Modern therapy of anogenital warts

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Abstract

Modern views on human papilloma virus are presented. Actual approaches to diagnostics and treatment of patients with anogenital warts are discussed. Clinical cases of high efficiency of Imiquimodum (Keravort) in treating anogenital warts of men and women are illustrated.

About the authors

A. A. Khryanin

Novosibirsk State Medical University

Author for correspondence.
Email: khryanin@mail.ru
Russian Federation

S. V. Klyuchareva

North-Western State Medical University named after I.I. Mechnikov

Email: noemail@neicon.ru
Russian Federation

O. A. Baftalovskaya

St. Petersburg GBUZ KVD № 7

Email: noemail@neicon.ru
Russian Federation

N. V. Lobzev

St. Petersburg GBUZ KVD № 7

Email: noemail@neicon.ru
Russian Federation

E. B. Pershchetskaya

St. Petersburg GBUZ KVD № 7

Email: noemail@neicon.ru
Russian Federation

References

  1. Human pathogenic papillomaviruses, topics in microbiology and immunology // Ed. H. zur Hausen. Berlin, 1994; 186: 131-157.
  2. Parkin D.M., Bray F. The burden of HPV-related cancers. Vaccine 2006; 24 (Suppl 3): 11-25.
  3. IARC WHU Press Release 151 IARC confirms efficacy of cervix cancer screening for women 25-65 in reducing mortality, 03 May 2004.
  4. Waggoner S. Cervical cancer. Lancet 2003; 361: 2217-2225. Литература
  5. Burchell A.N., Winer R.L., Sanjose S., Franco E.L. Epidemiology and transmission dynamics of genital HPV infection. Vaccine 2006; 24, S3: 52-61.
  6. Gravitt P.E., Jamshidi R. Diagnosis and management of oncogenic cervical human papillomavirus infection. Infect Dis Clin North Am 2005; 19: 439-458.
  7. McIntosh N. Human papillomavirus and cervical cancer. JHPIEGO Strategy Paper № 8, May 2000.
  8. Partridge J.M., Koutsky LA. Genital human papillomavirus infection in men. Lancet Infectious Diseases 2006; 6: 21-31.
  9. Protokoly vedeniya bol'nykh. Infektsii, peredavaemye polovym putem. M: N'yudiamed, 2011; 464. [Протоколы ведения больных. Инфекции, передаваемые половым путем. М: Нью-диамед 2011; 464.]142 к № 5, 2015
  10. Khryanin A.A., Reshetnikov O.V. Papillomavirusnaya infektsiya: sovremennyy vzglyad na epidemiologiyu, profilaktiku i lechenie. Ginekologiya 2013; 15 (5): 4-8. [Хрянин А.А., Решетников О.В. Папилломавирусная инфекция: современный взгляд на эпидемиологию, профилактику и лечение. Гинекология 2013; 15 (5): 4-8.]
  11. von Krogh G., Lacey C.J., Gross G. et al. European course on HPV associated pathology. Sex Transm Inf 2000; 76: 162-168.
  12. Ferenczy A. Epidemiology and clinical pathophysiology of condylomata acuminate. Am J Obstet Gynecol 1995; 172: 1331-1339.
  13. Koutsky L., Galloway D., Holmes K. Epidemiology of genital human papillomavirus infection. Epidemiol Rev 1988; 10: 122-163.
  14. Stone K.M. Human papillomavirus and genital warts: update on epidemiology and treatment. Clin Infect Dis 1995: 20; 91-97.
  15. Heaton C.L. Clinical manifestations and modern management of condylomata acuminate:a dermatologic perspective. Am J Obstet Gynecol 1995; 172: 1345-1350.
  16. Fleurence R.L., Dixon J.M., Milanova T.F., Beusterien K.M. Review of the economic and quality-of-life burden of cervical human papillomavirus disease. Am J Obstet Gynecol 2007; 196 (3): 206-212.
  17. Eron S.J., Judson F., Tucker S. et al. Inerferon therapy for condyloma acuminata. N Engl J Med 1986; 315: 1059-1064.
