Early onset of mycosis fungoides. Case from practice

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Abstract

Clinical and morphological heterogeneity of malignant lymphoproliferative lesions of the skin is explained by the peculiarities of their pathogenesis and organization of the lymphoid tissue in the skin. These features determine the authenticity of therapeutic approaches to patients with this pathology and exclude the use of standard regimens of polychemotherapy used in oncology due to their low efficacy. The authors describe a case study of a suberythrodermic form of mycosis fungoides in a 16-year-old female patient.

About the authors

D. V. Zaslavsky

St. Petersburg State Pediatric Medical University

Author for correspondence.
Email: venereology@gmail.com
Russian Federation

A. A. Sidikov

St. Petersburg State Pediatric Medical University

Email: venereology@gmail.com
Russian Federation

L. N. Drozdova

St. Petersburg State Pediatric Medical University

Email: venereology@gmail.com
Russian Federation

O. K. Mineeva

St. Petersburg State Pediatric Medical University

Email: venereology@gmail.com
Russian Federation

I. N. Chuprov

I.I. Mechnikov North-Western State Medical University

Email: venereology@gmail.com
Russian Federation

Wolkenstein Pierre

Hopitaux Universitaires Henri Mondor

Email: venereology@gmail.com
Russian Federation

S. V. Skrek

I.I. Mechnikov North-Western State Medical University

Email: venereology@gmail.com
Russian Federation

References

  1. Nashan D., Faulhaber D., Stander S., Luger T.A., Stadler R. Mycosis fungoides a dermatological masquerader. Br J Dermatol. 2007; 156: 1-10.
  2. Hinds G.A., Heald P. Cutaneous T-cell lymphoma in skin of colour. J Am Dermatol. 2009; 60: 359-375.
  3. Willemze R., Meijer C.J. Classification of cutaneous T-cell lymphoma: from Alibert to WHO-EORTC. J Cutan Pathol 2006; 33: 18-26.
  4. Jukov A.C., Belousova I.E., Samtcov A.V. The role immunohistochemistry in mycosis fungoides.Vestnik Dermatologii I Venerologii 2014; (2): 38-46
  5. Grange F., Bagot M. Pronostic des lymphomes cutanés primitifs. AD-01-2002-129-1-0151-9638-101019-ART7
  6. Delfau-Larue M.H., Dalac S., Lepage E. et al. Prognostic significance of a polymerase chain reaction-detectable dominant T-lymphocyte clone in cutaneous lesions of patients with mycosis fungoides. Blood, 1998, 92: 3376-3380.

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Copyright (c) 2015 Zaslavsky D.V., Sidikov A.A., Drozdova L.N., Mineeva O.K., Chuprov I.N., Pierre W., Skrek S.V.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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