Nummular eczema in children and adults: clinical picture and differential therapy approaches

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The article deals with present-day ideas on pathogenesis and treatment of Nummular eczema, differences between clinical I picture of the disease with children and adults.

About the authors

D. B. Proshutinskaia

State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian Federation

Author for correspondence.
Russian Federation

P. A. Skripkina

The Russian National Research Medical University named after N.I. Pirogov (RNRMU)

Russian Federation


  1. Soter N.A. Nummular eczema and lichen simplex chronicus/prurigo nodularis. In: Freedberg I.M., Eisen A.Z., Wolff K., Austen K.F., Goldsmith L.A., Katz S.I., editors. fitzpatrick's Dermatology in general medicine. 6th ed. New York: Mc Graw-Hill; 2003; 1194-6
  2. Cowan M.A.: Nummular eczema: A review, followup and analysis of a series of 325 cases. Acta Derm Venereol 41: 453-460, 1961.
  3. Hellgren L., Mobacken H.: Nummular eczema-clinical and statistical data. Acta Derm Venereol 49: 189-196, 1969.
  4. Kulthanan K., Boochangkool K., Tuchinda P., Chularojanamontri L. Clinical features of the extrinsic and intrinsic types of adult-onset atopic dermatitis. Asia Pac Allergy 2011; 1: 80-6.
  5. Jiamton S.1, Tangjaturonrusamee C., Kulthanan K. Clinical features and aggravating factors in nummular eczema in Thais. Asian Pac J Allergy Immunol 2013 Mar; 31 (1): 36-42.
  6. Aoyama H. et al: Nummular eczema: An addition of senile xerosis and unique cutaneous reactivities to environmental aeroallergens. Dermatology 199: 135-139, 1999.
  7. fleming C., Parry E., forsyth A., Kemmett D. Patch testing in discoid eczema. Contact Dermatitis 1997; 36: 261-4.
  8. Adachi A., Horikawa T., Takashima T., Ichihashi M. Mercuryinduced nummular dermatitis. J Am Acad Dermatol 2000; 43: 383-5.
  9. Bettoli V., Tosti A., Varotti C. Nummular eczema during isotretinoin treatment. J Am Acad Dermatol 1987; 16: 617.
  10. Tanaka T., Satoh T., Yokozeki H. Dental infection associated with nummular eczema as an overlooked focal infection. J Dermatol 2009; 36: 462-465.
  11. Krol A., Krafchik B. The differential diagnosis of atopic dermatitis in childhood. Dermatol Ther 19: 73-82, 2006.
  12. Carr R.D., Berke M., Becker S.W. Incidence of Atopy in the General Population. Arch Dermatol. 1964; 89: 27-32.
  13. Suh L., Coffin S., Leckerman K.H. et al. Methicillin-resistant Staphylococcus aureus colonization in children with atopic dermatitis. Pediatr Dermatol 2008; 25 (5): 528-34.
  14. Tang C.S., Wang C.C., Huang C.F. et al. Antimicrobial susceptibility of Staphylococcus aureus in children with atopic dermatitis. Pediatr Int 2011; 53 (3): 363-7.
  15. Balma-Mena A., Lara-Corrales I., Zeller J. et al. Colonization with communityacquired methicillin-resistant Staphylococcus aureus in children with atopic dermatitis: a cross-sectional study. Int J Dermatol 2011; 50 (6): 682-8.
  16. Hoeger PH, Ganschow R, finger G. Staphylococcal septicemia in children with atopic dermatitis. Pediatr Dermatol 2000; 17 (2): 111-4.
  17. Nakamura M.M., Rohling K.L., Shashaty M. et al. Prevalence of methicillin-resistant Staphylococcus aureus nasal carriage in the community pediatric population. Pediatr Infect Dis J 2002; 21 (10): 917-22.
  18. Sandilands A., Terron-Kwiatkowski A., Hull P.R. et al. Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema. Nat Genet 2007; 39: 650-4.
  19. Nomura I., Goleva E., Hovell M. et all. Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes. J Immunol 2003; Vol. 15: 3262-3269.
  20. Breuer K., Kapp A., Werfel T. Bacterial infections and atopic dermatitis. Allergy 2001; 56 (11): 1034-41.

Copyright (c) 2015 Proshutinskaia D.B., Skripkina P.A.

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