Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov28110.25208/0042-4609-2016-92-6-20-26SHORT COMMUNICATIONКРАТКИЕ СООБЩЕНИЯObesity related skin disordersЗаболевания кожи, ассоциированные с ожирениемGorlanovI. A.ГорлановИ. А.
Russian Federation
venerology@gmail.comZaslavskiyD. V.ЗаславскийД. В.
Russian Federation
venerology@gmail.comLeinaL. M.ЛеинаЛ. М.
Russian Federation
venerology@gmail.comMilyavskayaI. R.МилявскаяИ. Р.
Russian Federation
venerology@gmail.comSt. Petersburg State Pediatric Medical UniversityФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Минздрава России24122016926202624082017Copyright ©; 2016, Gorlanov I.A., Zaslavskiy D.V., Leina L.M., Milyavskaya I.R.Copyright ©; 2016, Горланов И.А., Заславский Д.В., Леина Л.М., Милявская И.Р.2016Gorlanov I.A., Zaslavskiy D.V., Leina L.M., Milyavskaya I.R.Горланов И.А., Заславский Д.В., Леина Л.М., Милявская И.Р.https://creativecommons.org/licenses/by/4.0https://vestnikdv.ru/jour/article/view/281

Obesity is a serious global problem. In recent years, it has been an increase in patients with obesity. In a review of literature presents data on the effect of obesity on the skin. It is responsible for the development of a number of dermatological diseases, including acantosis nigricans, akrohordony, follicular hyperkeratosis, infectious diseases of the skin. Against the background of obesity worsens psoriasis. The connection between obesity and atopic dermatitis.

Ожирение является серьезной медицинской проблемой во всем мире. В последние годы отмечается рост числа больных с ожирением. В обзоре литературы представлены данные о влиянии ожирения на кожу. Оно связано с развитием ряда дерматологических заболеваний, в том числе acantosis nigricans, акрохордонов, фолликулярного гиперкератоза, инфекционных заболеваний кожи. На фоне ожирения ухудшается течение псориаза. Обсуждается связь ожирения и атопического дерматита.

ожирениеacantosis nigricansакрохордоныфолликулярный гиперкератозпсориазатопический дерматитobesityacantosis nigricansacrochordonskeratosis pilarispsoriasisatopic dermatitisShipman A.R., Millington G.W.M. Obesity and the skin. Br J Dermatol 2011: 165 (4): 743-750.Tobin A., Ahern T., Rogers S. et al. The dermatological consequences of obesity. Int J dermatol 2013; 52; 927-932.Lau K., Hoger P.H. Skin diseases associated with obesity in children. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 2013; 56 (4): 539-42.Scheinfeld N.S. Obesity and dermatology. Clin. Dermatol. 2004; 22: 303-9.Yosipovitch G., DeVore A., Dawn A. Obesity and skin: skin physiology and skin manifestations of obesity. J Am Acad Dermatol 2007; 56 (6): 901-916.Millington G.W.M. Obesity, genetics and the skin. Clin Exp Dermatol 2013; 38 (1): 50-56.Loftier H., Aramaki J.U., Effendy I. The influence of body mass index on skin susceptibility to sodium lauryl sulphate. Skin Res Technol 2002; 8: 19-22.Guida B., Nino M., Perrino N.R. et al. The impact of obesity on skin disease and epidermal permeability barrier status. J Eur Acad Dermatol Venerol 2010; 24: 191-195.Nino M., Franzese A., Ruggiero Perrino N., Balato N. The effect of obesity on skin disease and epidermal permeability barrier status in children. Pediatr Dermatol 2012; 29 (5): 567-570.Garcia-Hidalgo L., Orozco-Torete R., Gonzalez-Barranco J. et al. Dermatoses in 156 obese adults. Obes Res 1999; 7: 299-302.Al-Mutairi N. Associated cutaneous diseases in obese adult patients: a prospective study from a skin referral care center. Med Princ Pract 2011; 20 (3): 248-52.Boza J.C., Trindade E.N., Peruzzo J., Rech L., Cestari T.F. Skin manifectations of obesity: a comparative study. J Eur Acad Dermatol Venereol 2012; 26: 1220-1223.Hercogova J., Ricceri F., Tripo L., Lotti T., Prignano F. Psoriasis and body mass index. Dermatol