Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov62610.25208/vdv626ArticlesСтатьиResearch ArticleZinc, its biological role and use in dermatologyЦинк, его биологическая роль и применение в дерматологииKHLEBNIKOVAA NХЛЕБНИКОВАА Н

д.м.н., профессор кафедры кожных и венерических болезней

PETRUNIND DПЕТРУНИНД Д

к.м.н., медицинский советник

I.M. Sechenov First Moscow State Medical UniversityГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава РоссииRepresentative Office ot Astellas Pharma Europe B.VПредставительство компании «Астеллас Фарма Юроп Б.В.»15122013896NO6 (2013)№6 (2013)10011611032020Copyright ©; 2013, KHLEBNIKOVA A.N., PETRUNIN D.D.Copyright ©; 2013, ХЛЕБНИКОВА А.Н., ПЕТРУНИН Д.Д.2013KHLEBNIKOVA A.N., PETRUNIN D.D.ХЛЕБНИКОВА А.Н., ПЕТРУНИН Д.Д.https://creativecommons.org/licenses/by/4.0https://vestnikdv.ru/jour/article/view/626

This literature review detines the biological role ot zinc in the human body, immune homeostasis and skin physiology as well as pathophysiology ot skin diseases. It describes the current range ot systemic and topical zinc preparations and their pharmacological characteristics. The review also describes skin diseases that may be treated with the use ot zinc preparations on a grounded basis, and discloses the clinical experience ot the use ot these drugs described in the world literature. It sets out certain recommendations tor using zinc preparations in clinical practice.

В обзоре литературы охарактеризована биологическая роль цинка в организме человека, иммунном гомеостазе и физиологии кожи, а также в патофизиологии кожных болезней. Описан существующий спектр системных и местных препаратов цинка, приведены их фармакологические характеристики. Охарактеризованы кожные болезни, при которых применение препаратов цинка может иметь основания, и освещен клинический опыт использования данных препаратов, описанный в международной литературе. Сформулированы некоторые рекомендации по применению препаратов цинка в клинической практике.

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