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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Vestnik dermatologii i venerologii</journal-id><journal-title-group><journal-title xml:lang="en">Vestnik dermatologii i venerologii</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник дерматологии и венерологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0042-4609</issn><issn publication-format="electronic">2313-6294</issn><publisher><publisher-name xml:lang="en">Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">462</article-id><article-id pub-id-type="doi">10.25208/0042-4609-2019-95-1-15-20</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Sneddon — Wilkinson disease: Review of the modern literature</article-title><trans-title-group xml:lang="ru"><trans-title>Субкорнеальный пустулез Снеддона — Уилкинсона: Обзор современной литературы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7689-8350</contrib-id><name-alternatives><name xml:lang="en"><surname>Drozhdina</surname><given-names>M. B.</given-names></name><name xml:lang="ru"><surname>Дрождина</surname><given-names>М. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.), Associate Professor, Department of Dermatovenereology and Cosmetology</p></bio><bio xml:lang="ru"><p>к.м.н., доцент, доцент кафедры дерматовенерологии и косметологии</p></bio><email>drozhdina@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6220-8304</contrib-id><name-alternatives><name xml:lang="en"><surname>Koshkin</surname><given-names>S. V.</given-names></name><name xml:lang="ru"><surname>Кошкин</surname><given-names>С. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.), Prof., Departmental Head, Department of Dermatovenereology and Cosmetology</p></bio><bio xml:lang="ru"><p>д.м.н., доцент, профессор, заведующий кафедрой дерматовенерологии и косметологии</p></bio><email>koshkin_sergei@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kirov State Medical University, Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">Кировский государственный медицинский университет Министерства здравоохранения Российской Федерации</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-03-02" publication-format="electronic"><day>02</day><month>03</month><year>2019</year></pub-date><volume>95</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>15</fpage><lpage>20</lpage><history><date date-type="received" iso-8601-date="2019-05-30"><day>30</day><month>05</month><year>2019</year></date><date date-type="accepted" iso-8601-date="2019-05-30"><day>30</day><month>05</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, Drozhdina M.B., Koshkin S.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, Дрождина М.Б., Кошкин С.В.</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">Drozhdina M.B., Koshkin S.V.</copyright-holder><copyright-holder xml:lang="ru">Дрождина М.Б., Кошкин С.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikdv.ru/jour/article/view/462">https://vestnikdv.ru/jour/article/view/462</self-uri><abstract xml:lang="en"><p>The article provides a current overview of the correlation between a rare dermatosis — subcorneal pustulosis (Sneddon — Wilkinson disease) — and various diseases of internal organs; features of immunological changes; the role of desmocollin 1, chemoatractants, interleukin-1β, interleukin-6, interleukin-8, interleukin-10, leukotriene B4, tumour necrosis factor-alpha and K5a complement fraction in the pathogenesis of the disease. In this work, the authors describe the features of the clinical picture of the disease, as well as diagnostic criteria, including the use of serum protein electrophoresis. Histological features of the disease are discussed in detail. In addition, modern methods for treating this disease, including the use of dapsone, acitretin, infliximab, PUVA therapy are presented.</p></abstract><trans-abstract xml:lang="ru"><p>В статье описаны современные данные о взаимосвязи редкого дерматоза, субкорнеального пустулеза Снеддона — Уилкинсона, с различными заболеваниями внутренних органов, об особенностях иммунологических изменений, роли десмоколлина-1, хемоаттрактантов, интерлейкина-1β, интерлейкина-6, интерлейкина-8, интерлейкина-10, лейкотриена В4, фактора некроза опухоли-альфа и фракции К5а комплемента в патогенезе заболевания. Описаны особенности клинической картины заболевания, критерии диагностики, включая применение электрофореза сывороточного протеина. Подробно обсуждены гистологические особенности заболевания. Представлены современные методики лечения данного заболевания, включая применение дапсона, ацитретина, инфликсимаба, ПУВА-терапии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>subcorneal pustular dermatosis</kwd><kwd>IgA monoclonal gammopathy</kwd><kwd>desmocollin 1</kwd><kwd>chemoattractants</kwd><kwd>interleukin-1β</kwd><kwd>interleukin-6</kwd><kwd>interleukin-8</kwd><kwd>interleukin-10</kwd><kwd>leukotriene B4</kwd><kwd>tumor necrosis factor</kwd><kwd>serum protein electrophoresis</kwd><kwd>dapsone</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>субкорнеальный пустулез</kwd><kwd>IgA-моноклональная гаммапатия</kwd><kwd>десмоколлин-1</kwd><kwd>хемоаттрактанты</kwd><kwd>интерлейкин-1β</kwd><kwd>интерлейкин-6</kwd><kwd>интерлейкин-8</kwd><kwd>интерлейкин-10</kwd><kwd>лейкотриен В4</kwd><kwd>фактор некроза опухоли</kwd><kwd>электрофорез сывороточного протеина</kwd><kwd>дапсон</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. 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