Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov17610.25208/0042-4609-2015-91-5-42-52ArticlesСтатьиШирокое многообразие кератинов человекаYunusbaevaM. M.ЮнусбаеваМ. М.
Russian Federation
milyausha_ufa@mail.ruYunusbaevB. B.ЮнусбаевБ. Б.
Russian Federation
ValievR. R.ВалиевР. Р.
Russian Federation
KhammatovaA. A.ХамматоваА. А.
Russian Federation
KhusnutdinovaE. K.ХуснутдиноваЭ. К.
Russian Federation
Institute of Biochemistry and Genetics of Ufa Scientific CenterФГБУН Институт биохимии и генетикиBashkir State UniversityФГБОУ ВПО «Башкирский государственный университет»Bashkir Dermatovenerology dispensaryГАУЗ Республиканский кожно-венерологический диспансер № 124102015915425224082017Copyright ©; 2015, Yunusbaeva M.M., Yunusbaev B.B., Valiev R.R., Khammatova A.A., Khusnutdinova E.K.Copyright ©; 2015, Юнусбаева М.М., Юнусбаев Б.Б., Валиев Р.Р., Хамматова А.А., Хуснутдинова Э.К.2015Yunusbaeva M.M., Yunusbaev B.B., Valiev R.R., Khammatova A.A., Khusnutdinova E.K.Юнусбаева М.М., Юнусбаев Б.Б., Валиев Р.Р., Хамматова А.А., Хуснутдинова Э.К.https://creativecommons.org/licenses/by/4.0https://vestnikdv.ru/jour/article/view/176

А review presents systematic data about the diversity of human keratins. The results of numerous studies concerning the structure and functions of keratins, their distribution in various cells and tissues were summarized. The role of these proteins in the development of human hereditary diseases, as well as modern approaches in use keratins in immunohistochemistry and perspectives of their further studies are discussed.

Представлены систематизированные данные о разнообразии кератинов человека. Обобщены результаты многочисленных исследований в области изучения структуры и функций кератинов, их распределения в различных клетках и тканях организма. Обсуждаются роль данных белков в развитии наследственных заболеваний человека, а также современные подходы к использованию кератинов в иммуногистохимии и перспективы их дальнейших исследований.

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