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Current approaches to the treatment of vulvovaginitis caused by opportunistic microorganisms taking into consideration the antibacterial resistance of infectious agents
- Authors: Rakhmatulina MR1
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Affiliations:
- State Research Center of Dermatovenereology and Cosmetology, Ministry of Health Care of the Russian Federation
- Issue: Vol 89, No 2 (2013)
- Pages: 44-52
- Section: Articles
- URL: https://vestnikdv.ru/jour/article/view/565
- DOI: https://doi.org/10.25208/vdv565
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Abstract
Goal of the study. To study the qualitative and quantitative composition of the vaginal microcenosis in women of childbearing potential with vulvovaginitis and determine the sensitivity indices of opportunistic microorganisms being etiological agents of vulvovaginitis concerning antibacterial drugs. Materials and methods. Samples of the vaginal fluid obtained from 264 women (198 patients with clinical and laboratory signs of vulvovaginitis and 66 clinically healthy women) as well as 190 isolates of opportunistic microbial agents were analyzed with the use of microscopic and cultural methods as well as polymerase chain reaction. Results. The authors determined the composition of the vaginal microbiocenosis in women suffering from vulvovaginitis characterized by the prevalence of Corynebacterium spp., E. coli, E. faecalis, S. saprophiticus, K. pneumoniae, S. anginosus, S. agalactiae in the amount exceeding 10 2—10 4 CFU/ml and in associations of four or more microorganisms. The authors revealed that opportunistic microorganisms had the highest sensitivity to amoxicillin/clavulanic acid, nitrofuran and ceftriaxone.
Full Text
Современные подходы к терапии вульвовагинитов, вызванных условно-патогенными микроорганизмами, с учетом антибактериальной резистентности инфекционных агентов×
About the authors
M R Rakhmatulina
State Research Center of Dermatovenereology and Cosmetology, Ministry of Health Care of the Russian Federation
Email: rahmatulina@cnikvi.ru
Korolenko str. 3, bldg 6, 107076, Moscow, Russia
References
- Ankirskaya A.S., Murav'eva V.V. Infektsii vlagalishcha: laboratornaya diagnostika opportunisticheskikh infektsiy vlagalishcha. Consilium medicum 2005; 7(3): 44—47.
- Voropaeva E.A., Afanas'ev S.S., Kudrjavceva M.V. i dr. Mikrojekologija i pokazateli gumoral'nogo immuniteta vlagalishha zhenshhin s nespecificheskimi vospalitel'nymi zabolevanijami genitalij. Mikrobiologija 2005; (3): 65—69.
- Makarov O.V., Aleshkin V.A., Savchenko T.N. Infektsii v akusherstve i ginekologii. Moskva: Medpress-inform, 2007.
- Tikhomirov A.L., Oleynik Ch.G. Infektsii vlagalishcha: vzglyad ginekologa. Ratsional'naya terapiya kandidoznogo i smeshannykh vul'vovaginitov. Concilium Medicum 2005; 7(3): 40—42.
- Fofanova I.Yu. Rol' genital'noy uslovno-patogennoy mikroflory v akusherstve i ginekologii. Ginekologiya 2008;(2): 52—58.
- Bashmakova M.A., Savicheva A.M. Laboratornaya diagnostika genital'nykh infektsiy. Problemy reproduktsii 2000 (1): 20—24.
- Voropaeva S.D. Mikroflora zhenskikh polovykh putey i ee chuvstvitel'nost' k antibakterial'nym preparatam. Antibiotiki i khimioterapiya 1999 (3): 42—45.
- Serov V.N. Ratsional'naya terapiya vlagalishchnoy infektsii. Ginekologiya 2005; 7(2): 115—118.
- Uvarova E.V., Sultanova F.Sh. Vlagalishche kak mikroekosistema v norme i pri vospalitel'nykh protsessakh genitaliy razlichnoy etiologii (obzor literatury). Ginekologiya 2003; 4(4): 189—195.
- American Academy of Pediatrics. Group A streptococcal infections. Pickering L.K., ed. Red Book: Report of the Committee of Infectious Diseases, 25th eds. Elk Grove Village, IL: American Academy of Pediatrics 2000; 526—536.
- Аmsel R., Totten P. A. et al. Nonspecific vaginitis: diagnostic criteria and microbial and epidemiological associations. Am J Med 1983; 14: 74.
- Gerasimova N.M. Osobennosti diagnostiki aerobnogo vaginita. Sibir. zh. dermatol. i venerol. 2004 (5): 74—78.
- Kafarskaya L.I., Korshunova O.V., Efimov B.A. i dr. Mikrobnaya ekologiya vlagalishcha. Mikrobiologiya 2002 (6): 91—99.
- Kahlmeter G. An International Survey of the Antimicrobial Susceptibility of pathogens from Uncomplicated Urinary Tract Infections: the ECO-SENS. Project. J. Antimicrob. Chemother. 2003; 51(1): 69—76.
- Karlowsky J.A., Kelly L.J., Thornsberry C. et al. Trends in antimicrobial resistance among urinary tract infection isolates of Escherichia coli from female outpatients in the United States. Antimicrob. Agents. Chemother. 2002 (46): 2540—2545.
- Karpov O.I. Flemoklav Solyutab — novaya lekarstvennaya forma amoksitsillina/klavulanata v lechenii sinusita. Klinicheskaya farmakologiya i terapiya 2006; 15(4): 1—4.
- Cedillo-Ramires L. Association of Mycoplasma hominis and Ureaplasma urealyticum with some indicators of nonspecific vaginitis. Rev Latinoam Microbiol 2000; 42(1): 1—6.
- Klinicheskie rekomendatsii. Vedenie bol'nykh s infektsiyami, peredavaemymi polovym putemi urogenital'nymi infektsiyami. M., Delovoy Ekspress 2012; 112.
