Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov29810.25208/0042-4609-2017-93-1-55-63CLINICAL CASE REPORTSНАБЛЮДЕНИЕ ИЗ ПРАКТИКИGeneralized eruptive histiocytoma: case reportГенерализованная эруптивная гистиоцитома: описание случаяChikinV. V.ЧикинВ. В.
Russian Federation
chikin@cnikvi.ruZnamenskajaL. F.ЗнаменскаяЛ. Ф.
Russian Federation
KaramovaA. JE.КарамоваА. Э.
Russian Federation
Smol'jannikovaV. A.СмольянниковаВ. А.
Russian Federation
NefedovaM. A.НефедоваМ. А.
Russian Federation
State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian FederationФГБУ «Государственный научный центр дерматовенерологии и косметологии» Минздрава РоссииI.M. Sechenov First Moscow State Medical UniversityГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России24022017931556324082017Copyright ©; 2017, Chikin V.V., Znamenskaja L.F., Karamova A.J., Smol'jannikova V.A., Nefedova M.A.Copyright ©; 2017, Чикин В.В., Знаменская Л.Ф., Карамова А.Э., Смольянникова В.А., Нефедова М.А.2017Chikin V.V., Znamenskaja L.F., Karamova A.J., Smol'jannikova V.A., Nefedova M.A.Чикин В.В., Знаменская Л.Ф., Карамова А.Э., Смольянникова В.А., Нефедова М.А.https://creativecommons.org/licenses/by/4.0https://vestnikdv.ru/jour/article/view/298

The case of generalized eruptive histiocytoma (GEH) in woman of 49 years old is reported. GEH is a rare disease relating to non-langerhans cell histiocytoses which are based on a benign reactive proliferation of histiocytes with immunophenotype inconsistent with Langerhans cells. As a result of treatment with methotrexate and betamethasone the improvement in skin condition was achieved.

Описан случай генерализованной эруптивной гистиоцитомы (ГЭГ) у женщины 49 лет. ГЭГ - редкое заболевание, относящееся к нелангергансоклеточным гистиоцитозам, в основе которых лежит реактивная доброкачественная пролиферация гистиоцитов с иммунофенотипом, не соответствующим клеткам Лангерганса. В результате проведенного лечения бетаметазоном и метотрексатом достигнуто улучшение состояния кожи.

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