Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov77310.25208/vdv773ArticlesСтатьиCurrent approaches to diagnostics of mycosis fungoidesСовременные подходы к диагностике грибовидного микозаBrattsevaE VБратцеваЕ В

аспирант; ФГУ «ГНЦД Росмедтехнологий»

brattseva_k@mail.ruRotanovS VРотановС В

доцент, ведущий научный сотрудник отдела лабораторной диагностики ИППП и болезнейкожи; д.м.н; ФГУ «ГНЦД Росмедтехнологий»

BratsevaE VRotanovS VФГУ «ГНЦД Росмедтехнологий»15122010866NO6 (2010)№6 (2010)162211032020Copyright ©; 2010, Brattseva E.V., Rotanov S.V., Bratseva E.V., Rotanov S.V.Copyright ©; 2010, Братцева Е.В., Ротанов С.В., Bratseva E.V., Rotanov S.V.2010Brattseva E.V., Rotanov S.V., Bratseva E.V., Rotanov S.V.Братцева Е.В., Ротанов С.В., Bratseva E.V., Rotanov S.V.https://creativecommons.org/licenses/by/4.0https://vestnikdv.ru/jour/article/view/773

The authors describe strong and weak sides of current methods for diagnostics of mycosis fungoides. Diagnostics of mycosis fungoides is mainly based on the clinical presentation of this disease, which is a significant problem for a dermatovenerologist, especially at early stages of the disease when rashes are of different types. Laboratory methods used to confirm the diagnosis are microscopic examination and immunophenotypic analysis of skin biopsy samples from the affected region as well as determination of clonality of T-lymphocytes in the skin using the PCR method.

Рассмотрены преимущества и недостатки современных методов диагностики грибовидного микоза. Диагностика грибовидного микоза основывается главным образом на клинической картине заболевания, что представляет значительные трудности для врача-дерматовенеролога, особенно на ранних его стадиях, когда высыпания отличаются большим разнообразием. Лабораторными методами подтверждения диагноза являются гистологическое и иммунофенотипическое исследования биоптатов кожи из области поражения, а также определение клональности Т-лимфоцитов в коже методом полимеразной ценной реакции.

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