Vol 92, No 6 (2016)

Cover Page

ORIGINAL STUDIES

Nodular skin melanomas and dermatoscopic diagnostic therein

Zhuchkov M.V., Tarasova M.A., Sonin D.B.

Abstract

Aim. The study of dermatoscopic pattern characteristics of nodular melanoma with the use of modified Kittler’s pattern analysis. Materials and methods. Clinical and dermatoscopis images of 127 patients with histologically distinctive nodular form of skin melanoma were examined. Nonpolarized dermoscopy of nodular melanoma foci was carried out to patients. Interpretation of obtained dermatoscopic images was performed with the use of pattern analysis modified by Harold Kittler. Main results. The two most important dermatoscopic features of nodular melanoma that distinguish it from other clinical types of this malignant tumor were revealed in our investigation: 1) the prevalence of dermatoscopis images with one pattern (structureless); 2) the prevalence of “grey dots, circles, clods” and “black peripheral dots and clods” as main features of nodular melanoma.
Vestnik dermatologii i venerologii. 2016;92(6):27-33
pages 27-33 views

Clinical efficasy of L-arginine and ursodeoxycholic acid in the complex treatment of rosacea

Baltabaev M.K., Shakirova A.T., Baltabaev A.M.

Abstract

Under clinical observation were 77 patients suffered from different clinical forms of acne rosacea that using L-arginin and Ursodeoxycholic acid had treated All patients have functional and organic disturbances of hepatobiliary system before treatment. Complex treatment including L-arginin and Ursodeoxycholic acid led to improvement of balance of liver enzymes and lipid fractions in peripheric blood of investigated patients.
Vestnik dermatologii i venerologii. 2016;92(6):34-42
pages 34-42 views

CLINICAL CASE REPORTS

Actinic reticuloid. Diagnostics

Sokolovskiy E.V., Micheev G.N., Demidova E.I.

Abstract

This article is about the case of actinic reticuloid - the rare dermatosis which clinical presentation is similar to atopic dermatitis, T-cell lymphoma. Good treatment effect was obtained by long cycles (2 cycles for 3 months) of hydroxychloroquine and sun protective therapy included sunscreens SPF 50, nicotinic acid, sun-safe clothes which blocked ultraviolet radiation without any glucocorticosteroid drugs and cytostatic treatment.
Vestnik dermatologii i venerologii. 2016;92(6):57-60
pages 57-60 views

Squamous cell carcinoma of penis in patient with incipient neurosyphilis

Zaslavsky D.V., Egorova Y.S., Chuprov I.N., Fedorchenko A.B., Mareha G.L., Fomenko M.N., Gurkovskaya Y.Y., Parxomenko S.I., Timoshchuk E.A., Kozlova L.I., Sidikov A.A.

Abstract

Squamous cell carcinoma of the skin (SSCC) is one of the most common malignant skin tumors. Syphilis is a sexually transmitted disease caused by Treponema pallidum, with human beings as the only host. The combination of syphilis and squamous cell carcinoma of the skin is not uncommon, particularly if the lesions are located on different parts of the body. However, simultaneous development of the chancre and squamous cell carcinoma of the glans penis seems exceptional. Considering rarity of the manifestation observed we feel the rare case of combined syphilis and squamous cell skin cancer is of interest.
Vestnik dermatologii i venerologii. 2016;92(6):61-65
pages 61-65 views

Lepra recurrent developed after termination of antileprotic therapy

Kubanov A.A., Karamova A.E., Semenova V.G., Smoliannikova V.A., Nefedova M.A.

Abstract

Lepra is an infectious disease, granulomatosis caused by Mycobacterium leprae. It is characterized with prolonged latent period (from 3-5 years to several decades), low transmission, generally lesions of skin and peripheral nervous system. The recurrent of disease is possible after the termination of antileprotic therapy. A case report presented demonstrating the lepra recurrent in female patient 4 years after termination of therapy; that was conducted during 17 years and led to the regression of clinical symptoms and to negative results of bacterioscopic examination of nasal brushings and scratch samples from sites of former eruptions. This case should call attention of dermatologists and other physicians to the problem of leprosy recurrent diagnosis in previously observed and deregistered patients.
Vestnik dermatologii i venerologii. 2016;92(6):66-72
pages 66-72 views

CLINICAL PRACTICE GUIDELINES

Differential diagnostics of bullous dermatoses

Kubanov A.A., Znamenskaya L.F., Abramova T.V.