Ther 2010; 23: 152-154.Wolk K., Mallbris L., Larsson P., Rosenblad A., Vingard E., Stahle M. Excessive body weight and smoking associates with a high risk of onset of plaque psoriasis. Acta Derm Venereol 2009; 89: 492-497.Birtane M., Tuna H. The evaluation of plantar pressure distribution in obese and non-obese adults. Clin Biomech 2004; 19: 1055-9.Mann R.A., Mann J.A. Keratotic disorders of the plantar skin. Instr Course Lect 2004; 53: 287-302.Garcia-Hidalgo L. Dermatological complications of obesity. Am J Clin Dermatol 2002; 3: 497-506.Hud J.A. Jr, Cohen J.B., Wagner J.M., Cruz P.D. Jr. Prevalence and significance of acantosis nigricans in an adult obese population. Arch Dermatol 1992; 128: 941-4.Torley D., Bellus G.A., Munro C.S. Genes growth factors and acantosis nigricans. Br J Dermatol 2002; 147; 1096.Дерматология Фицпатрика в клинической практике. Вольф К., Голдсмит Л.А., Кац С.И., Джилкрест Б.А. и др. Пер. с англ. М; 2013.Rogalski C., Haustein U.F., Glander H.J., Paasch U. Extensive striae distensae as a result of topical corticosteroid therapy in psoriasis vulgaris. Acta Derm Venereol 2003; 83: 54-5.Hsu H.S., Chen W., Chen S.C., Ko F.D. Colored striae in obese children and adolescents. Zhong-hua Min Guo. Xiao Er Ke Yi Xue Hui Za Zhi 1996; 37: 349-52.Angeli A., Boccuzzi G., Frajria R., Bisbocci D. Adrenal gland function test in the differential diagnosis of sthenic obesity with pink striae. Folia Endocrinol. 1970; 23: 566-78.Kang S. Topical tretinoin therapy for management of early striae. J Am Acad Dermatol 1998; 39 (Suppl): S90-2.Yosipovitch G., Mevorah B., Mashiach J., Chan Y.H., David M. High body mass index, dry scaly leg skin and atopic conditions are highly associated with keratosis pilaris. Dermatology 2000; 201; 34-6.Gupta A.K., Ryder J.E., Lynch L.E., Tavakkol A. The use of terbinafine in the treatment of onychomycosis in adults and special populations: a review of the evidence. J Drugs Dermatol 2005; 4: 302-8.Herron M.D., Hinckley M., Hoffman M.S., Papenfuss J., Hansen C.B., Callis K.P. et al. Impact of obesity and smoking on psoriasis presentation and management. Arch Dermatol 2005; 14: 1527-34.Bremer S., Van Voorhess A.S., Hsu S., Korman N.J. at all. Obesity and psoriasis: from the Medical Board of the National Psoriasis Foundation. J Am Acad Dermatol 2010; 63 (6): 1058-69.Lindegard B. Diseases associated with psoriasis in a general population of 159,200 middle-aged, urban, native Swedes. Dermatologica 1986; 172: 298-304.Sakai R., Matsui S., Fukushima M., Yasuda H., Miyauchi H., Miyachi Y. Prognostic factor analysis for plaque psoriasis. Dermatology 2005; 211: 103-6.Setty A.R., Curhan G., Choi H.K. Obesity, waist circumference, weight change and the risk of psoriasis in women: Nurses Health Study II. Arch Intern Med 2007; 167: 1670-5.Kumar S., Han J., Li T., Qureshi A.A. Obesity, waist circumference, weight change and the risk of psoriasis in US women. J Eur Acad Dermatology Venereol 2013; 27 (10): 1293-1298.Paller A.S., Mercy K., Kwasny M.J., Choon S.E. and all. Association of pediatric psoriasis severity with excess and central adiposity: an international cross-sectional stu dy. JAMA Dermatol 2013; 149 (2): 166-76.Soltani-Arabshahi R, Wong B, Feny BJ et al. Obesity in early adulthood as a risk factor for psoriatic arthritis. Arch Dermatol 2010; 146: 721-6.Mahe E., MacCari F., Beauchet A. et al. Childhood-onset psoriasis: Association with future cardiovascular and metabolic comorbidities. Br J Dermatol 2013; 169 (4): 889-895.Shapiro J., Cohen D., David M. et al. The association between psoriasis, diabetes mellitus, and atherosclerosis in Israel: a case-control study. J Am Acad Dermatol 2007; 56: 629-34.Cohen A., Gilutz H., Henkin Y. et al. Psoriasis and the Metabolic Syndrome. Acta Derm