Management of patients with congenital epidermolysis bullosa

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Abstract


Congenital epidermolysis bullosa (EB) is a clinically and genetically heterogeneous group of hereditary skin diseases characterized by the formation of blisters and/or erosions in response to minimal trauma. Etiopathogenetic methods for treating the disease are undergoing various stages of clinical research; therefore, external therapy implying caring for affected and non-affected skin remains to be the main treatment method. Such a therapy aims to reduce the healing period of erosive and ulcerative skin defects, thus improving the overall quality of patients’ life. This review sets out to provide clinical recommendations for the management of EB patients developed by different groups of experts, which generalize methods for treating EB patients, main principles of external therapy and relieving subjective sensations, as well as to describe specific situations entailing this pathology.

About the authors

A. E. Karamova

State Research Center of Dermatovenereology and Cosmetology, Ministry of Health of the Russian Federation

Email: fake@neicon.ru

Russian Federation

Cand. Sci. (Med.), Head of the Dermatology Department, 

Korolenko str., 3, bldg 6, Moscow, 107076

V. I. Albanova

State Research Center of Dermatovenereology and Cosmetology, Ministry of Health of the Russian Federation

Author for correspondence.
Email: albanova@rambler.ru

Russian Federation

Dr. Sci. (Med.), Assoc. Prof., Leading Researcher, Dermatology Department,

Korolenko str., 3, bldg 6, Moscow, 107076

E. S. Monchakovskaya

State Research Center of Dermatovenereology and Cosmetology, Ministry of Health of the Russian Federation

Email: fake@neicon.ru

Russian Federation

Junior Researcher, Dermatology Department, 

Korolenko str., 3, bldg 6, Moscow, 107076

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