюк Р.В., Гостева Т.А.2024Saranyuk R.V., Gosteva T.A.Саранюк Р.В., Гостева Т.А.https://creativecommons.org/licenses/by-nc/4.0https://vestnikdv.ru/jour/article/view/16798

Onychophagia is a psychiatric disorder manifested by compulsive, repetitive biting of nail plates. To date, the etiopathogenesis of the disease remains incompletely understood. The leading role in the development of this condition is attributed to concomitant mental disorders. Nevertheless, onychophagy today is a complex interdisciplinary problem that requires the involvement of doctors of various specialties. Dermatologists are no exception. Clinical evaluation of nails in onychophagia by a dermatologist is important both in terms of diagnosis and possible ways of correcting pathologic changes in nail plates. This article provides up-to-date information on onychophagia with an emphasis on the dermatologic aspect of the disorder.

Онихофагия представляет собой психическое расстройство, выражающееся в навязчивом, повторяющемся обкусывании ногтевых пластин. На сегодняшний день этиопатогенез заболевания остается не до конца изученным. Ведущую роль в развитии данного состояния отдают сопутствующим психическим расстройствам. Тем не менее онихофагия на сегодняшний день представляет собой сложную междисциплинарную проблему, требующую привлечения врачей различных специальностей. Дерматологи не являются исключением. Клиническая оценка состояния ногтей при онихофагии со стороны дерматолога важна с точки зрения как постановки диагноза, так и возможных способов коррекции патологических изменений ногтевых пластин. В данной статье представлена актуальная информация об онихофагии с акцентом на дерматологический аспект данного расстройства.

