Clinical efficacy, safety and tolerance of clindamycin phosphate gel, 1%, in the treatment of mild tomoderate acne



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Abstract

The authors present the results of a prospective, open-label, post-registration comparative study of the monotherapy
of mild to moderate acne with an inflammatory component. 30 subjects aged 15-35 were engaged in the study.
Subjects from Group 1 (n = 15) received Clindovit® in the form of 1% gel, and subjects from Group 2 (n = 15) received
a combination of erythromycin and zinc in the form of lotion. The duration of treatment and participation in the study
was 8 weeks. Dynamics of clinical manifestations of the disease, Dermatology Life Quality Index (DLQI), Psychological
and Social Effects of Acne (APSEA), frequency and severity of adverse events against the background of treatment
were assessed. The results of the study enabled the investigators to make a conclusion about efficacy, safety and good
tolerance of Clindovit® gel as a monotherapy of mild to moderate acne with an inflammatory component.

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Copyright (c) 2011 Samtsov A.V., Sukharev A.V., Bondar' O.I., Patrushev A.V., Nazarov R.N., Minchenko A.A., SAMTSOV A.V., SUKHAREV A.V., BONDAR O.I., PATRUSHEV A.V., NAZAROV R.N., MINCHENKO A.A.

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