Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov55610.25208/vdv556ArticlesСтатьиResearch ArticleBasalioma: epidemiology, etiology, pathogenesis and clinical picture (part 1)Базально-клеточныи рак кожи: эпидемиология, этиология, патогенез, клиническая картина (часть 1)VolginV NВолгинВ Н

д.м.н., врач

vnvolgin@yandex.ruSokolovaT VСоколоваТ В

профессор кафедры дерматовенерологии

KolbinaM SКолбинаМ С

ассистент кафедры дерматовенерологии

SokolovskayaA AСоколовскаяА А

соискатель кафедры дерматовенерологии

Academician N.N. Burdenko Main Military Clinical Hospital, Russian Defense Ministry GospitalnayaФГКУ «Главный военный клинический госпиталь им. академика Н.Н. Бурденко» Министерства обороны Российской ФедерацииState Institute of Advanced Training for Doctors, Russian Defense MinistryГосударственный институт усовершенствования врачей МО РФ15042013892NO2 (2013)№2 (2013)61411032020Copyright ©; 2013, Volgin V.N., Sokolova T.V., Kolbina M.S., Sokolovskaya A.A.Copyright ©; 2013, Волгин В.Н., Соколова Т.В., Колбина М.С., Соколовская А.А.2013Volgin V.N., Sokolova T.V., Kolbina M.S., Sokolovskaya A.A.Волгин В.Н., Соколова Т.В., Колбина М.С., Соколовская А.А.https://creativecommons.org/licenses/by/4.0https://vestnikdv.ru/jour/article/view/556

The authors present literature data related to the epidemiology, etiology, pathogenesis and clinical course of basalioma. The key classifications are given. As many as 62 references are reviewed.

Представлены данные литературы по эпидемиологии, этиологии, патогенезу и клиническому течению базальноклеточного рака кожи (БКРК). Приведены основные классификации БКРК. Представлен анализ 62 источников литературы.