  18. Friedman-Kein A.E., Eron L.J., Conant M. et al. Natural interferon alfa for treatment of condyloma acuminate. JAMA. 1988; Vol. 259: 533-538.
  19. Tyring S.K., Arany I., Stanley M.A. A randomized, controlled, molecular study of condylomata acuminate clearance drug treatment with imiquimod. J Infect Dis 1998; 178: 551-555.
  20. Miller R.L., Gerster J.F., Owens M.A. et al. Imiquimod applied topically: a novel immune response modifier and new class of drag. Int J Immunopharmacol 1999; 21: 1-14.
  21. Megyeri K., Au W.-C., Rosztoczy I. et al. Stimulation of interferon and cytokine gene expression by imiquimod and stimulation by Sendai virus utilize similar signal transduction pathways. Mol Cell Biol 1995; 15: 2207-2218.
  22. Gibson S.J., Imbertson L.M., Wagner T.L. et al. Cellular requirements for cytokine induction in response to the immunomodulators imiquimod and S-27609. Interferon Cytokine Res 1995; 15: 537-545.
  23. Testerman T.L., Gerster J.F., Imbertson L.M. et al. Cytokine induction by the immunomodulators imiquimod and S-27609. J Leukoc Biol 1995; 58: 365-372.
  24. Stone K.M. Human papillomavirus and genital warts: update on epidemiology and treatment. Clin Infect Dis 1995; 20: 91-97.
  25. Heaton C.L. Clinical manifestations and modern management of condylomata acuminate:a dermatologic perspective. Am J Obstet Gynecol 1995; 172: 1345-1350.
  26. Bashi S.A. Cryotherapy versus podophyllin in the treatment genital warts. J Int Dermatol 1985; 24: 535-536.
  27. Godley M., Bradbeer C., Gellan M. Thin R.N. Cryotherapy compared with trichloroacetatic acid in treating genital warts. Genitourin Med 1987; 63: 390-392.
  28. O’Mahony C., Law C., Gollnick H.P. et al. Patients attitudes to genital wart therapies. Int J STD&AIDS 2001; 12: 567-570.
  29. Rakhmatulina M.R., Kubanov A.A., Samtsov A.V. et al. Clinical efficacy, safety and tolerance of the Kerawort (imiquimod) cream used for treatment of anogenital warts. Vestn Dermatol Venerol 2015; (1): 126-130. [Рахматулина М.Р., Кубанов А.А., Самцов А.В. и др. клиническая эффективность, безопасность и переносимость крема кераворт (имихимод) в терапии аногенитальных бородавок. Вестн дерматол венерол 2015; (1): 126-130.]
  30. Rakhmatulina M.R., Semenenko A.V. Comparison of methods for diagnostics and treatment of clinical manifestations of the papilloma viral infection. Vestn Dermatol Venerol 2015; (1): 46-53. [Рахматулина М.Р., Семененко А.В. Сравнительный анализ методов диагностики и терапии клинических проявлений папилломавирусной инфекции. Вестн дерматол венерол 2015; (1): 46-53.]
  31. European STD Guidelines. Int J STD AIDS 2001; 12 (Suppl.3): 722-729.
  32. CDC Recommendations and reports. 2002; 51: RR-6: 53-57.
  33. Klinicheskie rekomendatsii RODVK. Vedenie bol'nykh IPPP i urogenital'nymi infektsiyami. M: Delovoy ekspress 2013, 112. [клинические рекомендации РОДВк. Ведение больных ИППП и урогенитальными инфекциями. М: Деловой экспресс 2013; 112.]
  34. Katsambas A.D., Lotti T.M. Evropeyskoe rukovodstvo po lecheniyu dermatologicheskikh bolezney. M: MEDpress-inform, 2014. 84-86. [кацамбас А.Д., Лотти Т.М. Европейское руководство по лечению дерматологических болезней. М: МЕДпресс-информ 2014; 84-86.]

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Copyright (c) 2015 Khryanin A.A., Klyuchareva S.V., Baftalovskaya O.A., Lobzev N.V., Pershchetskaya E.B.

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