Vestnik dermatologii i venerologiiVestnik dermatologii i venerologiiВестник дерматологии и венерологии0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov97210.25208/vdv972ArticlesСтатьиThe use of topic antibiotics for treatment of acneТОПИЧЕСКИЕ АНТИБИОТИКИ В ЛЕЧЕНИИ АКНЕSamtsovA VCамцовА В

начальник кафедры кожных и венерических болезней, профессор; ФГОУ ВПО «Военно-медицинская академия им. С.М. Кирова МО РФ»

avsamtsov@mail.ruФГОУ ВПО «Военно-медицинская академия им. С.М. Кирова МО РФ»15022011871NO1 (2011)№1 (2011)848511032020Copyright ©; 2011, Samtsov A.V.Copyright ©; 2011, Cамцов А.В.2011Samtsov A.V.Cамцов А.В.https://creativecommons.org/licenses/by/4.0https://vestnikdv.ru/jour/article/view/972

The article contains the literature data concerning the efficacy and safety of topic antibiotics for treatment of acne. The results of studies investigating the efficacy of clindamycin external formulations in patients with acne are shown.

Приведены данные литературы об эффективности и безопасности использования топических антибиотиков в лечении акне. Представлены результаты исследований по изучению эффективности применения у больных акне наружных форм клиндамицина.

AcneExternal therapyClindamycinакненаружная терапияклиндамицинStrauss J., Krowchuk D., Leyden G. et al. Guidelines of care for acne vulgaris management. J Am Acad Dermatol 2007; 56: 651-663.Самцов А.В. Акне и акнеформные дерматозы. М., 2009: 287.Thiboutot D., Gollnick H. New insights into the management of acne: an update from the Global Alliance to improve outcomes in acne group. J Am Acad Dermatol 2009; 60: 1-50.Ross J., Eady E., Jonathan H. et al. Clinical Resistance to Erythromycin and Clindamycin in Cutaneous Propionibacteria Isolated from Acne Patients Is Associated with Mutations in 23S rRNA. Antimicrobial agents and Chemotherapy 1997; 5: 1162-1165.Kuhlman D.S., Callen J.P. A comparison of clindamycin phosphate 1 percent topical lotion and placebo in the treatment of acne vulgaris. Cutis 1986; 38: 203-206.Katsambas A., Towarky A.A., Stratigos J. Topical clindamycin phosphate compared with oral tetracycline in the treatment of acne vulgaris. Br J Dermatol 1987; 116: 387-391.Leyden J. Cutis 2002. Leyden J.J. Effect of topical benzoyl peroxide/clindamycin versus topical clindamycin and vehicle in the reduction of Propionibacterium acnes. Cutis. 2002 Jun; 69 (6): 475-80.Wolf J., Kaplan D., Kraus S. et al. Efficacy and tolerability of combined topical treatment of acne vulgaris with adapalene and clin- damycin: a multicenter, randomized, investigator-blinded study 1. JAAD; 49 (3); 211-217.Lookingbill D., Chalker D., Lindholm et al. Treatment of acne with a combination clindamycin/benzoil peroxide gel compared with clindamycin gel, benzoyl peroxide gel and vehicle gel J Am Acad Dermatol 1997; 37: 590-595.Leyden J.J., Hickman J.G., Jarratt M.T., Stewart D.M., Levy S.F. The efficacy and safety of a combination benzoyl peroxide/clindamycin topical gel compared with benzoyl peroxide alone and a benzoyl peroxide/erythromycin combination product. J Cutan Med Surg. 2001 Jan-Feb; 5 (1): 37-42.Alirezai M., Gerlach B., Horvath A., Forsea D., Briantais P., Guyomar. Results of a randomised, multicentre study comparing a new water-based gel of clindamycin 1% versus clindamycin 1% topical solution in the treatment of acne vulgaris. Eur J Dermatol 2005 Jul- Aug; 15(4): 274-8.Del Rosso J., Schmidt N. A review of the anti-inflammatory properties of clindamycin in the treatment of acne vulgaris. Cutis 2010; 85: 15-24.Shahlita A.R., Smith E.B., Bauer E. Topical erythromycin v clindamycin therapy for acne. A multicenter, double-blind comparison. Arch Dermatol. 1984 Mar; 120 (3): 351-5.