Vol 87, No 4 (2011)

Uvazhaemye kollegi!
 
Abstract
Vestnik dermatologii i venerologii. 2011;87(4):4-5
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Prevalence of atopic dermatitis among children and teenagers in ural, siberian and far eastern federalregions
 
Abstract
The author presents an analysis of prevalence of atopic dermatitis among children at the age of 0-14 and teenagers at the age of 15-17 on the basis of data from official public statistical reports for the Russian Federation and for territories of Ural, Siberia and Far East for the period of 2005-2009.
Vestnik dermatologii i venerologii. 2011;87(4):8-13
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Genetic profile of psoriasis patients
 
Abstract
The article systematizes information about genetic polymorphisms associated with the risk of psoriasis and psoriatic arthritis development. Gene variants that are potentially essential for their inclusion in genetic tests were sampled taking into consideration polymorphism localization. The presented data are sufficient to prepare the genetic profile of psoriatic patients, forecast the clinical course of the disease and potential efficacy of treatment, and calculate the risk of the disease development in the patients relatives.
Vestnik dermatologii i venerologii. 2011;87(4):14-19
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Modern immunochromatographic methods for determination of anti-treponema pallidum antigenantibodies
 
Abstract
The authors present a review of research publications about clinical significance of using modern immunochromatographic methods for determination of anti-immunodominant antigen antibodies of syphilis pathogen Treponema pallidum. Immunochromatographic sets of chemicals proved to be convenient in use, can be used with a small amount of biological materials, do not demand any specialized medical equipment, have high sensitivity and specificity, in particular, for tests with blood serum or plasma samples; when whole blood samples are used, this reduces the method sensitivity. Immunochromatographic tests are intended for prompt express examination of the population to reveal syphilis patients under field conditions or at medical institutions consulting primary patients and not having their own clinical laboratories.
Vestnik dermatologii i venerologii. 2011;87(4):20-24
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Pro-inflammatory IL-1 and TNF alpha cytokines in affected skin foci in psoriatic patients
 
Abstract
The article presents the authors data related to an ongoing study of the expression of pro-inflammatory IL-1 and TNF alpha cytokines in affected skin foci in psoriatic patients. The authors revealed particular features related to the increased expression of IL-1 in the skin structures with absence of TNF alpha expression.
Vestnik dermatologii i venerologii. 2011;87(4):25-30
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Using SIAscopy to assess the intensity of pathologic changes in skin when melanocyticneoplasms develop
 
Abstract
The authors describe the use of spectrophotometry intracutaneous analysis method for the purposes of differential diagnostics of pigmented skin neoplasms.
Vestnik dermatologii i venerologii. 2011;87(4):31-36
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Etiology and clinical and epidemiological profile of erosive and ulcerative affections of genitals
 
Abstract
The authors present data on clinical characteristics of the course of erosive and ulcerative affections on the skin of genitals in patients who consulted a dermatovenerologist. The authors analyzed factors contributing to the onset of this pathology and having an effect on the severity of its course. They also studied the composition of microbial associations present in the discharge from lesion foci. The authors demonstrated the prevalence of a mixed infection as well as opportunistic microflora in most patients suffering from erosive and ulcerative affections on the skin of genitals.
Vestnik dermatologii i venerologii. 2011;87(4):37-45
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Treatment of vulvovaginites caused by opportunistic microorganisms. Current concepts and efficacyassessment
 
Abstract
The author describes current approaches to treatment of vulvovaginites caused by opportunistic microorganisms. The author assessed clinical and microbiological efficacy of different methods of treatment used for this pathology.
Vestnik dermatologii i venerologii. 2011;87(4):46-52
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Differential diagnostics of keloid and hypertrophic scar tissues based on differences in skinsensitivity
 
Abstract
A study of different types of skin sensitivity in patients with keloid and hypertrophic scar tissues was conducted in order to optimize clinical diagnostics of scar hypertrophy of the skin. A symmetrical area of unaffected skin was examined as control. The revealed results suggest a sharp increase of deep skin sensitivity with simultaneous reduction of other types of sensitivity, which was observed in 97% of subjects, as a new differential sign of keloid scar tissues.
Vestnik dermatologii i venerologii. 2011;87(4):53-55
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Experience of using ursodeoxycholic acid in complex treatment of patients suffering from atopicdermatitis
 
