Treatment of seborrheic keratosis with a copper vapour laser

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Abstract

Aim: to assess the efficacy and side-effect risk of the surgical treatment of seborrheic k eratosis (SK) using a copper vapour laser (CVL).

Patients and methods. 3980 patients (1214 men and 2766 women aged 20 to 78 years) suffering from SK were treated using a CVL (Yakhroma-Med model, Russian producer) equipped with a laser pen and a scanning nozzle. The laser treatment was performed without anaesthesia in one to four sessions. During the treatment procedure, the following radiation parameters were applied: wavelengths ranging from 511 to 578 nm (in the ratio of 3 to 2), an average power of 0.6–1.2 W and an exposure duration ranging from 0.2 to 0.4 s. The diameter of the light spot on the skin surface was 1 mm. The follow-up observation lasted 24 months.

Results. The computer simulation of tissue heating by CVL and other laser systems showed that CVL is an optimal treatment choice for seborrheic keratosis in terms of the energy deposition depth. According to our clinical data and the results of computer simulation, the CVL is established to be the safest and the most effective for seborrheic keratosis treatment.

About the authors

S. V. Klyuchareva

North-Western State Medical University named after I. I. Mechnikov, Ministry of Health of the Russian Federation

Author for correspondence.
Email: genasveta@rambler.ru
Светлана Викторовна Ключарева* — д.м.н., профессор кафедры дерматовенерологии Россия

I. V. Ponomarev

Lebedev Physical Institute, Russian Academy of Sciences

Email: iponom@okb.lpi.troitsk.ru
Игорь Владимирович Пономарев — к.ф.-м.н., руководитель проекта Россия

S. B. Topchiy

Lebedev Physical Institute, Russian Academy of Sciences

Email: fake@neicon.ru
Сергей Борисович Топчий — к.ф.-м.н., научный сотрудник Россия

A. E. Pushkareva

Saint Petersburg National Research University of Information Technologies, Mechanics and Optics (ITMO University)

Email: alexandra.pushkareva@gmail.com
Александра Евгеньевна Пушкарева — к.т.н., тьютор, кафедра лазерных технологий и систем Россия

Yu. N. Andrusenko

Saint Petersburg National Research University of Information Technologies, Mechanics and Optics (ITMO University)

Email: fake@neicon.ru
Юрий Николаевич Андрусенко — дерматоонколог, лазерный хирург Россия