Venereol 2007; 87 (6): 506-509.Koebnick C., Black M.N., Smith N., Der-Sarkissian J.K. et al. The association of psoriasis and elevated blood lipids in overweight and obese children. J Pediatr 2011; 159 (4): 577-83.Perez-Perez I., Allegue F., Caeiro J.I. et al. Severe psoriasis, morbid obesity and bariatric surgery. Clin Exp Dermatol 2009; 34: 421-2.Song A.Y., Rubin J.P., Thomas V. et al. Body image and quality of life in post massive weight loss body contouring patients. Obesity 2006; 14: 1626-36.Rucevic I., Perl A., Barisic-Drusko V., AdamPerl M. The role of the low energy diet in psoriasis vulgaris treatment. Coll Antropol 2003; 27 (Suppl. 1): 41-8.Higa-Sansone G., Szomstein S., Soto F., Brasecsco O., Cohen C., Rosenthal R.J. Psoriasis remission after laparoscopic Roux-en-Y gastric bypass for morbid obesity. Obes Surg 2004; 14: 1132-4.Jensen P., Zachariae C., Christensen R. et al. Effect of weight loss on the cardiovascular risk profile of obese patients with psoriasis. Acta Derm Venereol 2014; 94 (6): 691-694.Ковалева О.А., Амбросова Т.Н., Ащеулова Т.В. Адипокины: биологические, патофизиологические и метаболические эффекты. Внутренняя медицина 2009; 3: 15-23.Gerdes S., Rostami-Yazdi M., Mrowietz U. Adipokines and psoriasis. Exp Dermatol 2011; 20 (2): 81-87.Ceman A.A., Bozkurt S., Sav A. et al. Serum leptin levels, skin leptin and leptin receptor expression in psoriasis. Br J Dermatol 2008; 159: 820-6.Johnston A., Arnadottir S., Gudjonsson J.E. et al. Obesity in psoriasis: leptin and resistin as mediators of cutaneous inflammation. Br J Dermatol 2008; 159: 342-50.Coimbra S., Oliveira H., Reis F. et al. Circulating adipokine levels in Portugese patients with psoriasis vulgaris according to body mass index, severity and therapy. J Eur Acad Dermatol Venereol 2010; 24: 1386-94.Chen Y., Rennie D., Cormier Y., Dosman J. Association between obesity and atopy in adults. Int Arch Allergy Immunol 2010; 153 (4): 372-377.Silverberg J.I., Silverberg N.B., Lee-Wong M. Association between atopic dermatitis and obesity in adulthood. Br J Dermatol 2012; 166 (3): 498-504.Baruwa P., Sarmah K.R. Obesity and asthma. Lung India 2013; 30 (1): 38-46.Abdul Wahab A., Maarafiya M.M., Soliman A., Younes NBM, Chandra P. Serum Leptin and Adiponectin Levels in Obese and Nonobese Asthmatic School Children in relation to Asthma Control. J Allergy 2013; 2013: 654104.Agrawal A., Sood A., Linneberg A., Ghosh B. Mechanistic understanding of the effect of obesity on asthma and allergy. J Allergy 2013; 2013: 598904.Silverberg J.I., Kleiman E., Lev-Tov H. at all. Association between obesity and atopic dermatitis in childhood: A case-control study. J Allergy Clin Immunol 2011; 127 (5): 1180-1186.Silverberg J.I., Simpson E.L. Association between obesity and eczema prevalence, severity and poorer health in US adolescents. Dermat contact atopic Occup drug 2014; 25 (4): 172-81.Hakala K., Stenius-Aarniala B., Sovijarvi A. Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma. Chest 2000; 118: 1315-21.Murray C.S., Canoy D., Buchan I., Woodcock A. and all. Body mass index in young children and allergic disease: gender differences in a longitudinal study Clin Experimental Allergy 2010; 41: 78-85.Fantuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 2005; 115: 911-20.Nagel G., Koenig W., Rapp K., Wabitsch M., Zoellner I., Weiland S.K. Associations of adipokines with asthma, rhinoconjunctivitis, and eczema in German schoolchildren. Pediatr Allergy Immunol 2009; 20: 81-8.Guler N., Kirerlari E., Ones U., Tamay Z. and all. Leptin: does role in childhood astma? J allergy Clin Immunol 2004; 114 (2): 254-9.Горланов И.А., Заславский Д.В., Милявская И.Р., Леина Л.М., Оловянишников О.В., Куликова С.Ю. Детская дерматовенерология: Учебник. М: Академия 2012; 352