Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov25910.25208/0042-4609-2016-92-4-54-58CLINICAL CASE REPORTSНАБЛЮДЕНИЕ ИЗ ПРАКТИКИAnti-cytokine therapy of a patient suffering from psoriatic arthritisАнтицитокиновая терапия пациента с псориатическим артритомOnipchenkoV. V.ОнипченкоВ. В.
Russian Federation
SergeevaI. G.СергееваИТ. .
Russian Federation
KrinitsyinaYu. M.КриницынаЮ. М.
Russian Federation
KondrashovaA. A.КондрашоваА. А.
Russian Federation
An.al.kondrashova@yandex.ruPahomovaV. V.ПахомоваВ. В.
Russian Federation
HismatulinaN. V.ХисматулинаН. В.
Russian Federation
ГБУЗ НСО «Новосибирский областной кожно-венерологический диспансер»ФГАОУ ВО «Новосибирский национальный исследовательский государственный университет»ФГБ НУ «Институт молекулярной патологии и патоморфологии»24082016924545824082017Copyright ©; 2016, Onipchenko V.V., Sergeeva I.G., Krinitsyina Y.M., Kondrashova A.A., Pahomova V.V., Hismatulina N.V.Copyright ©; 2016, Онипченко В.В., Сергеева И..., Криницына Ю.М., Кондрашова А.А., Пахомова В.В., Хисматулина Н.В.2016Onipchenko V.V., Sergeeva I.G., Krinitsyina Y.M., Kondrashova A.A., Pahomova V.V., Hismatulina N.V.Онипченко В.В., Сергеева И..., Криницына Ю.М., Кондрашова А.А., Пахомова В.В., Хисматулина Н.В.https://creativecommons.org/licenses/by/4.0https://vestnikdv.ru/jour/article/view/259

The article presents a clinical case study of an efficient therapy with infliximab used for a 33-year-old patient with a severe course of psoriasis, psoriatic arthritis, psoriatic onychopathy; chronic hepatitis C with the minimum activity, replication phase; hyper- and normatrophic scars affecting 40% of the body surface; cicatricial contractures; complicated posterior polar cataract of both eyes; secondary amyloidosis of the kidneys with a nephrotic syndrome. It also demonstrates the significance of the anti-cytokine therapy as a method of choice in a complicated clinical situation.

Представлено клиническое наблюдение эффективной терапии инфликсимабом пациента 33 лет с тяжелым течением псориаза, псориатическим артритом, псориатической ониходистрофией; хроническим гепатитом С (минимальной степени активности, репликативная фаза) фиброзом печени I степени; гипер- и нормотрофическими рубцами 40% поверхности тела, рубцовыми контрактурами; осложненной заднеполярной катарактой обоих глаз; вторичным амилоидозом почек с нефротическим синдромом. Показано назначение антицитокиновой терапии как метода выбора в сложной клинической ситуации.

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