Mikrobnaya ekzema: novye vozmozhnostikombinirovannoy topicheskoy terapii



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Abstract

The authors assessed clinical efficacy and safety of Supirocin-B for patients suffering from microbial eczema.
The dynamic assessment of EASI, Dermatological Index of Symptom Scale, DLQI and results of bacterioscopic
examination showed that evident positive results of the use of Supirocin-B in patients suffering from microbial eczema are
related to the strong antibacterial action of such a topical antibiotic as Mupirocin as well as high topical anti-inflammatory
action of betamethasone dipropionate.

References

  1. Charles J., Pan Y., Miller G. Aust Fam Physician. Eczema. 2011 Jul: 40 (7): 467.
  2. Кубанова А.А. (ред.) Дерматовенерология (Клинические рекомендации. Российское общество дерматовенерологов). М: ДЭКС-Пресс 2010; 428.
  3. Molin S., Vollmer S., Weiss E.H. et al. Deletion of the late cornified envelope genes LCE3B and LCE3C may promote chronic hand eczema with allergic contact dermatitis. J Investig Allergol Clin Immunol 2011; 21 (6): 472-9.
  4. Brown S.J., McLean W.H. Eczema genetics: current state of knowledge and future goals. J Invest Dermatol 2009 Mar; 129 (3): 543-52.
  5. Treadwell P.A. Eczema and infection. Pediatr Infect Dis J 2008 Jun; 27 (6): 551-2.
  6. Sohn A., Frankel A., Patel R.V. et al. Eczema. Mt Sinai J Med 2011 Sep-Oct; 78 (5): 730-9.
  7. Shams K., Grindlay D.J., Williams H.C. What's new in atopic eczema? An analysis of systematic reviews published in 2009-2010. Clin Exp Dermatol 2011 (Aug); 36 (6): 573-7.
  8. Кубанова A.А., Васильева Л.Л., Алексеева Л.В., Дмитриева Н.Г. Состояние иммунной системы у больных экземой. Вестн. дерматол. и венерол. 1983; (8): 16-19.
  9. Кубанова А.А., Делекторский В.В. Ультраструктурная характеристика нейтрофильных лейкоцитов периферической крови и количественная оценка цитоплазматических гранул у больных экземой. Вестн. дерматол. 1986; 6: 8-11.
  10. Lin X.R. Discussion on integrative medical research of treatment of eczema. Zhongguo Zhong Xi Yi Jie He Za Zhi 2008 Aug; 28 (8): 678-80.
  11. Biagini Myers J.M., Khurana Hershey G.K. Eczema in early life: genetics, the skin barrier, and lessons learned from birth cohort studies. J Pediatr 2010 Nov; 157 (5): 704-14.
  12. Bartlett A. Adult eczema. Nurs Stand 2010 Jun 30 - Jul 6; 24 (43): 51.
  13. Hughes A.M., Crouch S., Lightfoot T. et al. Eczema, birth order, and infection. Am J Epidemiol 2008 May 15; 167 (10): 1182-7.
  14. Galli E., Ciucci A., Cersosimo S. et al. Eczema and food allergy in an Italian pediatric cohort: no association with TLR-2 and TLR-4 polymorphisms. Int J Immunopathol Pharmacol 2010 Apr - Jun; 23 (2): 671-5.
  15. McPherson T., Sherman V.J., Aslam A. et al. Filaggrin null mutations associate with increased frequencies of allergen-specific CD4+ T-helper 2 cells in patients with atopic eczema. Br J Dermatol 2010 Sep; 163 (3): 544-9.
  16. Werfel T. Classification, trigger factors and course of chronic hand eczema. MMW Fortschr Med 2009 May 7; 151 (19): 31-4.
  17. Tanaka T., Satoh T., Yokozeki H. Dental infection associated with nummular eczema as an overlooked focal infection. J Dermatol 2009 Aug; 36 (8): 462-5.
  18. Lawton S. Assessing and treating adult patients with eczema. Nurs Stand. 2009 Jul 1-7; 23 (43): 49-56.
  19. Lundell A.C., Hesselmar B., Nordström I. et al. High circulating immunoglobulin A levels in infants are associated with intestinal toxigenic Staphylococcus aureus and a lower frequency of eczema. Clin Exp Allergy 2009 May; 39 (5): 662-70.
  20. Haslund P., Bangsgaard N., Jarløv J.O. et al. Staphylococcus aureus and hand eczema severity. Br J Dermatol 2009 Oct; 161 (4): 772-7.
  21. Stollery N. Eczema. Practitioner. 2009 Apr; 253 (1717): 33-5.
  22. Jayasekera A., Jennings L., Holden C.R. et al. Methicillin-resistant Staphylococcus aureus in skin disease affects mainly elderly patients with eczema and leg ulcers who have associated chronic disease. Acta Derm Venereol 2008; 88 (2): 156-8.
  23. Chang C., Keen C.L., Gershwin M.E. Treatment of eczema. Clin Rev Allergy Immunol 2007 Dec; 33 (3): 204-25.
  24. Богданович Т.М., Страчунский Л.С. Мупироцин: уникальный антибиотик для местного применения. Клин. микробиол. и антимикробн. химиотер. 1999; 1: 57-65.
  25. Глухенький Б.Т. Лечение пациентов с гнойничковыми заболеваниями кожи мазью «Бактробан» (Мупироцин). Укр. мед. часопис. 1999; 4 (12): VII-VIII.

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Copyright (c) 2011 Bakulev A.L., Kravchenya S.S., Murashkin N.N., Igonina I.A., Epifanova A.y., Slesarenko N.A.

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