Abstract
The authors describe the results of a clinical study of 90 patients suffering from different clinical forms of atopic dermatitis (AD), who received hepatotropic drugs in combination with ursodeoxycholic acid. A misbalance of cellular and humoral immunity was revealed in these patients prior to the onset of treatment. The inclusion of ursodeoxycholic acid in complex treatment of AD contributed to normalization of immunity indices and regression of skin eruptions.
Vestnik dermatologii i venerologii. 2011;87(4):56-63
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Follicular vegetative dyskeratosis complicated with a secondary infection
 
Abstract
A patient with a rare form of dermatosis, follicular vegetative dyskeratosis (Darier-White disease), was under observation. Particular features of the case under examination are described: prevalent skin eruptions with affected mucous coats of the oral cavity; pathologic process complicated with a secondary infection. The efficacy of neotigason, a drug belonging to the group of synthetic retinoids, was demonstrated.
Vestnik dermatologii i venerologii. 2011;87(4):64-69
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Pseudo - kaposhi sarcoma (Mali type). Clinical case
 
Abstract
The paper presents the clinical case of Pseudosarcoma Kaposi (Mali type) of patient at age of 45 years. Its manifestation was induced by trauma and this was not a congenital vascular dysplasia as in Pseudo - Kaposhi sarcoma (Stewart - Bluefarb type).
Vestnik dermatologii i venerologii. 2011;87(4):70-72
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Family case of hystriciasis
 
Abstract
The authors describe a rare case of family hystriciasis in a mother aged 35 and her children (son aged 7 and daughter aged 4). A review of literature from Russian and foreign sources is given.
Vestnik dermatologii i venerologii. 2011;87(4):73-79
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Central centrifugal scarring alopecia as a rare form of scarring alopecia
 
Abstract
The authors describe a rare form of scarring alopecia - central centrifugal scarring alopecia (synonym: follicular degeneration syndrome). A particular feature of this disorder is a combination of scarring alopecia with pathology of the thyroid gland. The authors also provide a classification of primary scarring alopecias.
Vestnik dermatologii i venerologii. 2011;87(4):80-83
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Assessment of the efficacy of antihistamine drugs in complex treatment of chronic itchingdermatoses
 
Abstract
The authors give a review of current concepts of mechanisms of skin itching development for different types of chronic dermatoses. The authors also present the results of a study aimed at assessing the efficacy of different 2nd generation antihistamine drugs used for complex treatment of 83 patients aged 14-73 suffering from different chronic itching dermatoses (atopic dermatitis, eczema, pruritus, chronic urticaria, progressing psoriasis, lichen acuminatus, contact allergic dermatitis). The authors conclude that Glencet (levocetirizine) used in a complex therapy of dermatoses accompanied with itching can efficiently arrest both subjective itching sensations and objective clinical symptoms of the diseases as well as reliably (р < 0.001) reduce the term of inpatient care by 4.8 ± 2.3 on average. Glencet (levocetirizine) is a drug of choice among the 2nd generation antihistamine drugs used for treatment of chronic skin diseases accompanied with itching.
Vestnik dermatologii i venerologii. 2011;87(4):84-87
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Current approaches to the external therapy of photodermatoses
 
