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Сlinical case of a blast plasmocytoid dendritic cell tumor
- Authors: Milikhina E.N.1, Chermnykh T.V.1, Koshkin S.V.2, Maximov O.D.3
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Affiliations:
- 4 Military Hospital of the National Guard of the Russian Federation
- Kirov State Medical University, Ministry of Health of the Russian Federation
- Kirov Research Institute of Hematology and Blood Transfusion, Federal Medical Biological Agency of the Russian Federation
- Issue: Vol 94, No 6 (2018)
- Pages: 52-59
- Section: CLINICAL CASE REPORTS
- Submitted: 17.04.2019
- Accepted: 17.04.2019
- Published: 17.12.2018
- URL: https://vestnikdv.ru/jour/article/view/456
- DOI: https://doi.org/10.25208/0042-4609-2018-94-6-52-59
- ID: 456
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Abstract
The reason for writing this article was the difficulty in the differential diagnosis of skin lesions in a patient of 40 years, with a preliminary diagnosis of T-cell lymphoma. During the examination, including histological, immunomorphological, immunohistochemical methods, markers of various cell lines (T, B, myeloid) were detected. This feature is characteristic of lymphomas from plasmacytoid dendritic cells (MAC), a new nosological unit. In the WHO classification (2001), tumors with a similar phenotype were included in the lymphoma section of natural killer cells (NK-blast lymphomas). The clinical case described by us illustrates the need for an integrated approach in the diagnosis of lymphomas, which makes it possible to promptly assign adequate therapy.
About the authors
E. N. Milikhina
4 Military Hospital of the National Guard of the Russian Federation
Email: fake@neicon.ru
Dermatovenerologist,
Luganskaya str., 57, Kirov, 610044
РоссияT. V. Chermnykh
4 Military Hospital of the National Guard of the Russian Federation
Email: fake@neicon.ru
Dermatovenerologist,
Luganskaya str., 57, Kirov, 610044
РоссияS. V. Koshkin
Kirov State Medical University, Ministry of Health of the Russian Federation
Author for correspondence.
Email: koshkin_sergei@mail.ru
Dr. Sci. (Med.), Prof., Head of Department, Department of Dermatovenereology and Cosmetology,
Karla Marksa str., 112, Kirov, 610027
РоссияO. D. Maximov
Kirov Research Institute of Hematology and Blood Transfusion, Federal Medical Biological Agency of the Russian Federation
Email: fake@neicon.ru
Hematologist,
Krasnoarmeyskaya str., 72, Kirov, 610027
РоссияReferences
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