Изучение генетических факторов предрасположенности к развитию псориаза



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Представлены данные литературы об эпидемиологии, патогенезе и генетике псориаза. Особое внимание уделено генетическим факторам предрасположенности к развитию псориаза. Проанализированы исследования, посвященные полногеномному скринингу ассоциаций полиморфных генетических локусов с развитием псориаза. Полученные результаты позволяют выявить патогенетические механизмы псориаза, прогнозировать характер клинического течения заболевания и эффективность терапии, а также прогнозировать риск появления псориаза у родственников больных.

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Изучение генетических факторов предрасположенности к развитию псориаза
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Об авторах

А А Минеева

ФГБУ «ГНЦДК» Минздравсоцразвития России

Email: derma-am@yandex.ru
м.н.с. отдела дерматологии Москва

О С Кожушная

ФГБУ «ГНЦДК» Минздравсоцразвития России

м.н.с. отделения молекулярных методов диагностики, отдела лабораторной диагностики ИППП и болезней кожи Москва

В А Волнухин

ФГБУ «ГНЦДК» Минздравсоцразвития России

д.м.н., проф., в.н.с. отделения по разработке физиотерапевтических методов лечения Москва

Н В Фриго

ФГБУ «ГНЦДК» Минздравсоцразвития России

д.м.н., зам. директора по научно-образовательной работе Москва

Л Ф Знаменская

ФГБУ «ГНЦДК» Минздравсоцразвития России

д.м.н., зав. отделом дерматологии Москва

А А Кубанов

ФГБУ «ГНЦДК» Минздравсоцразвития России

д.м.н., проф., зам. директора по научной работе Москва

Л Е Мелехина

ФГБУ «ГНЦДК» Минздравсоцразвития России

ст.н.с. научно-организационного отдела, группа эпидемиологии, ИППП и дерматозов Москва

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