Опыт применения наружных средств косметической линии Эмолиум в комплексной терапии детей, больных атопическим дерматитом
- Авторы: ТЕКУЧЕВА ЛВ1, ЗНАМЕНСКАЯ ЛФ1
-
Учреждения:
- ФГУ «ГНЦДК Минздравсоцразвития России»
- Выпуск: Том 87, № 2 (2011)
- Страницы: 71-77
- Раздел: Статьи
- Дата подачи: 11.03.2020
- Дата публикации: 15.04.2011
- URL: https://vestnikdv.ru/jour/article/view/1003
- DOI: https://doi.org/10.25208/vdv1003
- ID: 1003
Цитировать
Полный текст
Аннотация
Обобщены современные данные о функции эпидермального барьера, механизмах его нарушения и роли в развитии атопического дерматита. Представлены результаты, подтверждающие эффективность комплексного применения средств базового ухода в терапии детей, больных атопическим дерматитом. Для базового ухода использовались косметические средства линии Эмолиум в форме крема, эмульсии, а также средства гигиены кожи (эмульсия для ванн, кремовый гель для умывания).
Об авторах
Л В ТЕКУЧЕВА
ФГУ «ГНЦДК Минздравсоцразвития России»
Email: detstvo@cnikvi.ru
старший научный сотрудник отделения детской дерматологии, к.м.н; ФГУ «ГНЦДК Минздравсоцразвития России»
Л Ф ЗНАМЕНСКАЯ
ФГУ «ГНЦДК Минздравсоцразвития России»заведующая отделом дерматологии, к.м.н; ФГУ «ГНЦДК Минздравсоцразвития России»
Список литературы
- Bieber T. Atopic dermatitis. N Engl J Med 2008; 358: 1483-1494.
- Simpson C.R., Newton J., Hippisley-Cox J. et al. Trends in the epidemiology and prescribing of medication for eczema in England. J R Soc Med 2009; 102: 108-117.
- Levy R.M., Gelfand J.M., Yan A.C. The epidemiology of atopic dermatitis. Clin Dermatol 2003; 21: 109-115.
- Schmitt J., Bauer A., Meurer M. Atopic eczema in adulthood. Hautarzt 2008; 59: 841-850.
- Hanifin J.M., Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol (Suppl) 1980; 92: 44-47.
- Akdis C., Akdis M., Bieber T. et al. Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology / American Academy of Allergy, Asthma and Immunology / PRACTALL Consensus Report. J Allergy Clin Immunol 2006;118:152-169.
- Novak N., Bieber T., Leung D. Immune mechanisms leading to atopic dermamitis. J Allegy Clin Immunol 2003; 112: 128-139.
- Cork M.J., Danby S.G., Vasilopoulos Y. et al. Epidermal barrier dysfunction in atopic dermatitis. J Invest Dermatol 2009; 129: 1892-1908.
- Leung D.Y. Our evolving understanding of the functional role of filaggrin in atopic dermatitis. J Allergy Clin Immunol 2009; 124: 494-495.
- Elias P. Stratum corneum defensive functions: an integrated view. J Invest Dermatol 2005; 125: 183-200.
- Palmer C.N., Irvine A.D., Terron-Kwiatkowski A. et al. Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet 2006; 38: 441-446.
- Sandilands A., O'Regan G.M., Liao H. et al. Prevalent and rare mutations in the gene encoding filaggrin cause ichthyosis vulgaris and predispose individuals to atopic dermatitis. J Invest Dermatol 2006; 126: 1770-1775.
- Palmer C.N., Ismail T., Lee S.P. et al. Filaggrin null mutations are associated with increased asthma severity in children and young adults. J Allergy Clin Immunol 2007; 120: 64-68.
- Barker J.N., Palmer C.N., Zhao Y. et al. Null mutations in the filaggrin gene (FLG) determine major susceptibility to early-onset atopic dermatitis that persists into adulthood. J Invest Dermatol 2007; 127: 504-507.
- Stemmler S., Parwez Q., Petrasch-Parwez E. et al. Two common loss-of-function mutations within the filaggrin gene predispose for early onset of atopic dermatitis J. Invest. Dermatol. 2007: 127: 722-724.
- Weidinger S., Illig T., Baurecht H., Irvine A.D., Rodriguez E., Diaz- Lacava A. et al. Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations J Allergy Clin Immunol 2006; 118: 214-219.
- Irvine A. D. Fleshing out filaggrin phenotypes. J Invest Dermatol 2007; 127: 504-507.
- Brown S. J., Sandilands A., Zhao Y. et al. Prevalent and low frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema J Invest Dermatol 2008; 128: 1591-1594.
