Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov27410.25208/0042-4609-2016-92-5-79-83DRUG TREATMENT IN DERMATOVENEROLOGYФАРМАКОТЕРАПИЯ В ДЕРМАТОВЕНЕРОЛОГИИFeasibility of combination the outer antibakterialnoy therapy and preparation azelaic acid for treatment of acneЦелесообразность комбинации наружной антибактериальной терапии и препарата азелаиновой кислоты в лечении больных акнеDombrovskayaD. K.ДомбровскаяД. К.
Russian Federation
zakomarik@gmail.comMonakhovK. N.МонаховК. Н.
Russian Federation
zakomarik@gmail.comPavlov First Saint Petersburg State Medical UniversityГБОУ ВПО «Первый Санкт-Петербургский государственный медицинский университет им. академика И.П. Павлова» Минздрава России24102016925798324082017Copyright ©; 2016, Dombrovskaya D.K., Monakhov K.N.Copyright ©; 2016, Домбровская Д.К., Монахов К.Н.2016Dombrovskaya D.K., Monakhov K.N.Домбровская Д.К., Монахов К.Н.https://creativecommons.org/licenses/by/4.0https://vestnikdv.ru/jour/article/view/274

The review presents modern views on the pathogenesis of acne. The data of foreign and domestic clinical trials to study the efficacy and safety of drugs containing 1% clindamycin and 15% azelaic acid used to treat acne. The mechanisms of the effects of these drugs on the main elements of the pathogenesis of acne. Substantiates the appropriateness of the drug combination of clindamycin and azelaic acid in the treatment of acne patients.

Освещены современные представления о патогенезе акне. Изложены данные зарубежных и отечественных клинических исследований по изучению эффективности и безопасности препаратов, содержащих 1% клиндамицин и 15% азелаиновую кислоту, применяемых для лечения акне. Рассмотрены механизмы воздействия этих препаратов на основные звенья патогенеза акне. Обоснована целесобразность комбинации препаратов клиндамицина и азелаиновой кислоты в лечении больных акне.

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