Onychomycosis: features external therapy

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Abstract


Onychomycosis - one of the most frequent diseases with defeat of a nail bed, matrics and nail plate of a fungal origin. Frequency of an onychomycosis in Russia reaches 5% (to 15 million people), and practically every tenth visit of the dermatologist is connected with this pathology. Treatment of an onychomycosis still remains very difficult task. Application of varnishes, ointments with antimycotics and local agents on an oil basis has an essential shortcoming - insufficient receipt of a preparation to the center of pathological changes. It is supposed that for optimum therapy it is necessary to influence: first, from frontal and distal part of a nail, secondly, to apply aqueous-alcoholic solutions of a preparation which can freely get into subnail spaces with the phenomena of an onycholysis. For example, it has been shown highly efficient application of naftifina a hydrochloride under control of solution of the diamond green, showing diffusion distribution active ingredient to subnail space and on channels.

About the authors

D. V. Zaslavsky

St. Petersburg State Pediatric Medical University

Author for correspondence.
Email: venerology@gmail.com

Russian Federation

I. N. Chuprov

State Medical University by the name I.I. Mechnikov

Email: venerology@gmail.com

Russian Federation

A. A. Sidikov

Leningrad Regional Center of specialized types of medical care

Email: venerology@gmail.com

Russian Federation

M. G. Khvedelidze

St. Petersburg State Pediatric Medical University

Email: venerology@gmail.com

Russian Federation

O. B. Tatarskaya

St. Petersburg State Pediatric Medical University

Email: venerology@gmail.com

Russian Federation

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