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Cutaneous sinus histiocytosis of face of the non-Langerhans cell histiocytoses type (cutaneous Rosai — Dorfman disease)
- Authors: Sokolovsky E.V.1, Mikheev G.N.1, Rybakova M.G.1, Manasheva E.B.1, Seredina V.A.1
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Affiliations:
- Pavlov First Saint Petersburg State Medical University, Ministry of Health of the Russian Federation
- Issue: Vol 94, No 5 (2018)
- Pages: 66-71
- Section: CLINICAL CASE REPORTS
- URL: https://vestnikdv.ru/jour/article/view/441
- DOI: https://doi.org/10.25208/0042-4609-2018-94-5-66-71
- ID: 441
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Abstract
An extremely rare case of sinus histiocytosis of the non-Langerhans cell histiocytoses type is described in 55-year-old patient with isolated localization of cutanious lesion on the right cheek without involvement of nodular structures. Main skin lesion was an erythematous-cyanotic node with multiple milia-like lesions on the top of it. Histologically revealed feature was a large number of plasma cells, besides phenomenon of emperipolesis was described, which was first falsely perceived by pathologists as phagocytosis. In immu-nohistochemistry assay the changes were characterized by proliferation of large polygonal histiocytes with accumulation of pentalamellar markers in its cytoplasm (protein S-100, CD68).
About the authors
E. V. Sokolovsky
Pavlov First Saint Petersburg State Medical University, Ministry of Health of the Russian Federation
Email: fake@neicon.ru
Evgeny V. Sokolovsky — Dr. Sci. (Med.), Prof., Head of Department, Department of Dermatovenereology with a Hospital.
L'va Tolstogo str., bldng 6-8, Saint Petersburg, 197022
Russian FederationG. N. Mikheev
Pavlov First Saint Petersburg State Medical University, Ministry of Health of the Russian Federation
Email: fake@neicon.ru
Georgy N. Mikheev — Cand. Sci. (Med.), Ass. Prof., Department of Dermatovenereology with a Hospital.
L'va Tolstogo str., bldng 6-8, Saint Petersburg, 197022
Russian FederationM. G. Rybakova
Pavlov First Saint Petersburg State Medical University, Ministry of Health of the Russian Federation
Email: fake@neicon.ru
Маrgarita G. Rybakova — Dr. Sci. (Med.), Prof., Head of the Department, Department of Pathological Anatomy with a Pathoanatomical Department.
L'va Tolstogo str., bldng 6-8, Saint Petersburg, 197022
Russian FederationE. B. Manasheva
Pavlov First Saint Petersburg State Medical University, Ministry of Health of the Russian Federation
Author for correspondence.
Email: volf8989@mail.ru
Elizaveta B. Manasheva — Medical Resident, Department of Dermatovenereology with a Hospital.
L'va Tolstogo str., bldng 6-8, Saint Petersburg, 197022
Russian FederationV. A. Seredina
Pavlov First Saint Petersburg State Medical University, Ministry of Health of the Russian Federation
Email: fake@neicon.ru
Vera A. Seredina — Dermatovenerologist, Dermatovenereological Hospital.
L'va Tolstogo str., bldng 6-8, Saint Petersburg, 197022
Russian FederationReferences
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