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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Vestnik dermatologii i venerologii</journal-id><journal-title-group><journal-title xml:lang="en">Vestnik dermatologii i venerologii</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник дерматологии и венерологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0042-4609</issn><issn publication-format="electronic">2313-6294</issn><publisher><publisher-name xml:lang="en">Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">266</article-id><article-id pub-id-type="doi">10.25208/0042-4609-2016-92-5-25-31</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>НАУЧНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Assessment of vegetative, neurohumoral and psycho-emotional disorders in patients with atopic dermatitis of varying severity</article-title><trans-title-group xml:lang="ru"><trans-title>Оценка вегетативных, нейрогуморальных и психоэмоциональных нарушений у больных атопическим дерматитом различной степени тяжести</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Patrushev</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Патрушев</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>alexpat2@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gutka</surname><given-names>V. O.</given-names></name><name xml:lang="ru"><surname>Гутка</surname><given-names>В. О.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sukharev</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Сухарев</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Samtsov</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Самцов</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zavalskaya</surname><given-names>E. I.</given-names></name><name xml:lang="ru"><surname>Завальская</surname><given-names>Е. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Military Medical Academy named after S.M. Kirov Ministry of Defense of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБВОУ ВПО «Военно-медицинская академия им. С.М. Кирова» МО РФ</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">PB GBUZ “HPC №10 - Dermatology and Venereology Clinic”</institution></aff><aff><institution xml:lang="ru">СПб ГБУЗ «КВД № 10 - клиника дерматологии и венерологии»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-10-24" publication-format="electronic"><day>24</day><month>10</month><year>2016</year></pub-date><volume>92</volume><issue>5</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>25</fpage><lpage>31</lpage><history><date date-type="received" iso-8601-date="2017-08-24"><day>24</day><month>08</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Patrushev A.V., Gutka V.O., Sukharev A.V., Samtsov A.V., Zavalskaya E.I.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, Патрушев А.В., Гутка В.О., Сухарев А.В., Самцов А.В., Завальская Е.И.</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Patrushev A.V., Gutka V.O., Sukharev A.V., Samtsov A.V., Zavalskaya E.I.</copyright-holder><copyright-holder xml:lang="ru">Патрушев А.В., Гутка В.О., Сухарев А.В., Самцов А.В., Завальская Е.И.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikdv.ru/jour/article/view/266">https://vestnikdv.ru/jour/article/view/266</self-uri><abstract xml:lang="en"><p>Goal of the study. evaluation of psycho-vegetative disorders in patients with atopic dermatitis, and the determination of their influence on the severity of the disease. Material and methods. The study involved 72 patients with atopic dermatitis aged 18 to 46 years (men - 41, women - 31). The control group, similar in age and sex characteristics, and 30 healthy volunteers. All patients underwent an individual computer study psychophysiological and emotional state of a human body with a digital telemetry hardware and software system - analyzer of biorhythms «Omega-M» Scientific-production company «Dynamics» (Saint-Petersburg). Evaluates the performance of the autonomic, neurohumoral and central regulation, as well as the integral indicators of the functional state of the organism. Quality of life assessed by questionnaire DLQI (dermatology life quality index), the severity of the disease was determined by the index SCORAD (scoring atopic dermatitis). Results. Autonomic disorders were diagnosed in 75.0% of patients (54/72), represented mainly sympathicotonia and centralization of heart rhythm. Neurodynamic methods and fractal analysis of cardiac rhythm disorders of neurohumoral regulation and psycho-emotional diagnosed respectively in 69.4% (50/72) and 76.6% (53/72) of patients with atopic dermatitis. A moderate correlation between the severity of the disease and some indicators (IV, IVE, VR, C1, D1) showing violations of the vegetative and central regulation (0,25 &lt; Ir<sub>s</sub>I &lt; 0,75).</p></abstract><trans-abstract xml:lang="ru"><p>Цель исследования: оценить психовегетативные нарушения у больных атопическим дерматитом и определить их влияние на тяжесть течения заболевания. Материал и методы. Обследованы 72 больных атопическим дерматитом: 41 мужчина, 31 женщина в возрасте от 18 до 46 лет. Группу контроля, сходную по возрастным и половым характеристикам, составили 30 здоровых добровольцев. Проводилось индивидуальное компьютерное исследование психофизиологического и эмоционального состояния организма человека с помощью цифрового телеметрического аппаратно-программного комплекса - анализатора биоритмов «Омега-М» научно-производственной фирмы «Динамика» (Санкт-Петербург). Оценивались показатели вегетативной, нейрогуморальной и центральной регуляции с применением метода нейродинамического анализа. Качество жизни пациентов определялось по результатам опросника ДИКЖ (дерматологический индекс качества жизни), тяжесть течения заболевания - по индексу SCORAD (scoring atopic dermatitis). Результаты. По данным вариационной пульсометрии вегетативные нарушения диагностированы у 75,0% (54/72) больных, представлены преимущественно симпатикотонией и централизацией управления сердечным ритмом. Методами нейродинамического и фрактального анализов сердечного ритма нарушения нейрогуморальной и психоэмоциональной регуляции диагностированы соответственно у 69,4% (50/72) и 76,6% (53/72) больных атопическим дерматитом. Выявлена умеренная корреляционная связь между тяжестью течения заболевания и некоторыми показателями (ИН, ИВР, ВР, С1, D1), характеризующими нарушения вегетативной и центральной регуляции (0,25 &lt; Ir<sub>s</sub>I &lt; 0,75).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>атопический дерматит</kwd><kwd>нейродинамический анализ</kwd><kwd>вегетативные нарушения</kwd><kwd>психоэмоциональные нарушения</kwd><kwd>atopic dermatitis</kwd><kwd>neurodynamic analysis</kwd><kwd>autonomic disorders</kwd><kwd>psycho-emotional disorders</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Mohajeri S., Newman S.A. Review of evidence for dietary influences on atopic dermatitis. 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