Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov83610.25208/vdv836ArticlesСтатьиExternal glucocorticosteroids: selection criteria in terms ofefficacy and safetyНаружные глюкокортикостероидные препараты:критерии выбора с позиции эффективностии безопасностиBelousovaT AБелоусоваТ А

доцент кафедры дерматовенерологии лечебного факультета; к.м.н; Первый Московский государственный медицинский университет им. И.М. Сеченова

belka-1147@mail.ruGoryachkinaM VГорячкинаМ В

сотрудник лаборатории по изучению репаративных процессов в коже; к.м.н; НИИ молекулярной медицины Первого Московского государственного медицинского университетаим. И.М. Сеченова

belka-1147@mail.ruBelousovaT AGoryachkinaM VПервый Московский государственный медицинский университет им. И.М. СеченоваНИИ молекулярной медицины Первого Московского государственного медицинского университетаим. И.М. Сеченова15122010866NO6 (2010)№6 (2010)9310011032020Copyright ©; 2010, Belousova T.A., Goryachkina M.V., Belousova T.A., Goryachkina M.V.Copyright ©; 2010, Белоусова Т.А., Горячкина М.В., Belousova T.A., Goryachkina M.V.2010Belousova T.A., Goryachkina M.V., Belousova T.A., Goryachkina M.V.Белоусова Т.А., Горячкина М.В., Belousova T.A., Goryachkina M.V.https://creativecommons.org/licenses/by/4.0https://vestnikdv.ru/jour/article/view/836

The article describes mechanisms of action as well as indications and adverse effects of topical glucocorticosteroids. It examines the pharmacological and pharmacokinetic properties of fluticasone propionate, an efficient external glucocorticosteroid having a high safety level and good cosmetic properties. The data of controlled Russian and international studies of the efficacy and safety of fluticasone propionate for the treatment of psoriasis, atopic dermatitis and eczema.

Обсуждаются механизмы действия, показания к применению и побочные эффекты наружных глюкокортикостероидных препаратов. Рассматриваются фармакологические и фармакокинетические свойства флутиказона пропионата - эффективного наружного глюкокортикостероида с высоким уровнем безопасности и хорошими косметическими свойствами. Приводятся данные контролируемых отечественных и зарубежных исследований эффективности и безопасности применения флутиказона пропионата в терапии псориаза, атопического дерматита и экземы.

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