Email this article 
Acne therapy in adolescent children
- Authors: Perlamutrov Y.N. 1, Olkhovskaia K.B. 1, Lyapon A.O. 1
- Affiliations:
- A. I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation
- Issue: Vol 94, No 6 (2018)
- Pages: 60-66
- Section: DRUG TREATMENT IN DERMATOVENEROLOGY
- URL: https://vestnikdv.ru/jour/article/view/457
- DOI: https://doi.org/10.25208/0042-4609-2018-94-6-60-66
Abstract
Current knowledge of the pathogenesis of acne determines the need for early use of drugs with antiinflammatory activity.
Aim: to determine the effectiveness of monotherapy using Adaklin cream in the treatment of acne in adolescent children.
Material and methods. All adolescents with acne of light and moderate severity were examined to determine the dermatological index of acne (DIA), determine the level of production of sebaceous glands, testing the parents of patients. Monotherapy was performed using Adaklin cream.
Results. 60 patients with acne were under observation. Formation of clinical remission was registered in 78.33 % of adolescents. A good tolerability of the therapy and a high level of compliance were noted.
Conclusion: the high efficacy and tolerability of therapy with the use of Adaklin cream in adolescents with acne was stated.
Keywords
About the authors
Yu. N. Perlamutrov
A. I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation
Email: fake@neicon.ru
Russian Federation
Dr. Sci. (Med.), Prof., Head of the Department of Skin,
Delegatskaya str., 20, bldg 1, Moscow, 127473
K. B. Olkhovskaia
A. I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation
Author for correspondence.
Email: olhovskaya_kira@mail.ru
Russian Federation
Cand. Sci. (Med.), Associate Professor of the Department of Skin and Venereal Diseases,
Delegatskaya str., 20, bldg 1, Moscow, 127473
A. O. Lyapon
A. I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation
Email: fake@neicon.ru
Russian Federation
Cand. Sci. (Med)., Assistant of the Department of Skin and Venereal Diseases,
Delegatskaya str., 20, bldg 1, Moscow, 127473
References
- Pawin H., Chivot M., Beylot C. et al. Living with acne. A study of adolescents personal experiences. Dermatology. 2007;215(4):308–314. doi: 10.1159/000107624
- James W. D. Clinical practice. Acne. N Engl J Med. 2005;352(14):1463–1472. doi: 10.1056/NEJMcp033487
- Thiboutot D. M. Overview of acne and its treatment. Cutis. 2008;81(Suppl. 1):3–7.
- Mallon E., Newton J. N., Klassen A., Stewart-Brown S. L., Ryan T. J., Finlay A.Y. The quality of life in acne: a comparison with general medical conditions using generic questionnaires. Br J Dermatol. 1999;140(4):672–676. doi: 10.1046/j.1365-2133.1999.02768.x
- Baldwin H. E. The interaction between acne vulgaris and the psyche. Cutis. 2002;70(2):133–139.
- Gupta M. A., Gupta A. K. Depression and suicidal ideation in dermatology patients with acne, alopecia areata, atopic dermatitis and psoriasis. Br J Dermatol. 1998;139(5):846–850. doi: 10.1046/j.1365- 2133.1998.02511.x
- Адаскевич В. П. Акне вульгарные и розовые. М.: Медицинская книга, 2005.
- Krowchuk D. P. Managing adolescent acne: a guide for pediatricians. Pediat Rev. 2005;26(7):250–261. doi: 10.1542/pir.26-7-250
- Jeremy A. H., Holland D. B., Roberts S. G., Thomson K. F., Cunliffe W. J. Inflammatory events are involved in acne lesion initiation. J Invest Dermatol. 2003;121(1):20–27. doi: 10.1046/j.1523-1747.2003.12321.x
- Do T. T., Zarkhin S., Orringer J. S. et al. Computer-assisted alignment and tracking of acne lesions indicate that most inflammatory lesions arise from comedones and de novo. J Am Acad Dermatol. 2008;58(4):603–608. doi: 10.1016/s0093-3619(09)79319-0
- Weiss J. S. Messages from molecules: deciphering the code. J Drugs Dermatol. 2013;12(6):70–72.
- Zouboulis C. C. Propionibacterium acnes and sebaceous lipogenesis: a love-hate relationship? J Invest Dermatol. 2009;129(9):2093– 2096. doi: 10.1038/jid.2009.190
- Shaheen B., Gonzalez M. A microbial aetiology of acne: what is the evidence? Br J Dermatol. 2011;65(3):474–485. doi: 10.1111/j.1365-2133.2011.10375.x
- Перламутров Ю. Н., Ольховская К. Б. Терапия больных с тяжелой и средней степенью тяжести акне. Вестник дерматологии и венерологии. 2015;(3):141–146.
- Yentzer B. A., Irby C. E., Fleischer A. B., Feldman S. R. Differences in acne treatment prescribing patterns of pediatricians and dermatologists: an analysis of nationally representative data. Pediatric dermatology. 2008;25(6):635–639. doi: 10.1111/j.1525-1470.2008.00790.x
- Игнатьев Д. В., Кочергин Н. Г. Дерматологические индексы в доказательной медицине. IX Всероссийский съезд дерматовенерологов. 2005;2:11–12.
- Аравийская Е. Р. Современный взгляд на лечение акне: состояние проблемы и новые возможности. Лечащий врач. 2003;(04/03):4–6.
- Nast A., Dreno B., Bettoli V. et al. European evidence-based (S3) guidelines for the treatment of acne. J Eur Acad Dermatol Venereol. 2012;26(Suppl. 1):20. doi: 10.3410/f.14260957.15768252