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Particular features of angiogenesis in lesions in patients suffering from basal cell epithelioma
- Authors: Khlebnikova A.N.1, Novoselova N.V.1
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Affiliations:
- ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России
- Issue: Vol 90, No 3 (2014)
- Pages: 60-64
- Section: ORIGINAL STUDIES
- URL: https://vestnikdv.ru/jour/article/view/33
- DOI: https://doi.org/10.25208/0042-4609-2014-90-3-60-64
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Abstract
Basal cell epithelioma is one of the most frequent malignant skin neoplasms. Angiogenesis plays an important part in the development of basal cell epithelioma. The article presents a review of the angiogenesis of this tumor with the help the immunohistochemistry analysis using CD31 and CD34 markers. The authors established a reliable relationship between the number of vessels expressing CD31 and those expressing CD34 in the superficial and nodular forms of the tumor as well as superficial, multi-center, nodular and infiltrative basal cell epitheliomas. A comparison of the number of vessels expressing CD31 and CD34 markers in different histological types made revealed a trend to their growth in the infiltrative type vs. superficial, multi-center and nodular ones.
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About the authors
A. N. Khlebnikova
ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
N. V. Novoselova
ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России
Email: noemail@neicon.ru
Russian Federation
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).