basaliomacancerogensionizing radiationradiationblood groupsclassificationsparticular features of the clinical pictureбазально-клеточный рак кожи (БКРК)канцерогеныионизирующее излучениерадиациягруппы кровиклассификацииособенности клиникиRusak Y.E. Dermatooncology. Surgut: SurGU; 2007. [Русак Ю.Э. Дерматоонкология. Сургут: СурГУ; 2007].Roewert-Huber J., Lange-Asschenfeldt B., Stockfleth E. et al. Epidemiology and aetiology of basal cell carcinoma. Br J Dermatol 2007; 2: 47—51.Zlokachestvennye novoobrazovaniya v Rossii v 2007 godu (zabolevaemost' i smertnost') / Pod. red. V.I. Chissova, V.V. Starinskogo, G.V. Petrovoy. M.: FGU «MNIOI im. P.A. Gertsena Rosmed — tekhnologiy»; 2009Malishevskaja N.P., Bakurov E.A. Rol' i zadachi kozhno-venerologicheskih uchrezhdenij v organizacii rannego vyjavlenija zlokachestvennyh novoobrazovanij kozhi. Tez. nauch. rab. H Vseros. s#zda dermatovenerologov. Moskva; 2008: 8—9Kubanova A.A., Martynov A.A. Malignant skin neoplasms in the structure of oncological morbidity in the Russian Federation. Vestn Dermatol Venerol l 2007; 6: 19—24.Organizatsionnaya tekhnologiya vzaimodeystviya kozhno-venerologicheskoy i onkologicheskoy sluzhb po okazaniyu spetsializirovannoy pomoshchi bol'nym s predopukholevoy i zlokachestvennoy patologiey kozhi. Min. zdrav. RF, metod. ukaz. № 2003/60. M 2003.Romanko Yu.S., Kaplan M.A., Popuchiev V.V. Basal cell carcinoma of the skin: the problems of treatment and the current aspects of photodynamic therapy. Russian J Skin Venereal Dis 2004; 6: 6—10.Dubenskij V.V., Garmonov A.A. Sovremennye aspekty jepidemiologii, patogeneza, kliniki i lechenija bazal'no-kletochnogo raka kozhi. Vestn dermatol i venerol 2004; 6: 7—12.Chissov V.l., Starinskiy V.V., Petrova G.V. Zlokachestvennye novoobrazovaniya v Rossii v 2003 godu (zabolevaemost' i smertnost'). M 2005.Bogush P.G., Bogush I.G., Selisskij G.D., Umerenkov M.G. Dermatoonkologicheskaja pomoshh' naseleniju: aktual'nye zadachi. Vestn Dermatol Venerol 2003; 6: 7—9.Cancer statistics. CA. 1989; 39: 3—20.Kunte C., Konz B. Current recommendations in the treatment of basal cell carcinoma and squamous cell carcinoma of the skin. Hautarzt 2007; 58 (5): 419—426.Northington M., Tamburin L., Hamza S. et al. Giant basal cell carcinoma associated with human papillomaviruses infection. J Cutan Patol 2004; 31: 174— 178.Lorenzini M., Gatti S., Giannitrapani A. Giant basal cell carcinoma of the thoracie wall: a case report and review of the literature. Br J Plast Surg 2005; 58: 1007—1010.Hlebnikova A.N., Kazanceva I.A. Gistologicheskie varianty bazal'no-kletochnogo raka kozhi. Russian Journal of Skin and Sexually Transmitted Diseases 2000; 2: 4—8.Evropejskoe rukovodstvo po lecheniju dermatologicheskih boleznej. Per. s angl.; Pod red. A.D. Kacambasa, T.M. Lotti. Moskva: MEDpress-inform; 2008.Bower C.P., Lear J.T., de Berker D.A. Basal cell carcinoma follow-up practices by dermatologists: a national survey. Br J Dermatol 2001; 145(6): 949—956.Lai S.Y., Weber R.S. High-risk non-melanoma skin cancer of the head andneck. Curr Oncol Rep USA 2005; 7 (2): 154—158.Bujko A.S., Safronenkova I.A., Piterova O.V. Jepitelial'nye zlokachestvennye opuholi kozhi vek stadii T3—4: kombinirovannoe lechenie ili skal'pel'? Oftal'mol zhurn 2002; 1: 30—34.Durnov L.A., Gromov G.B., Chernova N.V. i dr. Zlokachestvennye opuholi kozhi u detej. Posobie dlja vrachej. Moskva: Medicina; 2003.Evtushenko V.A. Fotodinamicheskaja terapija s fotoditazinom bol'nyh bazal'no-kletochnym rakom kozhi i tjazhelymi soputstvujushhimi zabolevanijami. Ros Bioter zhurn 2007; 1: 15.Hlebnikova A.N. Sluchaj bazal'no-kletchnogo raka kozhi u devochki 15 let. Mater. nauch.-prakt. konf.: Aktual'nye problemy dermatoonkologii. M; 2002: 138—139.Sokolova T.V. Sklerodermopodobnaja bazalioma u molodoj devushki. Aktual. vopr. teor. i prakt. med. Ul'janovsk; 1995: 188—189.Pisklakova T.P. K voprosu o klassifikacii bazal'no-kletochnogo raka kozhi II Mater, nauch.-prakt. konf.: Aktual'nye problemy dermatoonkologii. M. 2002: 93—94.Snarskaja E.S., Molochkov V.A. Bazalioma. M; 2003: 55—83.Kim M.Y., Park H.J., Back S.C. Mutations of the p53 and PTCH gene in basal cell carcinomas: UV mutation signature and strand bias. J. Dermatol. Sci. 2002; 29: 1—9.Vereecken P., Da Costa C.M., Steels E. et al. Fluorescence diagnosis of face-located basal cell carcinomas: a new dermatological procedure which may help the surgeon. Acta Chir. Belg. Belgium. 2007; 107(2): 205—207.Volgin V.N., Sokolova T.V. Rol' nekotoryh jekzogennyh i jendogennyh faktorov v formirovanii bazal'no-kletochnogo raka kozhi. Voen.med. zhurn. 2008; 12: 52—53.Volgin V.N., Sokolova T.V., Gluhova S.I. Rol' grupp krovi sistemy AV0 dlja otbora specialistov s uchetom dejstvija professional'nyh vrednostej. Mater. V nauch. prakt. konf. pamjati prof. A.L. Mashkillejsona. M. 2008: 13—15.Lavrov N.N. Zdorov'e zhenshhiny i 4 gruppy krovi. Rostov-na-Donu: Feniks; 2004. [Лавров Н.