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Skin lesion at acute monoblastic leukemia (clinical observation)
- Authors: Chernova N.G.1, Sinicyna M.N.1, Dvirnyk V.N.1, Kovrigina A.M.1, Zvonkov E.E.1, Parovichnikova E.N.1
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Affiliations:
- Hematological Scientific Center
- Issue: Vol 93, No 1 (2017)
- Pages: 46-50
- Section: CLINICAL CASES
- URL: https://vestnikdv.ru/jour/article/view/296
- DOI: https://doi.org/10.25208/0042-4609-2017-93-1-46-50
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Abstract
At present diagnosis of acute leukemia does not represent any difficulties and is based on morphological and immunophenotypical bone marrow studies. The paper presents a non-standard verification algorithm of acute monoblastic leukemia in elderly female patient, with leukemic skin lesion. Morphologic and immunohistochemical studies of biopsy materials of skin, lymph node and bone marrow allow establishing a linear membership of tumor cells and promptly verifying the diagnosis of leukemia. Lack of the overall clinical examination in such cases leads to diagnostic errors and to late verification of the true diagnosis and significantly worsens the prognosis.
About the authors
N. G. Chernova
Hematological Scientific Center
Author for correspondence.
Email: ngchernova@mail.ru
Russian Federation
M. N. Sinicyna
Hematological Scientific Center
Email: noemail@neicon.ru
Russian Federation
V. N. Dvirnyk
Hematological Scientific Center
Email: noemail@neicon.ru
Russian Federation
A. M. Kovrigina
Hematological Scientific Center
Email: noemail@neicon.ru
Russian Federation
E. E. Zvonkov
Hematological Scientific Center
Email: noemail@neicon.ru
Russian Federation
E. N. Parovichnikova
Hematological Scientific Center
Email: noemail@neicon.ru
Russian Federation
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