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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Vestnik dermatologii i venerologii</journal-id><journal-title-group><journal-title xml:lang="en">Vestnik dermatologii i venerologii</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник дерматологии и венерологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0042-4609</issn><issn publication-format="electronic">2313-6294</issn><publisher><publisher-name xml:lang="en">Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">635</article-id><article-id pub-id-type="doi">10.25208/vdv635</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Antibiotic resistance of P. acnes in the treatment of acne. Ways for solving the problem</article-title><trans-title-group xml:lang="ru"><trans-title>Антибиотикорезистентность P. acnes в терапии акне. Пути решения проблемы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>MURASHKIN</surname><given-names>N N</given-names></name><name xml:lang="ru"><surname>МУРАШКИН</surname><given-names>Н Н</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры инфекционных болезней и эпидемиологии с курсом дерматовенерологии</p></bio><email>m_nn2001@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Krasnodar Municipal Medical Institute of Higher Education for Nurses</institution></aff><aff><institution xml:lang="ru">МАОУ ВПО Краснодарский муниципальный медицинский институт высшего сестринского образования</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2013</year></pub-date><volume>89</volume><issue>6</issue><issue-title xml:lang="en">NO6 (2013)</issue-title><issue-title xml:lang="ru">№6 (2013)</issue-title><fpage>128</fpage><lpage>131</lpage><history><date date-type="received" iso-8601-date="2020-03-11"><day>11</day><month>03</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, MURASHKIN N.N.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, МУРАШКИН Н.Н.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">MURASHKIN N.N.</copyright-holder><copyright-holder xml:lang="ru">МУРАШКИН Н.Н.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikdv.ru/jour/article/view/635">https://vestnikdv.ru/jour/article/view/635</self-uri><abstract xml:lang="en"><p>The author describes the reasons and frequency of antibiotic resistance of P. acnes in acne patients. He reviews the strategy and methods for doctors to inhibit the prevalence of antibiotic resistance of P. acnes. The article discusses the important role of benzoyl peroxide and synergistic effect of the combination of adapalene and benzoyl peroxide in the finished form to overcome the antibiotic resistance of P. acnes and ensure the treatment efficacy.</p></abstract><trans-abstract xml:lang="ru"><p>Представлены причины и частота развития резистентности P. acnes к антибиотикотерапии у больных акне. Рассмотрены стратегия и тактика врача по ограничению распространения антибиотикорезистентности P. acnes. Обсуждается важная роль бензоила пероксида и синергетический эффект готовой комбинации адапален/бензоила пероксид в преодолении устойчивости P. acnes и достижении эффективности лечения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>P. acnes</kwd><kwd>antibiotic resistance</kwd><kwd>P. acnes</kwd><kwd>benzoyl peroxide</kwd><kwd>adapalene</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>антибиотикорезистентность</kwd><kwd>бензоила пероксид</kwd><kwd>адапален</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Самцов A.В. Aкне и акнеформные дерматозы. М: ЮТКОМ, 2009; 288</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Burkhart C., Burkhart C. Expanding the microcomedone theory and acne therapeutic: P. acnes biofilm produses biological glue that holds corneocytes together to form plug. J Am Acad Dermatol 2007; 67: 722—744.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Webster G.F. 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