Н. Здоровье женщины и 4 группы крови. Ростов-на-Дону: Феникс; 2004].Reifenberger J., Wolter M., Knobbe S.B. Somatic mutations in PTCH, SMON, SUFUH and TP53 genes in sporadic basal cell carcinomas. Br J Dermatol 2005; 152: 43—51.Tursen U., Tifik E., Unal S. et al. Relationship between AB0 blood groups and skin cancer. Dermatol Online J 2001; 11(3): 44—49.Smirnova I.O. Kolichestvo tuchnyh kletok i jekspressija involjukrina pri starenii kozhi. Problemy ukreplenija zdorov'ja i profilaktika zabolevanij: Mater. nauch. prakt. konf. SPb GMA. M; 2004: 270.Akimov V.G. Biological effects of ultraviolet skin irradiation Vestn Dermatol Venerol 2008; 3: 81—85.Dubensky V.V., Dubensky VL.V. Skin neoplasms in dermatovenerological practice. Problems of epidemiology, etiopathogenesis and diagnostics Vestn Dermatol Venerol 2008; 6: 22—40.Dissemond J., Grabbe S. Non-surgical therapy of basal cell carcinoma of the head-neck region. Laryngorhinootologie. Germany. 2006; 85 (2): 133—141.Galil-Ogly G., Molochkov V.A., Sergeev Ju.V. Dermatoonkologija. Moskva: Medicina dlja vseh; 2005.Vul'f K., Dzhonson R., Sjurmond D. Dermatologija po T. Ficpatriku (atlas-spravochnik). Izd. 2-e. Moskva: Praktika; 2007.Rass K., Tilgen W. Treatment of melanoma and nonmelanoma skin cancer. Adv Exp Med Biol Germany 2008; 624: 296—318.Panova I.E., Vazhenin A.V., Usova R.A. i dr. Jepidemiologija, kliniko-morfologicheskaja harakteristika, differencial'naja diagnostika bazal'no-kletochnogo raka kozhi vek. Uchebnoe posobie. Cheljabinsk; 2003: 34.Dubenskij V.V., Vavilov A.M., Garmonov A.A. i dr. Opuholi kozhi. Klinicheskaja dermatovenerologija. Pod red. Ju.K. Skripkina, Ju.S. Butova. Moskva: GJeOTAR-Media; 2009.Mutovin G.R. Osnovy klinicheskoj genetiki. Moskva: Vysshaja shkola; 2001.Smulevich V.B., Solenova L.G., Beljakova S.V. Professija roditelej kak faktor onkologicheskogo riska u detej. Ros onkol zhurn 2001; 4: 45—47.Malishevskaja N.P., Selisskij G.D., Molochkov V.A. i dr. Rol' fizicheskih promyshlenno-jekologicheskih faktorov v razvitii patologii kozhi. Vestn Dermatol Ven-erol 1999; 2: 25—28.Dubenskij V.V., Red'ko R.V., Garmonov A.A. Novoobrazovanija kozhi v praktike dermatovenerologov. Pod red. V.V. Dubenskogo. Tver': izd-vo Triada; 2002.Snarskaya Ye.S., Suchkov S.V. Pathogenesis of basaliomas: Immunological aspects Rus J of skin and sexually transmitted diseases 2004; 2: 4—9.Lo Muzio L. Nevoid basal cell carcinoma syndrome (Gorlin syndrome). Orphanet J. Rare Dis. Italy. 2008; 3: 32.Apatenko A.K. Jepitelial'nye opuholi i poroki razvitija kozhi. Moskva: Medicina; 1973.Lever W.F., Shaumburg-Lever G. Histopathology of the skin. 7-th eds. Lippincott. Philadelphia; 1990.Moroni M, Veronese S, Benvenuti S et al. Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study. Lancet Oncol. 2005 May; 6(5): 279—86.Rajchev R., Andreev V. Oshibki diagnostiki i lechenija zlokachestvennyh opuholej. Sofija: Medicina i fizkul'tura; 1964.Volgin V., Sokolova T. Basal-cell carcinoma of the skin under the present-day conditions. Vrach. 2009; 2: 6—9.Vazhenina D.A., Vasil'ev S.A., Dudnik S.N. i dr. Recidivirujushhij bazal'no-kletochnyj rak kozhi vek (osobennosti klinicheskogo techenija, lechenie). Ros. Med. zhurn. 2006; 11: 36—43.Sergeev Ju.V., Borisova S.V., Shubina, S.I. Aktual'nye problemy prakticheskoj dermatoonkologii: rost zabolevaemosti, sovershenstvovanie dispanserizacii i profilaktika bazal'no-kletochnogo raka kozhi. Russian Journal of Skin and Sexually Transmitted Diseases 1999; 2: 4—9.Handa Y. Multiple pigmented basal cell carcinomas arising in the normal-appearing skin after radiotherapy for carcinoma of the cervix. Dermatol Surg 2003; 12: 1233—1235.Jurin A.G. Kriterii diagnostiki i pravila registracii zlokachestvennyh i dobrokachestvennyh pervichno-mnozhestvennyh opuholej. Vopr onkol 2003; 3: 376—382.Suhova T.E., Tret'jakova E.I., Hlebnikova A.N. i dr. Opyt lechenija pervichnoj i recidivirujushhej bazaliomy v Moskovskoj oblasti. Moskovskij nauchno — issledovatel'skij klinicheskij institut im. M.F. Vladimirskogo. Nauchno — prakticheskaja konferencija: Aktual'nye voprosy terapii infekcij, peredavaemyh polovym putem i hronicheskih dermatozov. Tezisy nauchnyh rabot. Ekaterinburg 2002.Hahn H. Mutations of the human homolog of drosophila patched in the nevoid basal cell carcinoma syndrome. 1996; 85: 841—851.Chung С.Н. Nevoid basal cell carcinoma syndrome — clinical manifestations and mutation analysis of a Taiwanese family. 2003; 11: 793—797.Tret'jakova E.I., Molochkov V.A., Pisklakova T.P. i dr. Osobennosti sistemy HLA u bol'nyh s mnozhestvennymi bazaliomami kozhi i sindromom Gorlina — Gol'tca. Russian Journal of Skin and Sexually Transmitted Diseases 2000; 2: 11—17.Molochkov V.A. Rak kozhi pri geneticheskih kozh-nyh sindromah. Russian Journal of Skin and Sexually Transmitted Diseases 2000; 3: 4—14.Denisov A.P. Pervichno-mnozhestvennyj rak i zlokachestvennye opuholi. Klin Med 1995; 5: 65—67.