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Personalized approach to the selection of therapy for patients with psoriasisbased on the results of molecular and genetic tests
- Authors: Znamenskaya LF1, Frigo NV1, Rotanov SV1, Volkov IA1, Volnukhin VA1, Zhilova MB1
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Affiliations:
- Issue: Vol 86, No 5 (2010)
- Pages: 77-83
- Section: Articles
- URL: https://vestnikdv.ru/jour/article/view/961
- DOI: https://doi.org/10.25208/vdv961
- ID: 961
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Abstract
and phototherapy with the use of molecular and genetic technologies. The authors revealed that the predictor of evident clinical
response to treatment of psoriasis patients with Infliximab is the homozygous TT genotype at the 676 locus of exon 6 of the TNFR-
II gene; predictors of high efficacy and safety of treatment of psoriasis patients with Infliximab with the use of ultraviolet therapy
(PUVA and mid-wavelength ultraviolet therapy (311 nm)) are: heterozygous GA genotype at the 19007 locus of the ERCC gene
and homozygous CC genotype at the 27945 locus of the XPF gene.
About the authors
L F Znamenskaya
Email: znaml@cnikvi.ru
N V Frigo
S V Rotanov
I A Volkov
V A Volnukhin
M B Zhilova
References
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Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).