Abstract
Remedial measures for photodamages of skin are mainly aimed at elimination of inflammation and subjective sensations such as burning and itching. Topical corticosteroids remain leading drugs in the external therapy of phototrauma, phototoxic and photoallergic reactions. Mometasone furoate (Elocom) has high anti-inflammatory and antiallergic activity. Moreover, the composition of the Elocom cream is based on titanium dioxide, a classical mineral screen, which makes it possible to use the Elocom cream in case of steroid-sensitive pathology under conditions of high solar exposure. The Elocom cream has been used in the monotherapy and complex treatment of solar dermatitis, actinic cheilitis, polymorphous light eruption, discoid lupus erythematosus and actinic prurigo. Regression of manifestations of solar dermatitis was recorded on Day 1-3 of treatment, and regression of manifestations of actinic cheilitis - during Week 2 of treatment. The process in case of photoallergic reactions and discoid lupus erythematosus was over during Week 3-4 of treatment. Substances making a part of the composition of the Elocom cream and having photoprotective properties make this cream a drug of choice for its use on skin areas subject to solar exposure in case of steroidsensitive pathology including phototrauma, phototoxic and photoallergic reactions. Besides, photoprotective properties of the Elocom cream explain why it should be selected for treatment of steroid-sensitive dermatoses becoming more severe or appearing after solar exposure, in case of localization of eruptions on open skin areas (face, neck, decollete area, hands, etc.)
Vestnik dermatologii i venerologii. 2011;87(4):88-95
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Metody korrektsii narusheniy kozhnogo bar'era pri pomoshchikosmeticheskikh sredstv Emolium u beremennykh, bol'nykhatopicheskim dermatitom
 
Abstract
Results of examination of the skin barrier in 57 pregnant women with atopic dermatitis and 48 dermatologically healthy pregnant women are presented. In the majority of patients with atopic dermatitis significant disorders of the skin barriers have been found out both within the lesions and on clinically normal skin. More than a quarter of dermatologically healthy pregnants demonstrated the lack of skin barriers on the dorsal surface of the hands. Use of complex emollients (gamma «Emolium») improved characteristics of skin barrier permeability among the individuals with atopic dermatitis.
Vestnik dermatologii i venerologii. 2011;87(4):97-100
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Methods to improve the efficacy of treatment of inflammatory diseases of small pelvic organsassociated with a mycoplasma infection
 
Abstract
The authors present the results of examination and treatment of 40 female patients with recurrent urogenital infections, who had optional and/or obligate anaerobes revealed by bacteriological tests (patients were withdrawn from the study if Neisseria gonorrhoeae, C. trachomatis, Treponema pallidum or Trichomonas vaginalis were revealed). The patients received treatment with doxycycline or josamycin depending on the results of determination of sensitivity of cultivated microorganisms. Evident positive dynamics of clinical manifestations was recorded as a result of use of these drugs. Normalization of biocenosis and absence of opportunistic flora were recorded for 38 patients.
Vestnik dermatologii i venerologii. 2011;87(4):102-106
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Lavomax - new potential of the complex therapy of genital herpes
 
Abstract
The goal of this study was to assess clinical efficacy and safety of Lavomax and to provide pathogenetic grounds for its use in the complex therapy of patients suffering from genital herpes. The study subjects were 64 patients suffering from genital herpes. Their diagnosis was verified on the basis of ELISA and PCR results. Immunoassays revealed various disorders of immune homeostasis and natural resistance. These results confirm that there are pathogenetic grounds to use Lavomax in the complex therapy of genital herpes. Complex treatment with the use of Lavomax normalizes immune homeostasis and quickly reduces clinical manifestations of herpes significantly reducing the frequency and duration of recurrences of the disease.
Vestnik dermatologii i venerologii. 2011;87(4):108-110
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Mixed urogenital infections: clinical and therapeutic approaches
 
Abstract
The authors present the results of a study involving 80 patients suffering from inflammatory diseases of the urogenital system caused by mixed pathogenic and opportunistic urinogenital infection. The patients underwent clinical and laboratory examination; clinical characteristics of the course of the disease were recorded. The study results demonstrated clinical and microbiological efficacy of Safocid, a combined drug used for treatment of this group of patients.
Vestnik dermatologii i venerologii. 2011;87(4):112-116
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Xerosis and xemose
 
Abstract
This article covers current concepts of the barrier function of skin, major pathophysiological mechanisms of skin xerosis development, its fillagrin-dependent mutations and major clinical signs by the example of atopic dermatitis. The author gives recommendations for using moisturizers on the basis of Uriage Thermal Water comprising Xemose Cream, Xemose Cerate and Xemose Gel-Cream for efficient reduction of extra skin dryness.
Vestnik dermatologii i venerologii. 2011;87(4):121-124
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Conference of dermatovenerologists and cosmetologists from the Siberian Federal Region
 
Abstract
Vestnik dermatologii i venerologii. 2011;87(4):126-127
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