Particular features of angiogenesis in lesions in patients suffering from basal cell epithelioma

Cover Page


Cite item

Full Text

Abstract

Basal cell epithelioma is one of the most frequent malignant skin neoplasms. Angiogenesis plays an important part in the development of basal cell epithelioma. The article presents a review of the angiogenesis of this tumor with the help the immunohistochemistry analysis using CD31 and CD34 markers. The authors established a reliable relationship between the number of vessels expressing CD31 and those expressing CD34 in the superficial and nodular forms of the tumor as well as superficial, multi-center, nodular and infiltrative basal cell epitheliomas. A comparison of the number of vessels expressing CD31 and CD34 markers in different histological types made revealed a trend to their growth in the infiltrative type vs. superficial, multi-center and nodular ones.

About the authors

A. N. Khlebnikova

ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России

Author for correspondence.
Email: noemail@neicon.ru
Россия

N. V. Novoselova

ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России

Email: noemail@neicon.ru
Россия

References

  1. Galil-Agly G.A., Molochkov V.A., Sergeev Ju.V. Dermatoonkologija. M, 2005; 334-340.
  2. Neil Crowson Basal cell carcinoma: biology, morphology and clinical implications. Modern pathology 2006, 19, P. 127-147.
  3. Snarskaja E.S., Molochkov V.A. Bazalioma. M, 2003; 324.
  4. Cernea C.R., Ferraz A.R., de Castro I.V. Angiogenesis and skin carcinomas with skull base invasion a case-control study. Head Neck 2004; 26: 5: 396-400.
  5. Ahundov Je.D., Muradov H.K., Alieva I.O., Sadyhova G.G. Immunogistohimicheskie issledovanija angiogeneza pri sarkome Juinga. Hirurgija 2011; 11: 41-44.
  6. Babichenko I.I., Kovjazin V.A. Novye metody immunogistohimicheskoj diagnostiki opuholevogo rosta: Ucheb. posobie. M: RUDN 2008; 109.
  7. Chuprov I.N. Kliniko-morfologicheskaja harakteristika raznyh tipov bazal'nokletochnogo raka kozhi. Vestnik Sankt-Peterburgskogo universiteta 2009; 1: 145- 150.
  8. Abdyeva S.V. Jekspressija SD31 v plejomorfnom variante zlokachestvennoj fibroznoj gistiocitomy mjagkih tkanej. Onkologija 2011; 2: 122-124.
  9. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. NatMed 1995; 1 (1): 27-31.
  10. Aslani F., Aledavood A. Angiogenesis assessment in basal cell carcinoma. Medical Joumal of the Islamic Republic of Iran 2001; 8: 15-2.
  11. Buzina R.V. Zavisimost' vyrazhennosti angiogeneza ot nalichija i rasprostranennosti jepitelial'nomezenhimal'noj transformacii v rake zheludka. Novoutvorennja 2011; 2: 81.
  12. Kubanova A.A., Smol'jannikova V.A., Stepanova E.V., Balabaev D.A. Immunogistohimicheskaja harakteristika angiogeneza razlichnyh morfologicheskih form bazal'no-kletochnogo raka kozhi. Tezisy Vserossijskogo kongressa dermatovenerologov. S-Pb, 2007.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2014 Khlebnikova A.N., Novoselova N.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 60448 от 30.12.2014.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies