Photodynamic therapy with methyl aminolevulinate in the treatment of basal cell carcinoma

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Abstract

The article presents the results of the studies on the effectiveness of treatment basal cell carcinoma of the skin with photodynamic therapy with 5-aminolevulinic acid and methyl aminolevulinate. The results of the comparing trials between photodynamic therapy with methyl aminolevulinate and different other treatment modalities are presented.

About the authors

A. A. Kubanov

State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian Federation

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

I. N. Kondrakhina

State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian Federation

Email: noemail@neicon.ru
Russian Federation

N. V. Gribanov

State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian Federation

Email: gribanov@cnikvi.ru
Russian Federation

References

  1. Filonenko E.V. Fizicheskie metody v lechenii bol'nyh rakom kozhi. Medicinskie tehnologii. Ocenka i vybor 2012; 2: 100-105.
  2. Vejshner Ju.L. Statisticheskie dannye po Rossii po onkologicheskim zabolevanijam sredi naselenija 2010.
  3. Molochkov V.A., Mardi Sh. Novye podhody k lecheniju nemelanoticheskogo raka kozhi 2007; Al'manah klinicheskoj mediciny 2007; 15: 235-237.
  4. Kulagin V.I., Ponomarev B.A., Selisskij G.D. s soavt. Aktual'nye problemy sovershenstvovanija specializirovannoj pomoshhi bol'nym dermatozami. Ross zhurn kozhn venerich zabolevanij 2001; 6: 57-59.
  5. Shental' V.V., Malaev S.G., Pustynskij I.N. Rak kozhi. Medicinskaja pomoshh' 2000; 46: 10.
  6. Galil-Ogly G.A., Molochkov V.A., Sergeev Ju.V., Dermatoonkologija. M: Medicina dlja vseh 2005; 872.
  7. Indilova I. Lazernaja konfokal'naja mikroskopija v diagnostike i ocenke jeffektivnosti metodov lechenija bazal'no-kletochnogo raka kozhi. Jeksperi klini dermatokosmetol 2011; 4: 54-63.
  8. McCusker M., Basset-Seguin N., Dummer R. et al. Metastatic basal cell carcinoma: prognosis dependent on anatomic site and spread of disease. Eur J Cancer 2014; 50 (4): 774-783.
  9. Danial C., Lingala B., Balise R., Oro A.E. et al. Br J Dermatol. Markedly improved overall survival in 10 consecutive patients with metastatic basal cell carcinoma 2013; 169 (3): 673-676.
  10. V.N. Volgin, T.V. Sokolova, M.S. Kolbina, A.A. Sokolovskaya. Basalioma: Epidemiology, etiology, pathogenesis and clinical picture (part 1).
  11. V.N. Volgin, T.V. Sokolova, M.S. Kolbina, A.A. Sokolovskaya. Basalioma (part 2).
  12. B.A. Berenbejn, A.A. Studnicin. Differencial'naja diagnostika kozhnyh boleznej. 2-e izd. M: Medicina 1989.
  13. Cigna E., Tarallo M., Maruccia M. et al. Basal cell carcinoma: 10 years of experience. J Skin Cancer 2011;2011:476362.
  14. Roozeboom M.H., Arits A.H., Nelemans P.J., Kelleners-Smeets N.W. Overall treatment success after treatment of primary superficial basal cell carcinoma: a systematic review and meta-analysis of randomized and nonrandomized trials. Br J Dermatol. 2012; 167 (4): 733-756.
  15. Clark C.M., Furniss M., Mackay-Wiggan J.M. Basal cell carcinoma: an evidence-based treatment update. Am J Clin Dermatol 2014; 15 (3): 197-216.
  16. Bahner J.D., Bordeaux J.S. Non-melanoma skin cancers: photodynamic therapy, cryotherapy, 5-fluorouracil, imiquimod, diclofenac, or what? Facts and controversies. Clin Dermatol 2013; 31 (6): 792-798.
  17. Bath-Hextall F.J., Perkins W., Bong J., Williams H.C. Interventions for basal cell carcinoma of the skin. Cochrane Database Syst Rev. 2007; 24.
  18. Dieu T., Macleod A.M. Incomplete excision of basal cell carcinomas: a retrospective audit. ANZ J Surg. 2002; 72 (3): 219-221.
  19. Nagore E., Grau C., Molinero J., Fortea J.M. Positive margins in basal cell carcinoma: relationship to clinical features and recurrence risk. A retrospective study of 248 patients. J Eur Acad Dermatol Venereol. 2003; 17 (2): 167-170.
  20. Sokolova T.V, Volgin V.N. Jekonomicheskaja i klinicheskaja ocenka jeffektivnosti fotodinamicheskoj terapii bazal'no-kletochnogo raka kozhi. Ros zhurn kozhn venerich bol 2009; 2: 15-18.
  21. Ceilley R.I., Del Rosso J.Q. Current modalities and new advances in the treatment of basal cell carcinoma. Int J Dermatol. 2006; 45 (5): 489-498.
  22. Mosterd K., Krekels G.A., Nieman F.H. et al. Surgical excision versus Mohs' micrographic surgery for primary and recurrent basal-cell carcinoma of the face: a prospective randomised controlled trial with 5-years' follow-up. Lancet Oncol 2008; 9 (12): 1149-1156.
  23. Marghoob A., Kopf A.W., Bart R.S. et al. Risk of another basal cell carcinoma developing after treatment of a basal cell carcinoma. J Am Acad Dermatol. 1993; 28 (1): 22-28.
  24. Chissov V.I. Algoritmy objomov diagnostiki i lechenija zlokachestvennyh novoobrazovanij: metodicheskie ukazanija. M, 2002.
  25. Kolbina M.S., Sokolova T.V., Volgin V.N. Metod mestnogo obezbolivanija pri fotodinamicheskoj terapii bazal'nokletochnogo raka kozhi s applikacionnym naneseniem fotosensibilizatora. Klini dermatol venerol 2012; 4: 90-93.
  26. Pisklakova T.P., Il’in I.I. K voprosu ob effektivnosti lechenija bazaliomy kozhi. Vestn dermatol 1990; 6: 66-67.
  27. Ceilley R.I., Del Rosso J.Q. Current modalities and new advances in the treatment of basal cell carcinoma. Int J Dermatol 2006; 45 (5): 489-498.
  28. Silverman M.K., Kopf A.W., Gladstein A.H., et al. Recurrence rates of treated basal cell carcinomas. Part 4: X-ray therapy. J Dermatol Surg Oncol 1992; 18 (7): 549-554.
  29. Kunte C., Konz B. Current recommendations in the treatment of basal cell carcinoma and squamous cell carcinoma of the skin. Hautarzt 2007; 58 (5): 419-426.
  30. Martin H., Strong E., Spiro R.H. Radiation-induced skin cancer of the head and neck. Cancer. 1970; 25 (1): 61-71.
  31. Shajn A.A. Onkologija. М: Akademija, 2004. 544.
  32. Petit J.Y., Avril M.F., Margulis A. et al. Evaluation of cosmetic results of a randomized trial comparing surgery and radiotherapy in the treatment of basal cell carcinoma of the face. Plast Reconstr Surg 2000; 105 (7): 2544-2551.
  33. Kolbina M.S. Jeffektivnost' fotodinamicheskoj terapii bazal'no-kletochnogo raka kozhi s naneseniem applikacionnoj formy fotoditazina i ocenka otdalennyh rezul'tatov lechenija. Ros nauchn zhurn 2010; 6: 25-28.
  34. Pottier R., Krammer B., Baumgartner R. Photodynamic Therapy with ALA: A Clinical Handbook 2006. 13; 276.
  35. Thissen M.R., Neumann M.H., Schouten L.J. A systematic review of treatment modalities for primary basal cell carcinomas. Arch Dermatol 1999; 135 (10): 1177-1183.
  36. Thissen M.R., Nieman F.H., Ideler A.H. et al. Cosmetic results of cryosurgery versus surgical excision for primary uncomplicated basal cell carcinomas of the head and neck. Dermatol Surg 2000; 26 (8): 759-764.
  37. Jaroslavceva-Isaeva E.V., Kaplan M.A., Romanko Ju.S., Sokol N.I. Razrabotka metodiki fotodinamicheskoj terapii jeksperimental'noj opuholi (sarkoma M-1) pri lokal'nom vvedenii fotosensibilizatora. Ros bioterapevtich zhurn 2003; 2 (4): 19-22.
  38. Gelfond M.L. Fotodinamicheskaja terapija v onkologii. Praktich onkol 2007; 8 (4): 204- 210.
  39. Suhova T.E., Molochkov V.A., Romanko Ju.S., Changljan K.A., Tret'jakova E.I. Fotodinamicheskaja terapija aktinicheskogo keratoza s applikacionnym primeneniem Fotoditazina. Ros zhurn kozhn vener bol 2010; 5: 4-8.
  40. Suhova T.E., Molochkov V.A., Romanko Ju.S., s soavt. Lechenie bazal'nokletochnogo raka kozhi na sovremennom jetape. Al'manah klinicheskoj mediciny 2008; 18: 13-24
  41. Cyb A.F., Kaplan M.A., Romanko Ju.S., Popuchiev V.V. Fotodinamicheskaja terapija. Moskva: OOO Medicinskoe informacionnoe agentstvo; 2009.
  42. Boyle R.W., Dolphin D. Structure and biodistribution relationships of photodynamic sensitizers. Photochem Photobiol 1996; 64 (3): 469-485.
  43. Calzavara-Pinton P.G., Venturini M., Sala R. Photodynamic therapy: update 2006. Part 1: Photochemistry and photobiology. J Eur Acad Dermatol Venereol. 2007; 21 (3): 293-302.
  44. Gold M.H., Goldman M.P. 5-aminolevulinic acid photodynamic therapy: where we have been and where we are going. Dermatol Surg. 2004; 30 (8): 1077-1083.
  45. Kennedy J.C., Pottier R.H., Pross D.C. Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience. J Photochem Photobiol B 1990; 6 (1-2): 143-148.
  46. Fritsch C., Homey B., Stahl W. et al. Preferential relative porphyrin enrichment in solar keratoses upon topical application of delta-aminolevulinic acid methylester. Photochem Photobiol. 1998; 68 (2): 218-221.
  47. Ackermann G., Abels C., Baumler W. et al. Simulations on the selectivity of 5-aminolaevulinic acid-induced fluorescence in vivo. J Photochem Photobiol B. 1998; 47 (2-3): 121-128.
  48. Szeimes R.M., Karrer S., Abels C. et al. Photochemotherapy of cutaneous AIDS-associated Kaposi sarcoma with indocyanine green and laser light. Hautarzt 2001; 52 (4): 322-236.
  49. Boehncke W.H., Konig K., Ruck A., et al. In vitro and in vivo effects of photodynamic therapy in cutaneous T cell lymphoma. Acta Derm Venereol. 1994; 74 (3): 201-205.
  50. Morton C.A., Brown S.B., Collins S., et al. Guidelines for topical photodynamic therapy: report of a workshop of the British Photodermatology Group. Br J Dermatol 2002; 146 (4): 552-567.
  51. Kennedy J.C., Pottier R.H., Pross D.C. Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience. J Photochem Photobiol B. 1990; 6 (1-2): 143-148.
  52. Morton C.A., Whitehurst C., Moore J.V. Photodynamic therapy for large or multiple patches of Bowen disease and basal cell carcinoma. Arch Dermatol. 2001 Mar; 137 (3): 319-324.
  53. Clark C., Bryden A., Dawe R. et al. Topical 5-aminolaevulinic acid photodynamic therapy for cutaneous lesions: outcome and comparison of light sources. Photodermatol Photoimmunol Photomed 2003; 19 (3): 134-141.
  54. Wang I., Bendsoe N., Klinteberg C.A. et al. Photodynamic therapy vs. cryosurgery of basal cell carcinomas: results of a phase III clinical trial. Br J Dermatol 2001; 144 (4): 832-840.
  55. Peng Q., Warloe T., Berk K. et al. 5-Aminolevulinic acid-based photodynamic therapy. Clinical research and future challenges. 1997. Cancer 1997; 79 (12): 2282-2308.
  56. Morton C.A., Whitehurst C., Moore J.V. et al. Comparison of red and green light in the treatment of Bowen's disease by photodynamic therapy. Br J Dermatol 2000; 143 (4): 767-772.
  57. Fotinos N., Campo M.A., Popowycz F. et al. 5-Aminolevulinic acid derivatives in photomedicine: Characteristics, application and perspectives. Photochem Photobiol 2006; 82 (4): 994-1015.
  58. Moan J., Ma L.W., Iani V. On the pharmacokinetics of topically applied 5-aminolevulinic acid and two of its esters. Int J Cancer 2001; 92 (1): 139-143.
  59. Casas A., Fukuda H., Di Venosa G., Batlle A. Photosensitization and mechanism of cytotoxicity induced by the use of ALA derivatives in photodynamic therapy. Br J Cancer 2001; 85 (2): 279-284.
  60. Gaullier J.M., Berg K., Peng Q. et al. Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture. Cancer Res 1997; 57 (8): 1481-1486.
  61. Fritsch C., Homey B., Stahl W., et al. Preferential relative porphyrin enrichment in solar keratoses upon topical application of delta-aminolevulinic acid methylester. Photochem Photobiol 1998; 68 (2): 218-221.
  62. Juzenas P., Sharfaei S., Moan J., Bissonnette R. Protoporphyrin IX fluorescence kinetics in UV-induced tumours and normal skin of hairless mice after topical application of 5-aminolevu-linic acid methyl ester. J Photochem Photobiol B 2002; 67 (1): 11-17.
  63. Moan J., Ma L.W., Juzeniene A. et al. Pharmacology of protoporphyrin IX in nude mice after application of ALA and ALA esters. Int J Cancer 2003; 103 (1): 132-135.
  64. Basset-Seguin N., Bachmann I., Pavel S. et al. A dosefinding study of photodynamic therapy (PDT) with Metvix® in patients with basal cell carcinoma (BCC). 2000; European Academy of Dermatology and venerology. 1, 39.
  65. Soler A.M., Warloe T., Berner A., Giercksky K.E. A follow-up study of recurrence and cosmesis in completely responding superficial and nodular basal cell carcinomas treated with methyl 5-aminolaevulinate-based photodynamic therapy alone and with prior curettage. Br J Dermatol. 2001; 145 (3): 467-471.
  66. Horn M., Wolf P., Wulf H.C. et al. Topical methyl aminolaevulinate photodynamic therapy in patients with basal cell carcinoma prone to complications and poor cosmetic outcome with conventional treatment. Br J Dermatol 2003; 149: 1242-1249.
  67. Ramirez D.P., Kurachi C., Inada N.M. et al. Experience and BCC subtypes as determinants of MAL-PDT response: Preliminary results of a national Brazilian project. Photodiagnosis Photodyn Ther 2013; 10 (4): 703-709.
  68. Rhodes L.E., De Rie M., Enstrom Y. et al. Photodynamic therapy using topical methyl aminolevulinate vs surgery for nodular basal cell carcinoma: results of a multicenter randomized prospective trial. Arch Dermatol 2004; 140 (1): 17-23.
  69. Basset-Séguin N., Ibbotson S., Emtestam L. et al. Photodynamic therapy using methyl amino-laevulinate is as efficacious as cryotherapy in basal cell carcinoma, with better cosmetic results. Br J Dermatol 2003; 149: 46.
  70. Fantini F., Greco A., Del Giovane C. et al. Photodynamic therapy for basal cell carcinoma: clinical and pathological determinants of response. J Eur Acad Dermatol Venereol 2011; 25 (8): 896-901.
  71. Braathen L., Paredes B., Frolich K. et al. A dose finding study of photodynamic therapy (PDT) with Metvix in actinic keratosis (AK). J Eur Acad Dermatol 2000; 14: 38.
  72. Pariser D.M., Lowe N.J., Stewart D.M. Photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: results of a prospective randomized multicenter trial. J Am Acad Dermatol 2008; 59 (4): 569-576.
  73. Foley P., Freeman M., Siller G. et al. Photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: results of a prospective randomized multicenter trial. J Am Acad Dermatol 2003; 48 (2): 227-232.
  74. Tope W.D., Menter A., El-Azhary R.A. et al. Comparison of topical methylaminolevulinate photodynamic therapy versus placebo photodynamic therapy in nodular basal cell carcinoma. J Am Acad Dermatol 2004; 50 (3): 123.
  75. Morton C.A., Szemies R.M., Braathen L.R. Update on topical photodynamic therapy for skin cancer. Vestn dermatol venerol 2014; 6: 26-34.
  76. Guideline Subcommittee "Basal Cell Carcinoma" of the European Dermatology Forum. Update of the Guideline on Basal Cell Carcinoma. http://www.euroderm.org/images/stories/ guidelines/guideline_Basal_Cell_Carcinoma-update2012%20.pdf

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