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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Vestnik dermatologii i venerologii</journal-id><journal-title-group><journal-title xml:lang="en">Vestnik dermatologii i venerologii</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник дерматологии и венерологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0042-4609</issn><issn publication-format="electronic">2313-6294</issn><publisher><publisher-name xml:lang="en">Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">528</article-id><article-id pub-id-type="doi">10.25208/0042-4609-2019-95-6-14-21</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Precision therapy for psoriasis patients</article-title><trans-title-group xml:lang="ru"><trans-title>Прецизионная терапия больных псориазом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zhukov</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Жуков</surname><given-names>А. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.), Doctoral Candidate, Department of Skin and Sexually Transmitted Diseases</p><p>Akademika Lebedeva str., 6, Saint Petersburg, 194044, Russian Federation </p></bio><bio xml:lang="ru"><p>к.м.н., докторант кафедры кожных и венерических болезней  194044, Российская Федерация, г. Санкт-Петербург, ул. Академика Лебедева, д. 6</p></bio><email>doctor-vma@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khairutdinov</surname><given-names>V. R.</given-names></name><name xml:lang="ru"><surname>Хайрутдинов</surname><given-names>В. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.)., Assoc. Prof., Assoc. Prof. of the Department of Skin and Sexually Transmitted Diseases </p><p>Akademika Lebedeva str., 6, Saint Petersburg, 194044, Russian Federation </p></bio><bio xml:lang="ru"><p>д.м.н., доцент, доцент кафедры кожных и венерических болезней 194044, Российская Федерация, г. Санкт-Петербург, ул. Академика Лебедева, д. 6 </p></bio><email>haric03@list.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Samtsov</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Самцов</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.)., Prof., Head of the Department of Skin and Sexually Transmitted Diseases </p><p>Akademika Lebedeva str., 6, Saint Petersburg, 194044, Russian Federation </p></bio><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой кожных и венерических болезней 194044, Российская Федерация, г. Санкт-Петербург, ул. Академика Лебедева, д. 6 </p></bio><email>avsamtsov@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">S. M. Kirov Military Medical Academy, Ministry of Defence of the Russian Federation</institution></aff><aff><institution xml:lang="ru">Военно-медицинская академия им. С. М. Кирова Министерства обороны Российской Федерации</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-12-26" publication-format="electronic"><day>26</day><month>12</month><year>2019</year></pub-date><volume>95</volume><issue>6</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>14</fpage><lpage>21</lpage><history><date date-type="received" iso-8601-date="2020-01-25"><day>25</day><month>01</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-01-25"><day>25</day><month>01</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, Zhukov A.S., Khairutdinov V.R., Samtsov A.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, Жуков А.С., Хайрутдинов В.Р., Самцов А.В.</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">Zhukov A.S., Khairutdinov V.R., Samtsov A.V.</copyright-holder><copyright-holder xml:lang="ru">Жуков А.С., Хайрутдинов В.Р., Самцов А.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikdv.ru/jour/article/view/528">https://vestnikdv.ru/jour/article/view/528</self-uri><abstract xml:lang="en"><p>In this review, we systematized information in a new direction — precision medicine in the aspect of the study of psoriasis. An idea of relevance, basic concepts is given, a modern classification of biomarkers is given. Examples of each type of biomarker are presented, their role in the diagnosis and treatment of patients. The relationship of a personalized and precise approach to patient management is indicated. The main directions of development of this section of medicine are indicated. </p></abstract><trans-abstract xml:lang="ru"><p>В данном обзоре проведена систематизация сведений по новому направлению — прецизионной медицине в аспекте изучения псориаза. Дано представление об актуальности, базовых понятиях, приведена современная классификация биомаркеров. Представлены примеры каждого типа биомаркера, их роль в диагностике и лечении больных. Указана взаимосвязь персонализированного и прецизионного подхода к ведению пациентов. Обозначены основные направления развития данного раздела медицины. </p></trans-abstract><kwd-group xml:lang="en"><kwd>psoriasis</kwd><kwd>biomarkers</kwd><kwd>precision medicine</kwd><kwd>personalized therapy</kwd><kwd>prognosis</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>биомаркеры</kwd><kwd>прецизионная медицина</kwd><kwd>персонализированная терапия</kwd><kwd>прогноз</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Coates L. C., Murphy R., Helliwell P. S. New GRAPPA recommendations for the management of psoriasis and psoriatic arthritis: process, challenges and implementation. Br J Dermatol. 2016;174(6):1174–1178.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2. Warren R. B., Smith R. L., Campalani E., Eyre S., Smith C. H., Barker J. N. et al. 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