Abstract

Bullous dermatoses are the diseases characterized by vesication and erosion of skin and/or mucos coats, production of autoantibodies against the structural components of epidermis and/or derma. The most frequent diseases of these disorders are pemphigus, bullous pemphigoid, dermatitis herpetiformis, beningn familial chronic pemphigus (Gougerot Hailey-Hailey disease).Diagnostics of bullous dermatoses is based on assessement of clinical signs, results of cytological and histological studies and immunological tests. However none of the current diagnostic methods allows to reveal bullous dermatosis severally and with absolute certainty. Consequently it is necessary to perform wide range of clinical and laboratory tests for early diagnosis and treatment order.
Vestnik dermatologii i venerologii. 2016;92(6):43-56
pages 43-56 views

SHORT COMMUNICATION

Obesity related skin disorders

Gorlanov I.A., Zaslavskiy D.V., Leina L.M., Milyavskaya I.R.

Abstract

Obesity is a serious global problem. In recent years, it has been an increase in patients with obesity. In a review of literature presents data on the effect of obesity on the skin. It is responsible for the development of a number of dermatological diseases, including acantosis nigricans, akrohordony, follicular hyperkeratosis, infectious diseases of the skin. Against the background of obesity worsens psoriasis. The connection between obesity and atopic dermatitis.
Vestnik dermatologii i venerologii. 2016;92(6):20-26
pages 20-26 views

DRUG TREATMENT IN DERMATOVENEROLOGY

The complex therapy of acne rosacea with azelaic acid preparations

Gladko V.V., Masyukova S.A., Ilina I.V., Sanakoyeva E.G., Gorbakova E.V., Zemlyakova S.S.

Abstract

The present literature data on pathogenesis and treatment of acne rosacea are reported in the article. Research results on effectiveness of therapy with azelaic acid at patients with acne rosacea are presented. The nosotropically based standard of acne rosacea therapy is accepted in virtue of the world practice data.
Vestnik dermatologii i venerologii. 2016;92(6):73-78
pages 73-78 views

Analysis of methods common topical treatment of the generalized dermatoses in the delivery of the specialized health care in the profile "Dermatology"

Kokhan M.M., Samtsov A.V., Perlamutrov Y.N., Sokolovskiy E.V.

Abstract

Results of sampling epidemiological investigation of patients with dermatologic diseases, which sought treatment in the specialized Russian outpatient facilities over two-month period, and assessments of approaches to treatment of patients with atopic dermatitis, psoriasis and eczema are presented. Data of 2991 individual registration cards, which were filled out by the dermatovenerologists providing primary specialized care to patients in outpatient facilities of Perm, Samara and St. Petersburg, was analyzed. It was observed that women were prevalent among patients with dermatoses, and most of women and men were of working age (82.2 and 89.2% corresponding). The nosological structure of appealability consists of 25.6% patients with dermatose, psoriasis (14.5%), eczema (13.4%), seborrhea and acne (8.6%), atopic dermatitis (5.8%), and pyodermatitis (3.2%). Using standardized indexes for assessment it was discovered that among applied outpatients 80% persons, presented with atopic dermatitis, and 50% persons, presented with psoriasis, had moderate and severe appearances of dermatoses. In therapy of patients with atopic dermatitis, psoriasis and eczema, specialists used widely standard system treatment - topic glucocorticosteroid agents for external care.
Vestnik dermatologii i venerologii. 2016;92(6):79-93
pages 79-93 views

Efficacy of the combined therapy with etanercept and methotrexat at the female patient with generalized pustular psoriasis and arthritis psoriasis after the therapeutic failure of two the TNF-α receptor inhibitors. Case study

Vustina V.V., Grigoriadi N.E., Korotayeva T.V.

Abstract

The article presents the clinical observation effectiveness of TNF-a inhibitor etanercept in patients with generalized pustular psoriasis and PsA, resistant to treatment by other drugs of this class. It presents the current recommendations for the management of patients with pustular psoriasis.
Vestnik dermatologii i venerologii. 2016;92(6):94-100
pages 94-100 views

ORGANIZATION OF HEALTH CARE AND EPIDEMIOLOGY

On the new model of funding and quality assurance of dermatovenereologic care

Martynov A.A., Stadchenko N.N., Vlasova A.V.

Abstract

The article deals with modern approaches to organization of delivery and financial support of high-tech medical care on the profile of “dermatovenereology”, and with introduced mechanisms for quality assurance of medical care and independent evaluation of the services provided.
Vestnik dermatologii i venerologii. 2016;92(6):10-19
pages 10-19 views

HISTORICAL ARTICLE

On the 115th anniversary of the dermatovenereology department of the academician I.P. Pavlov First St. Petersburg state medical university (part I)

Krasnoselskikh T.V., Sokolovskiy E.V.

Abstract

The history of the Department of Dermatovenereology of the First St. Petersburg State Medical University from its foundation in 1901 till 1956 is traced in the article. These years of formation and development of the Department were associated with the activities of the outstanding dermatologists such as T.P. Pavlov, S.Ya. Kulnev, A.A. Sakhnovskaya, O.N. Podvysotskaya.
Vestnik dermatologii i venerologii. 2016;92(6):101-108
pages 101-108 views


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