Vestnik dermatologii i venerologiiVestnik dermatologii i venerologii0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov26810.25208/0042-4609-2016-92-5-39-43Facial skin follllicular hyperkeratosis of patients with basal cell carcinomaZhuchkovM. V.misha.juchkov@gmail.comBychkovaYu. S.noemail@neicon.ruTarasovaM. A.noemail@neicon.ruRyazan Regional Clinical Skin and Venereal Diseases Dispensary24102016925394324082017Copyright © 2016, Zhuchkov M.V., Bychkova Y.S., Tarasova M.A.2016This article provides a clinical observation of paraneoplastic syndrome of a patient with basal cell carcinoma of skin. Authors present clinical features of the described for the first time, paraneoplastic retentional follicular hyperkeratosis of facial area.базалиомапаранеопластический синдромдерматоскопияфолликулярный гиперкератозbasal cell carcinomaparaneoplastic syndromedermatoscopyfollicular hyperkeratosis[Li C., Athar M. Ionizing Radiation Exposure and Basal Cell Carcinoma Pathogenesis. Radiation Research 2016; 185 (3): 217-228.][Wu S. et al. History of Severe Sunburn and Risk 5. of Skin Cancer Among Women and Men in 2 Prospective Cohort Studies. American Journal of Epidemiology 2016; 183 (9): 824-833. 6.][Bower C.P. et al. Basal cell carcinoma and risk of subsequent malignancies: A cancer registry-based study in southwest England. Journal of the American Academy of Dermatology 2000; 42 (6): 988-991. 7.][Masud D., Moustaki M., Staruch R., Dheansa B. incomplete excision and results of re-excision. Journal of Plastic, Reconstructive & Aesthetic Surgery. 2016; 69 (5): 652-656.][Khalesi M. et al. Basal cell carcinomas on sun-protected vs. sun-exposed body sites: a comparison of phenotypic and environmental risk factors. Photodermatol Photoimmunol Photomed 2015; 31 (4): 202-211][Maly T.J., Sligh J.E. Defining locally advanced Basal cell carcinoma. Journal Drugs Derm 2014; 13 (5): 528-529][Lukitsch O., Gebhardt K.P., Kövary P.M. Follicular hyperkeratosis and cryocrystalglobulinemia syndrome. Occurrence in a patient with multiple myeloma. Arch Derm 1985; 121 (6): 795-798.][Bork K., Böckers M., Pfeifle J. Pathogenesis of paraneoplastic follicular hyperkeratotic spicules in multiple myeloma. Follicular and epidermal accumulation of IgG dysprotein and cryoglobulin. Arch Derm 1990;126 (4): 509-513.][Weenig R.H., Mehrany K. Dermal and pannicular manifestations of internal malignancy. Derm Clin 2008; 26 (1): 31-43.][Clark C.M., Furniss M., Mackay-Wiggan J.M. Basal cell carcinoma: an evidence-based treatment update. Am J Clin Derm 2014; 15 (3): 197-216]