Administration of levocetirizine (glencet) in eczema patients.Clinical and ultrasonic assessment of the efficacy


There was a clinical and ultrasonic study of the clinical efficacy of levocetirizine as a part of a complex therapy in 60
patients with eczema. The dynamic calculation of the EASI, EQ-5D and DLQI indices as well as analysis of ultrasound
showings made it possible to confirm the benefits of glencet vs. cetirizine for achieving the clinical effect. The eczema
therapy with glencet contributes to the elimination of both exudative and proliferative parts of the complex pathologic
chain of the disease in patients with this type of dermatosis.


  1. Rathod R.T., Misra D. FDC of montelukast with levocetirizine: focus on bilayer technology. J Indian med Assoc-2009; Aug; 107 (8): 562-4.
  2. Wu P., Mitchell S., Walsh G.M. A new antihistamine levocetirizine inhibits eosinophil adhesion to vascular cell adhesion molecule-1 under flow conditions. Clin exp Allergy 2005; Aug; 35 (8): 1073-9.
  3. Hansen J., Klimek L., Hörmann K. Pharmacological management of allergic rhinitis in the elderly: safety issues with oral antihistamines. Drugs Aging 2005; 22 (4): 289-96.
  4. Giustizieri M.L., Albanesi C., Fluhr J. et al. H1 histamine receptor mediates inflammatory responses in human keratinocytes. J Allergy clin Immunol 2004 Nov; 114 (5): 1176-82.
  5. Hasala H., Janka-Junttila M., Moilanen E. et al. Levocetirizine and cytokine production and apoptosis of human eosinophils. Allergy Asthma Proc 2007; Sep-Oct; 28 (5): 582-91.
  6. Гущин И.С. Разнообразие противоаллерги- ческого действия цетиризина. РАЖ 2006; 4: 33-44.
  7. Singh-Franco D., Ghin H.L., Robles G.I. et al. Levocetirizine for the treatment of allergic rhinitis and chronic idiopathic urticaria in adults and children. Clin Ther 2009; Aug; 31 (8): 1664-87.
  8. Walsh G.M. A review of the role of levocetirizine as an effective therapy for allergic disease. Expert Opin Pharmacother 2008 Apr; 9 (5): 859-67.
  9. Dubuske L.M. Levocetirizine: The latest treatment option for allergic rhinitis and chronic idiopathic urticarial. Allergy Asthma Proc 2007 Nov-Dec; 28 (6): 724-34.
  10. Simons F.E. H1-antihistamine treatment in young atopic children: effect on urticaria. Early Prevention of Asthma in Atopic Children Study Group. Ann Allergy Asthma Immunol 2007; Sep; 99 (3): 261-6. Литература
  11. Dhanya N.B., Rai R., Srinivas C.R. Histamine 2 blocker potentiates the effects of histamine 1 blocker in suppressing histamine-induced wheal. Indian J Dermatol Venereol Leprol 2008; Sep-Oct; 74 (5): 475-7.
  12. Hair P.I., Scott L.J. Levocetirizine: a review of its use in the management of allergic rhinitis and skin allergies. Drugs 2006; 66 (7): 973-96.
  13. Gillard M., Benedetti M.S., Chatelain P. et al. Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines. Inflamm Res 2005 Sep; 54 (9): 367-9.
  14. Camelo-Nunes I.C. New antihistamines: a critical view. J Pediat (Rio J) 2006; Nov; 82 (5 Suppl): S173-80.
  15. Petecchia L., Serpero L. The histamine-induced enhanced expression of vascular cell adhesion molecule-1 by nasal polyp-derived fibroblasts is inhibited by levocetirizine. Amer J Rhinol 2006; Sep-Oct; 20 (5): 445-9.
  16. Walsh G.M. Levocetirizine: an update. Curr Med Chem 2006; 13 (22): 2711-5.

Copyright (c) 2011 Bakulev A.L., Kravchenya S.S., Murashkin N.N., Bakulev A.L., Kravchenya S.S., Murashkin N.N.

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