- Marenholz I., Nickel R., Ruschendorf F. et al. Filaggrin loss-of- function mutations predispose to phenotypes involved in the atopic march. J Allergy Clin Immunol 2006; 118: 866-871.
- Ruether A., Stoll M., Schwarz T. et al. Filaggrin loss-of-function variant contributes to atopic dermatitis risk in the population of Northern Germany. Br J Dermatol 2006; 155: 1093-1094.
- Akiyama M. FLG mutations in ichthyosis vulgaris and atopic eczema: spectrum of mutations and population genetics British Journal of Dermatology 2010; 162: 472-477.
- Zhang X., Liu S., Chen X. et al. Novel and Recurrent Mutations in the Filaggrin Gene in Chinese Patients with Ichthyosis Vulgaris British Journal of Dermatology. Accepted Date: 19-Feb-2010.
- Ong P.Y., Ohtake T., Brandt C. et al. Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Engl J Med 2002; 347: 1151-1160.
- Gallo R.L., Murakami M., Ohtake T. et al. Biology and clinical relevance of naturally occurring antimicrobial peptides J Allergy Clin Immunol 2002; 110: 823-831.
- Niyonsaba F., Nagaoka I., Ogawa H. Human defensins and cathelicidins in the skin: beyond direct antimicrobial properties. Crit Rev Immunol 2006; 26: 545-576.
- Schroder J.M., Harder J. Antimicrobial skin peptides and proteins. Cell Mol Life Sci 2006; 63: 469-486.
- Niyonsaba F., Suzuki A., Ushio H. et al. The human antimicrobial peptide dermcidin activates normal human keratinocytes. British Journal of Dermatology 2009 Feb; 160(2): 243-9.
- Howell M.D., Novak N., Bieber T. et al. Interleukin-10 downregulates anti-microbial peptide expression in atopic dermatitis. J Invest Dermatol 2005; 125: 738-745.
- Niyonsaba F., Ushio H., Nakano N. et al. Antimicrobial peptides human b-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines. J Invest Dermatol 2007; 127: 594-604.
- Wood L.C., Elias P.M., Calhoun C. et al. Barrier disruption stimulates interleukin-1 alpha expression and release from a preformed pool in murine epidermis. J Invest Dermatol 1996; 106: 397-403.
- Caubet C., Jonca N., Bratssand M. et al. Degradation of corneodesmosome protein by two serine protease of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7. J Invest Dermatol 2004; 122: 1235-1244.
- Ekholm I.E., Bratssand M., Egelrud T. Stratum corneum tryptic enzyme in normal epidermis: a missing link in the desquamation process? J Invest Dermatol 2000; 114: 56-63.
- Suzuki Y., Nomura J., Koyama J. et al. The role of proteases in stratum corneum: involvement in stratum corneum desquamation. Arch Dermatol Res 1994; 286: 369-375.
- Taieb A., Hanifin J., Cooper K. et al. Proceedings of the 4th Georg Rajka International Symposium on Atopic Dermatitis, Arcachon, France, September 15-17, 2005. J Allergy Clin Immunol 2006: 117: 378-390.
- Taieb A. Hypothesis: from epidermal barrier dysfunction to atopic disorders. Contact Dermatitis 1999; 41: 177-180.
- Chamlin S.L., Kao J., Freiden I.J. et al. Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity. J Am Acad Dermatol 2002; 47: 198-208.
- Cork M.J., Robinson D.A., Vasilopoulos Y. et al. New perspectives on epidermal barrier dysfunction in atopic dermatitis: gene-environment interactions. J Allergy Clin Immunol 2006; 118: 3-21.
- Ring J., Przybilla B., Ruzicka T., eds. Handbook of Atopic Eczema, 2nd edn., Springer, Heidelberg, 2006.
- Kawashima M., Hayashi N., Nogita T. et al. The usefulness of moisturizers for maintenance of remission in atopic dermatitis. Jpn J Dermatol 2007; 117: 1139-1145.
- Furue M., Furukawa F., Hide M. et al. Guidelines for therapy for atopic dermatitis 2004. Jpn J Dermatol 2004; 114: 135-142.
- Rawlings A.V., Harding C.R. Moisturization and skin barrier function Dermatol. Ther 2004; 17 (Suppl 1): 43-48.
- Levi K., Kwan A., Rhines A.S. et al. Emollient molecule effects on the drying stresses in human stratum corneum. British Association of Dermatologists 2010; 163: 695-703.
- Long C., Mills C., Finlay A. A practical guide to topical therapy in children Br J Dermatol 1998; 138: 293-296.
- Chamlin S.L., Kao J., Freiden I.J. et al. Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity. J Am Acad Dermatol 2002; 47: 198-208.