оnychophagialamellar onychochisisventral pterygiumleukonychiaонихофагияпластинчатый (ламеллярный) онихошизисвентральный птеригумлейконихияGhanizadeh A. Nail biting; etiology, consequences and management. Iran J Med Sci. 2011;36(2):73–79.Halteh P, Scher RK, Lipner SR. Onychophagia: a nail-biting conundrum for physicians. J Dermatolog Treat. 2017;28(2):166–172. doi: 10.1080/09546634.2016.1200711Singal A, Daulatabad D. Nail tic disorders: manifestations, pathogenesis and management. Indian J Dermatol Venereol Leprol. 2017;83(1):19–26. doi: 10.4103/0378-6323.184202Winebrake JP, Grover K, Halteh P, Lipner SR. Pediatric onychophagia: a survey-based study of prevalence, etiologies, and co-morbidities. Am J Clin Dermatol. 2018;19(6):887–891. doi: 10.1007/s40257-018-0386-1Mitropoulos P, Norton SA. Dermatophagia or dermatodaxia? J Am Acad Dermatol. 2005;53(2):365. doi: 10.1016/j.jaad.2005.04.021Pacan P, Grzesiak M, Reich A, Kantorska-Janiec M, Szepietowski JC. Onychophagia and onychotillomania: Prevalence, clinical picture and comorbidities. Acta Derm Venereol. 2014;94(1):67–71. doi: 10.2340/00015555-1616Lipner SR, Scher RK. Comment on “Psychocutaneous disease: Clinical perspectives”. J Am Acad Dermatol. 2017;77(5):e141–e142. doi: 10.1016/j.jaad.2017.05.061Foster LG. Nervous habits and stereotyped behaviors in preschool children. J Am Acad Child Adolesc Psychiatry. 1998;37(7):711–717. doi: 10.1097/00004583-199807000-00010Ghanizadeh A. Association of nail biting and psychiatric disorders in children and their parents in a psychiatrically referred sample of children. Child Adolesc. Psychiatry Ment Health. 2008;2(1):13. doi: 10.1186/1753-2000-2-13Ghanizadeh A, Shekoohi H. Prevalence of nail biting and its association with mental health in a community sample of children. BMC Res Notes. 2011;4:116. doi: 10.1186/1756-0500-4-116Ooki S. Genetic and environmental influences on finger-sucking and nail-biting in Japanese twin children. Twin Res Hum Genet. 2005;8(4):320–327. doi: 10.1375/1832427054936637Erdogan HK, Arslantas D, Atay E, Eyuboglu D, Unsal A, Dagtekin G, et al. Prevalence of onychophagia and its relation to stress and quality of life. Acta Dermatovenerol Alp Pannonica Adriat. 2021;30(1):15–19.Sani G, Gualtieri I, Paolini M, Bonanni L, Spinazzola E, Maggiora M, et al. Drug Treatment of Trichotillomania (Hair-Pulling Disorder), Excoriation (Skin-picking) Disorder, and Nail-biting (Onychophagia). Curr Neuropharmacol. 2019;17(8):775–786. doi: 10.2174/1570159X17666190320164223Sachan A, Chaturvedi TP. Onychophagia (Nail biting), anxiety, and malocclusion. Indian J Dent Res. 2012;23(5):680–682. doi: 10.4103/0970-9290.107399Reddy S, Sanjai K, Kumaraswamy J, Papaiah L, Jeevan M. Oral carriage of enterobacteriaceae among school children with chronic nail-biting habit. J Oral Maxillofac Pathol. 2013;17(2):163–168. doi: 10.4103/0973-029X.119743Cohen PR. Nail-Associated Body-Focused Repetitive Behaviors: Habit-Tic Nail Deformity, Onychophagia, and Onychotillomania. Cureus 2022;14(3):e22818. doi: 10.7759/cureus.22818Tosti A, Peluso AM, Bardazzi F, Morelli R, Bassi F. Phalangeal osteomyelitis due to nail biting. Acta Derm Venereol. 1994;74(3):206–207. doi: 10.2340/0001555574206207Richert B, André J. Nail disorders in children: Diagnosis’ and management. Am J Clin Dermatol. 2011;12(2):101–112. doi: 10.2165/11537110-000000000-00000Jin H, Kim JM, Kim GW, Song M, Kim HS, Ko HC, et al. Diagnostic criteria for and clinical review of melanonychia in Korean patients. J Am Acad Dermatol. 2016;74(6):1121–1127. doi: 10.1016/j.jaad.2015.12.039Fıçıcıoğlu S, Korkmaz S. Onychophagia Induced Melanonychia, Splinter Hemorrhages, Leukonychia, and Pterygium Inversum Unguis Concurrently. Case Rep Dermatol Med. 2018;2018:3230582. doi: 10.1155/2018/3230582Shin JO, Roh D, Son JH, Shin K, Kim HS, Ko HC, et al. Onychophagia: Detailed clinical characteristics. Int J Dermatol. 2021;61(3):331–336. doi: 10.1111/ijd.15861Baghchechi M, Pelletier JL, Jacob SE. Art of Prevention: The importance of tackling the nail biting habit. Int J Womens Dermatol. 2021;7(3):309–313. doi: 10.1016/j.ijwd.2020.09.008Anolik RB, Shah K, Rubin AI. Onychophagia-induced longitudinal melanonychia. Pediatr Dermatol. 2012;29(4):488–489. doi: 10.1111/j.1525-1470.2011.01496.xLencastre A, Lamas A, Sá D, Tosti A. Onychoscopy. Clin Dermatol. 2013;31(5):587–593. doi: 10.1016/j.clindermatol.2013.06.016Canavan T, Tosti A, Mallory H, McKay K, Cantrell W, Elewski B. An Idiopathic Leukonychia Totalis and Leukonychia Partialis Case Report and Review of the Literature. Skin Appendage Disord. 2015;1(1):38–42. doi: 10.1159/000380956Cohen PR. Skin biter: dermatodaxia revisited. Cureus. 2022;14(2):e22289. doi: 10.7759/cureus.22289Chen Y, Pradhan S, Lyu L, Xue S. Clinical and dermoscopic characteristics of onychophagia and onychotillomania: a retrospective study of 63 cases. Clin Exp Dermatol. 2022;47(5):961–963. doi: 10.1111/ced.15057Stewart C, Lipner SR. Insights into recurrent body-focused repetitive behaviors: Evidenced by New York Times commenters. Arch Dermatol Res. 2020;312(9):629–634. doi: 10.1007/s00403-020-02045-6Waldman BA, Frieden IJ. Osteomyelitis caused by nail biting. Pediatr Dermatol. 1990;7(3):189–190. doi: 10.1111/j.1525-1470.1990.tb00279.xSzinnai G, Schaad UB, Heininger U. Multiple herpetic whitlow lesions in a 4-year-old girl: case report and review of the literature. Eur J Pediatr. 2001;160(9):528–533. doi: 10.1007/s004310100800Tosti A, Piraccini BM. Warts of the nail unit: Surgical and nonsurgical approaches. Dermatol Surg. 2001;27(3):235–239.Jiaravuthisan MM, Sasseville D, Vender RB, Murphy F, Muhn CY. Psoriasis of the nail: Anatomy, pathology, clinical presentation, and a review of the literature on therapy. J Am Acad Dermatol. 2007;57(1):1–27. doi: 10.1016/j.jaad.2005.07.073Goettmann S, Zaraa I, Moulonguet I. Nail lichen planus: Epidemiological, clinical, pathological, therapeutic and prognosis study of 67 cases. J Eur Acad Dermatol Venereol. 2012;26(10):1304–1309. doi: 10.1111/j.1468-3083.2011.04288.xCochran AM, Buchanan PJ, Bueno Jr RA, Neumeister MW. Subungual melanoma: A review of current treatment. Plast Reconstr Surg. 2014;134(2):259–273. doi: 10.1097/PRS.0000000000000529Haenssle HA, Blum A, Hofmann-Wellenhof R, Kreusch J, Stolz W, Argenziano G, et al. When all you have is a dermatoscope — start looking at the nails. Dermatol Pract Concept. 2014;4(4):11–20. doi: 10.5826/dpc.0404a02Dowlati E, Dovico J, Unwin B. Skin hyperpigmentation and melanonychia from chronic doxycycline use. Ann Pharmacother. 2015;49(10):1175–1176. doi: 10.1177/1060028015598166Damevska K, Gocev G, Pollozahani N, Nikolovska S, Neloska L. Onychomadesis following cutaneous vasculitis. Acta Dermatovenerol Croat. 2017;25(1):77–79.Haber R, Khoury R, Kechichian E, Tomb R. Splinter hemorrhages of the nails: a systematic review of clinical features and associated conditions. Int J Dermatol. 2016;55(12):1304–1310. doi: 10.1111/ijd.13347Magid M, Mennella C, Kuhn H, Stamu-O’Brien C, Kroumpouzos G. Onychophagia and onychotillomania can be effectively managed. J Am Acad Dermatol. 2017;77(5):e143–e144. doi: 10.1016/j.jaad.2017.06.154Ghanizadeh A, Derakhshan N, Berk M. N-acetylcysteine versus placebo for treating nail biting, a double-blind randomized placebo controlled clinical trial. Antiinflamm Antiallergy Agents Med Chem. 2013;14(3):223–228. doi: 10.2174/1871523011312030003Berk M, Jeavons S, Dean OM, et al. Nail-biting stuff? The effect of N-acetyl cysteine on nail-biting. CNS Spear. 2009;14(7):357–360. doi: 10.1017/s1092852900023002