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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Vestnik dermatologii i venerologii</journal-id><journal-title-group><journal-title xml:lang="en">Vestnik dermatologii i venerologii</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник дерматологии и венерологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0042-4609</issn><issn publication-format="electronic">2313-6294</issn><publisher><publisher-name xml:lang="en">Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">16825</article-id><article-id pub-id-type="doi">10.25208/vdv16825</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The importance of basic skin care in the management of patients with acne</article-title><trans-title-group xml:lang="ru"><trans-title>Значение базового ухода за кожей в ведении пациентов с акне</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7765-7487</contrib-id><contrib-id contrib-id-type="spin">7601-0687</contrib-id><name-alternatives><name xml:lang="en"><surname>Kholodilova</surname><given-names>Natalya A.</given-names></name><name xml:lang="ru"><surname>Холодилова</surname><given-names>Наталья Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><email>kholodilova83@list.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8211-1665</contrib-id><contrib-id contrib-id-type="spin">1837-2098</contrib-id><name-alternatives><name xml:lang="en"><surname>Monakhov</surname><given-names>Konstantin N.</given-names></name><name xml:lang="ru"><surname>Монахов</surname><given-names>Константин Николаевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>knmonakhov@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Saint Petersburg First Pavlov State Medical University</institution></aff><aff><institution xml:lang="ru">Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-06-10" publication-format="electronic"><day>10</day><month>06</month><year>2025</year></pub-date><volume>101</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>39</fpage><lpage>47</lpage><history><date date-type="received" iso-8601-date="2024-09-05"><day>05</day><month>09</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2025-04-03"><day>03</day><month>04</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Kholodilova N.A., Monakhov K.N.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Холодилова Н.А., Монахов К.Н.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Kholodilova N.A., Monakhov K.N.</copyright-holder><copyright-holder xml:lang="ru">Холодилова Н.А., Монахов К.Н.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikdv.ru/jour/article/view/16825">https://vestnikdv.ru/jour/article/view/16825</self-uri><abstract xml:lang="en"><p>Acne is a chronic widespread skin disease that significantly reduces the quality of life of patients, in which timely, effective and safe treatment is necessary. Due to the steady increase in the number of patients with this dermatosis, the lesion of open skin areas with this disease, the progression of the disease, the development of its severe forms, most patients develop psycho-emotional disorders up to severe depression and social and professional maladaptation occurs. This requires a clear understanding of the pathogenesis of dermatosis and the appointment of pathogenetically based therapy to patients. The review presents a modern view of the pathogenesis and methods of treatment of the disease, justifies the use of basic skin care products using dermatocosmetics to increase the effectiveness of disease therapy and achieve a lasting clinical effect. The article proves the important role of restoring the skin microbiome in acne patients, tells about the positive effect of bacterial lysates and metabiotics on the skin. Based on the data of clinical studies, the expediency of adding bacterial lysates to dermatocosmetics has been proven to restore the skin barrier, reduce inflammation and better tolerability of external and systemic drugs for the treatment of acne. The possibilities of skin care for patients with acne with the help of a line of products called Cinovit are presented.</p></abstract><trans-abstract xml:lang="ru"><p>Акне — хроническое распространенное заболевание кожи, значительно снижающее качество жизни пациентов, при котором необходимо своевременное, эффективное и безопасное лечение. В связи с неуклонным ростом числа больных данным дерматозом, поражением при этой болезни открытых участков кожи, прогрессированием заболевания, развитием его тяжелых форм у большинства пациентов появляются психоэмоциональные расстройства вплоть до тяжелой депрессии и возникает социальная и профессиональная дезадаптация. Это требует четкого понимания патогенеза дерматоза и назначения пациентам патогенетически обоснованной терапии. В обзоре изложен современный взгляд на патогенез и методы лечения заболевания, обосновано применение средств базового ухода за кожей с использованием дерматокосметики для повышения эффективности терапии заболевания и достижения стойкого клинического эффекта. Показана важная роль восстановления микробиома кожи у больных акне, рассказано о положительном действии на кожу лизатов бактерий и метабиотиков. Основываясь на данных клинических исследований, доказана целесообразность добавления в дерматокосметику лизатов бактерий для восстановления кожного барьера, уменьшения воспаления и лучшей переносимости наружных и системных препаратов для лечения акне. Представлены возможности ухода за кожей пациентов с акне с помощью линейки средств Циновит.</p></trans-abstract><kwd-group xml:lang="en"><kwd>acne</kwd><kwd>dermatocosmetics</kwd><kwd>basic skin care</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>акне</kwd><kwd>дерматокосметика</kwd><kwd>базовый уход за кожей</kwd></kwd-group><funding-group><funding-statement xml:lang="en">The manuscript was prepared with the financial support of the pharmaceutical company Pharmtec</funding-statement><funding-statement xml:lang="ru">Рукопись подготовлена при финансовой поддержке фармацевтической компании ООО «Фармтек»</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Федеральные клинические рекомендации по ведению больных акне. М.; 2020. 33 с. [Federal clinical guidelines for the management of acne patients. Мoscow; 2020. 33 p. 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