References

  1. Culbertson G. R. 532-nm diode laser treatment of seborrheic keratoses with color enhancement. Dermatologic Surgery. 2008;34(4):525–528.
  2. Mehrabi D., Brodell R. T. Use of the alexandrite laser for treatment of seborrheic keratosis. Dermatologic surgery. 2002;28(5):437–439.
  3. Sayan A. et al. Management of seborrhoeic keratosis and actinic keratosis with an erbium: YAG laser-experience with 547 patients. International journal of oral and maxillofacial surgery. 2019;48(7):902–907.
  4. Fitzpatrick R. E., Goldman M. P., Ruiz-Esparza J. Clinical advantage of the CO2 laser superpulsed mode: treatment of verruca vulgaris, seborrheic keratoses, lentigines, and actinic cheilitis. The Journal of dermatologic surgery and oncology. 1994;20(7):449–456.
  5. Alam M., Warycha M. Complications of lasers and light treatments. Dermatologic therapy. 2011;24(6):571–580.
  6. Alegre-Sanchez A., et al. Treatment of flat and elevated pigmented disorders with a 755-nm alexandrite picosecond laser: clinical and histological evaluation. Lasers in medical science. 2018;33(8):1827–1831.
  7. Rajgopal Bala H., Pan Y., Nixon R. L. The dangers of non-medical laser therapy for pigmented lesions. The Medical Journal of Australia. 2017;206(5):229.
  8. Anderson R.R., Parrish J. A. Microvasculature can be selectively damaged using dye lasers: a basic theory and experimental evidence in human skin. Lasers in Surgery and Medicine. 1981;(1)3:263; Cho S., Choi Y. J., Kang J. S. Treatment of epidermal pigmented lesions with 578 nm yellow laser. Medical Lasers; Engineering, Basic Research, and Clinical Application. 2015;4(1):35–38.
  9. Somyos K., Boonchu K., Somsak K., et al. Copper vapour laser treatment of café-au-lait macules. Br J Dermatol. 1996;135(6):964–968.
  10. Lee H. I., Lim Y. Y., Kim B. J. et al. Clinicopathologic efficacy of copper bromide plus yellow laser (578 nm with 511 nm) for treatment of melasma in Asian patients. Dermatol Surgery. 2010;36(6):885–893.
  11. Dinehart S. M., Waner M., Flock S. The copper vapor laser for treatment of cutaneous vascular and pigmented lesions. The Journal of dermatologic surgery and oncology. 1993;19(4):370–375.
  12. Pushkareva A. E. Ponomarev I. V., Isaev A. A. Pushkareva A. E., Klyuchareva S. V. Numerical investigation of vessel heating using a copper vapor laser and a pulsed dye laser in treating vascular skin lesions. Laser Physics. 2018;28(2):025604.
  13. Ponomarev I. V., Topchiy S. B., Pushkareva A. E., Klyuchareva S. V. Numerical simulation of port-wine stain blood vessel selective heating using a copper vapor laser with a scanner. Laser Physics. 2019;29(4):045601.
  14. Ключарева С. В., Пономарев И. В., Пушкарева А. Е. Лечение сосудистых мальформаций кожи с применением лазеров на парах меди и импульсного лазера на красителе. Вестник дерматологии и венерологии. 2018;94(1):67–77. [Klyuchareva S. V., Ponomarev I. V., Pushkareva A. E. Therapy of skin vascular malformations using copper vapor laser and pulsed dye laser. Vestnik dermatologii i venerologii. 2018;94(1):67–77. (In Russ.)]
  15. Desiate A. et al. 980 nm diode lasers in oral and facial practice: current state of the science and art. International Journal of Medical Sciences. 2009;6(6):358.
  16. Suh H., Han K. H., Chung J. H. The use of Q-switched Nd: YAG laser in the treatment of superficial pigmented lesions in Koreans. Journal of Dermatological Treatment. 2001;12(2):91–96.
  17. Sherwood K.A., Murray S., Kurban A.K., Tan O.T. Effect of wavelength on cutaneous pigment using pulsed irradiation. Effect of wavelength on cutaneous pigment using pulsed irradiation. J Invest Dermatol. 1989;92(5):717–720.
  18. Smithies D. J., Butler P. H., Pickering J. W., Walker E. P. A computer controlled scanner for the laser treatment of vascular lesions and hyperpigmentation. Clin Phys Physiol Meas. 1991;12(3):261–267.
  19. Clementoni M. T., Gilardino P., Muti G. F. Non-sequential fractional ultrapulsed CO2 resurfacing of photoaged facial skin: preliminaryclinical report. J Cosmet Laser Ther. 2007;9(4):218–225.
  20. Ключарева С. В., Пономарев И. В., Топчий С.Б. Пушкарева А. Е. Лечение ринофимы с помощью лазера на парах меди. Вестник дерматологии и венерологии. 2018;94(5):50–58. [Klyuchareva S. V., Ponomarev I. V., Topchiy S. B., Pushkareva A. E. Treatment of rhinophyma using a copper vapor laser. Vestnik dermatologii i venerologii. 2018;94(5):50–58. (In Russ.)]
  21. Ключарева С. В., Пономарев И. В., Топчий С. Б. и др. Лечение базальноклеточного рака кожи в периорбитальной области импульсным лазером на парах меди. Вестник дерматологии и венерологии. 2018;94(6):15–21. [Klyuchareva S. V., Ponomarev I. V., Topchiy S. B. et al. Treatment of basal cell cancer in the periorbital area using a pulsed copper vapour laser. Vestnik dermatologii i venerologii. 2018;94(6):15–21. (In Russ.)]

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Copyright (c) 2019 Klyuchareva S.V., Ponomarev I.V., Topchiy S.B., Pushkareva A.E., Andrusenko Y.N.

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