Purulent Hidradenitis. Part I

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Abstract

Until recently, the pathogenesis of purulent hidradenitis was a little- and sporadically studied issue, which invariably created difficulties in the therapeutic treatment of this disease. Its often severe recurrency rate, high incidence and the lack of effective treatment have predetermined the urgency of the problem and raised the scientific and practical interest in this field among the scientists worldwide. Recent data indicate a significant role of damage-associated molecular patterns (DAMP) and the activation of congenital immunity, associated with Th17 lymphocytes, in the development of inflammatory disease. Likewise, the violation of the transmission of the cellular Notch signaling pathway plays an important role in the development of purulent hidradenitis. 

About the authors

A. N. Rodionov

North-Western State Medical University named after I. I. Mechnikov of the Ministry of Health of Russian Federation, St. Petersburg

Author for correspondence.
Email: fake@neicon.ru
Piskarevsky prospect, 47, 195067 Russian Federation

S. V. Skrek

North-Western State Medical University named after I. I. Mechnikov of the Ministry of Health of Russian Federation, St. Petersburg; The Pierre Wolkenstein French Dermatological Clinic, St. Petersburg

Email: fake@neicon.ru

Piskarevsky prospect, 47, 195067

Ryleeva str., 24, 191123

Russian Federation

A. V. Sobolev

Research Institute of Medical Mycology named after P. N. Kashkin, North-Western State Medical University named after I. I. Mechnikov of the Ministry of Health of Russian Federation, St. Petersburg

Email: fake@neicon.ru
Santiago de Cuba str., 1/28, 194291 Russian Federation

A. A. Yunovidova

The Pierre Wolkenstein French Dermatological Clinic, St. Petersburg

Email: fake@neicon.ru
Ryleeva str., 24, 191123 Russian Federation

L. R. Chernova

The Pierre Wolkenstein French Dermatological Clinic, St. Petersburg

Email: fake@neicon.ru
Ryleeva str., 24, 191123 Russian Federation

P. Wolkenstein

Dermatological Service of the Henri Mondor University Hospital, Créteil

Email: fake@neicon.ru
Avenue du Maréchal de Lattre de Tassigny, 51, 94000 France

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Copyright (c) 2017 Rodionov A.N., Skrek S.V., Sobolev A.V., Yunovidova A.A., Chernova L.R., Wolkenstein P.

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