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PH OF THE TOPICAL DRUG VEHICLE: SELECTING AN OPTIMUM VALUE AND ROLE OF THE BUFFER SYSTEM
- Authors: Dukhanin A.S.1
-
Affiliations:
- Pirogov Russian National Research Medical University
- Issue: Vol 92, No 2 (2016)
- Pages: 110-114
- Section: DRUG TREATMENT IN DERMATOVENEROLOGY
- Submitted: 24.08.2017
- Published: 24.04.2016
- URL: https://vestnikdv.ru/jour/article/view/233
- DOI: https://doi.org/10.25208/0042-4609-2016-92-2-110-114
- ID: 233
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Abstract
The following three groups of factors must be taken into consideration for selecting an optimum pH value of a topical drug: pharmaceutical, pharmacological and compatibility factors. To ensure a stable pH value, the drug vehicle comprises different buffer systems: single component and two-component ones. The optimum conditions for selecting and maintaining the vehicle pH were examined by the example of glucocorticosteroid-based topical drugs.
About the authors
A. S. Dukhanin
Pirogov Russian National Research Medical University
Author for correspondence.
Email: das03@rambler.ru
Россия
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Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).