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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Vestnik dermatologii i venerologii</journal-id><journal-title-group><journal-title xml:lang="en">Vestnik dermatologii i venerologii</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник дерматологии и венерологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0042-4609</issn><issn publication-format="electronic">2313-6294</issn><publisher><publisher-name xml:lang="en">Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">16865</article-id><article-id pub-id-type="doi">10.25208/vdv16865</article-id><article-id pub-id-type="edn">mckiiy</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>GUIDELINES FOR PRACTITIONERS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Successful experience of secukinumab therapy in a patient with severe chronic suppurative hidradenitis</article-title><trans-title-group xml:lang="ru"><trans-title>Успешный опыт терапии секукинумабом пациента с тяжелой формой хронического гнойного гидраденита</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5524-0237</contrib-id><contrib-id contrib-id-type="spin">6289-2960</contrib-id><name-alternatives><name xml:lang="en"><surname>Bakhlykova</surname><given-names>Elena A.</given-names></name><name xml:lang="ru"><surname>Бахлыкова</surname><given-names>Елена Анатольевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), Assistant Professor</p></bio><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><email>elbah@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8670-7223</contrib-id><contrib-id contrib-id-type="spin">4377-8101</contrib-id><name-alternatives><name xml:lang="en"><surname>Khobeysh</surname><given-names>Marianna M.</given-names></name><name xml:lang="ru"><surname>Хобейш</surname><given-names>Марианна Михайловна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), Assistant Professor</p></bio><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><email>mkhobeysh@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-8733-9028</contrib-id><name-alternatives><name xml:lang="en"><surname>Sadovnichaia</surname><given-names>Marya S.</given-names></name><name xml:lang="ru"><surname>Садовничая</surname><given-names>Мария Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dermatovenerologist</p></bio><bio xml:lang="ru"><p>врач-дерматовенеролог</p></bio><email>stargardveid@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Tyumen State Medical University</institution></aff><aff><institution xml:lang="ru">Тюменский государственный медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">First Saint Petersburg State Medical University named after Academician I.P. Pavlov</institution></aff><aff><institution xml:lang="ru">Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Regional Dermatovenerologic Clinic</institution></aff><aff><institution xml:lang="ru">Областной кожно-венерологический диспансер</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-07-09" publication-format="electronic"><day>09</day><month>07</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-08-04" publication-format="electronic"><day>04</day><month>08</month><year>2025</year></pub-date><volume>101</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>68</fpage><lpage>74</lpage><history><date date-type="received" iso-8601-date="2025-02-07"><day>07</day><month>02</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-06-25"><day>25</day><month>06</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Bakhlykova E.A., Khobeysh M.M., Sadovnichaia M.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Бахлыкова Е.А., Хобейш М.М., Садовничая М.С.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Bakhlykova E.A., Khobeysh M.M., Sadovnichaia M.S.</copyright-holder><copyright-holder xml:lang="ru">Бахлыкова Е.А., Хобейш М.М., Садовничая М.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikdv.ru/jour/article/view/16865">https://vestnikdv.ru/jour/article/view/16865</self-uri><abstract xml:lang="en"><p>Severe forms of suppurative hidradenitis are characterized by a chronic recurrent course, accompanied by active inflammation, formation of nodes and abscesses, fistulous tracts with abundant purulent discharge and scarring. The case narrative concerns a patient who was not diagnosed with chronic suppurative hidradenitis for a long time. Misdiagnoses included “acne inversa”, “chronic furunculosis”, “chronic pyoderma”, and “secondary immunodeficiency”. The patient received short courses of antibacterial drugs, isotretinoin, systemic glucocorticosteroids, and ineffective surgical treatment. The lack of a correct diagnosis, inappropriate management strategy, and ineffective therapy over several years resulted in disease progression and patient’s disability and incapacity. The diagnosis of chronic purulent hidradenitis and administration of secukinumab yielded positive outcomes. Twelve months of secukinumab treatment resulted in sustained remission. The case narrative concerning the patient with severe suppurative hidradenitis showed that the treatment can be effective and that the drug is tolerated well.</p></abstract><trans-abstract xml:lang="ru"><p>Тяжелые формы гнойного гидраденита характеризуются хроническим рецидивирующим течением, сопровождаются активным воспалением, формированием узлов и абсцессов, свищевых ходов с обильным гнойным отделяемым, рубцовыми изменениями. Описан клинический случай пациента, которому длительно не диагностировали хронический гнойный гидраденит. Ошибочно ставились такие диагнозы, как «инверсные акне», «хронический фурункулез», «хроническая пиодермия», «вторичный иммунодефицит». Пациент получал терапию короткими курсами антибактериальных препаратов, изотретиноином, системными глюкокортикостероидами, хирургическое лечение без эффекта. Отсутствие правильного диагноза, неверная тактика ведения, неэффективность проводимой на протяжении нескольких лет терапии привели к распространению процесса, нарушению трудоспособности и инвалидизации пациента. Постановка диагноза «хронический гнойный гидраденит» и назначение секукинумаба позволили получить положительный результат. Лечение секукинумабом в течение 12 месяцев обеспечило стойкую ремиссию. Клинический случай применения секукинумаба у пациента с тяжелой формой гнойного гидраденита показал, что лечение может быть эффективным и этот препарат хорошо переносится.</p></trans-abstract><kwd-group xml:lang="en"><kwd>hydradenitis suppurativa</kwd><kwd>secukinumab</kwd><kwd>case report</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>гнойный гидраденит</kwd><kwd>секукинумаб</kwd><kwd>клинический случай</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Хайрутдинов В.Р., Бурова С.А., Олисова О.Ю., Соколовский Е.В., Кохан М.М., Котрехова Л.П., и др. Гнойный гидраденит: обзор международных клинических рекомендаций по диагностике и лечению заболевания. Вестник дерматологии и венерологии. 2024;100(3):7–16. [Khairutdinov VR, Burova SA, Olisova OYu, Sokolovskiy EV, Kohan MM, Kotrekhova LP, et al. 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