Topical therapy for facial allergic dermatoses

Cover Page

Cite item


The research goal is to assess clinical dynamics and morphofunctional skin parameters of patients with facial allergic dermatoses on the background of combined topical therapy. Materials and methods. 45 patients with various facial allergic dermatoses in dry and sensitive skin took part in the research. The methods included anamnesis taking, poll, objective examination and assessment of morphofunctional parameters of skin, as well as estimation of life quality dynamic index (LQDI). Main results. After a course of treatment with 0,05% solution of alclometasone dipropionate inflammation of dermatosis ceased in 45 (100%) patients, itching and pains in 39 (86,7%) patients, but complaints about dryness and peeling of facial skin remained in 41 (91,1%) and 40 (88,8%) patients respectively. On the background of therapy including emollient Aflocream the above mentioned symptoms did not appear in 43 (95,6%) patients, wherein maximum effect was achieved in patients with allergic contact dermatitis - 14 (93,3%). After a course of topical therapy all patients showed statistically significant increase of epidermal moisture level, alongside with reduction of skin relief and degree of keratinization. During the assessment of LQDI a tendency to reduction of proportion of patients on whom the disease has a strong and extremely strong impact was noted in 10 patients (i.e. 22,2%), moderate influence - in 5 of them (11,45%), insignificant influence or its absence - in 30 (66,7%) people. Conclusion. Combined therapy including the use of a topical corticosteroid Afloderm and an emollient Aflocream showed good clinical efficiency in patients with facial allergic dermatoses. The efficiency is also confirmed with improvements in morphofunctional characteristics of patients’ skin on the background of therapy.

About the authors

Y. S. Kondratyeva

Altai Medical State University

Author for correspondence.
Russian Federation

T. N. Shepileva

Altai Medical State University

Russian Federation

E. A. Subbotin

Altai Medical State University

Russian Federation


  1. Rodionov A.N. Dermatokosmetologiya. Porazheniya kozhi litsa i slizistykh. Diagnostika, lechenie i profilaktika. SPb.: Nauka i tekhnika; 2012. [Родионов А.Н. Дерматокосметология. Поражения кожи лица и слизистых. Диагностика, лечение и профилактика. СПб: Наука и техника 2012.]
  2. Rutsika T., Tsaumzel' R.P. Effektivnost' i perenosimost' metilprednizolona atseponata (“Advantana”) pri lechenii allergicheskikh dermatozov s porazheniem litsa. Clin Dermatol Venerol 2003; (2): 68-73. [Руцика Т., Цаумзель Р.П. Эффективность и переносимость метилпреднизолона ацепоната («Адвантана») при лечении аллергических дерматозов с поражением лица. Клин дерматол венерол 2003; (2): 68-73.]
  3. Belousovа T.A. Modern approaches to topical treatment of allergic dermatosis. Materia Medica 2002; (3): 60-73. [Белоусова Т.А. Современные подходы к наружной терапии аллергодерматозов. Materia Medica 2002; (3): 60-73.]
  4. Kochergin N.G., Belousovа Т.А. On the issue of local corticosteroid therapy. Russian Journal of Skin and Venereal Disieases 2001; (2): 28-31. [Кочергин Н.Г., Белоусова Т.А. К вопросу о местной кортикостероидной терапии. Рос журн кож вен бол 2001; (2): 28-31.]
  5. Kathanova O.A. The efficacy of application of the skin-care cosmetic products in the children suffering from allergic dermatoses. Clin Dermatol Venerol 2012; (2): 61-65. [Катханова О.А. Эффективность применения лечебной косметики у детей с аллергическими дерматозами. Клин дерматол венерол 2012; (2): 61-65.]
  6. Petrova G.A. Printsipy naruzhnoy kortikosteroidnoy terapii allergodermatozov. Current Pediatrics 2005; (5): 92-94. [Петрова Г.А. Принципы наружной кортикостероидной терапии аллергодерматозов. Вопр соврем педиатр 2005; (5): 92-94.]
  7. Belousova T.A., Goryachkna M.V. Mesto naruzhnoy kortikosteroidnoy terapii v praktike vrachadermatologa. Consilium medicum. Dermatology 2008; (1): 3-6. [Белоусова Т.А., Горячкна М.В. Место наружной кортикостероидной терапии в практике врача-дерматолога. Consilium medicum. Дерматология 2008; (1): 3-6.]
  8. Tamrazova O.B., Kuznetsova O.A. Emolenty: berezhnoe lechenie i sovremennyy ukhod za kozhey u detey, stradayushchikh atopicheskim dermatitom. Consilium Medicum. Pediatrics 2013; (1): 65-71. [Тамразова О.Б., Кузнецова О.А. Эмолиенты: бережное лечение и современный уход за кожей у детей, страдающих атопическим дерматитом. Consilium Medicum. Педиатрия 2013; (1): 65-71.]
  9. Belousova T.A, Goryachkina M.V.Jherapeutic possibilities for the correction of damages of dry skin barrier features. Vestn Dermatol Venerol 2012; (3): 128-133. [Белоусова Т.А., Горячкина М.В. Терапевтические возможности коррекции нарушений барьерных свойств сухой кожи. Вестн дерматол венерол 2012; (3): 128-133.]
  10. Marks R. Actions and effects of emollients. In: Sophisticated Emollients. Georg ThiemeVerlag, Stuttgart, New York, 2002: 12-23.
  11. Trapp M. Is there room for improvement in the emollients for adjuvant therapy? J Eur Acad Dermatol Venereol 2007; 21 (2): 14-18.

Copyright (c) 2015 Kondratyeva Y.S., Shepileva T.N., Subbotin E.A.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 60448 от 30.12.2014.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies