Demodex mites and Malassezia yeast at patients with seborrheic dermatitis

Abstract

Target. Studies of dynamics of species diversity and of abundance of Malassezia fungi, аs well as of pimple mites at the skin of patients, suffering from seborrheic dermatitis (SD) at the treatment with activated zinc pyrithione aerosol (ZPA). Маterial and methods. 60 patients with SD were examined. 2 groups were segregated: 1-st (n = 31) - patients with SD, receiving within 4 weeks the AZP therapy; 2-nd (n = 29) - patients with SD, not receiving local therapy. At the examination the gravity of symptoms, the dynamics of skin integument affection was assessed, the mycological skin analysis for Malassezia fungi, as well as the acarological analysis for Demodex mites was performed. Results. 4 kinds of Malassezia were revealed on the skin of patients, suffering with SD disease, with dominating M. globosa (10 7 КОЕ/cm 2). At patients, suffering with SD, 2 kinds of mites were revealed: Demodex: D. brevis and D. folliculorum. D. Brevis was dominating - 65%, D.folliculorum - 26%. After affected sites of the facer skin of patients, suffering from SD, with AZP aerosol within 4 weeks was revealed the statically authentic decrease at the average by a factor of 2 from the number of Malassezia yeast, and the decrease (to 16%) of the frequency of D.brevis reveal, аs well as the complete elimination of D.folliculorum. After the course of therapy with topical AZP aerosol is over the high therapeutic effect is revealed at 90% patients with SD. Opinion. So, AZP aerosol can be recommend to the decrease of the number of Malassezia fungi at Demodex mites at the facial skin of patients, suffering with SD.

Full Text

Клещи рода Demodex и дрожжи рода Malassezia у пациентов с себорейным дерматитом
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References

  1. Tchernev G. Folliculitis et perifolliculitis capitis abscedens et suffodiens controlled with a combination therapy: Systemic antibiosis (Metronidazole Plus Clindamycin), dermatosurgical approach, and high-dose isotretinoin. Indian Journal of Dermatology 2011; 56 (3): 318-320.
  2. Потекаев Н.Н. Розацеа. М.: Бином; 2000.
  3. Forton F, Seys B, Marchal JL, Song AM Demodex folliculorum and topical treatment: acaricidal action evaluated by standardized skin surface biopsy. Br J Dermatol. 1998; 138(3): 461-466.
  4. Верхогляд И.В. Современная антипаразитарная терапия демодикоза. Клин. дерматол. венерол. 2006; (4): 89-91.
  5. Батыршина С.В., Гордеева А.М., Богданова М.А. и др. Эффективность геля скинорен в наружной терапии больных угревой болезнью и розацеа. Вестн. дерматол. венерол. 2005; (4): 25-28.
  6. Давыдова И.Б., Чхатвал Н.А., Королева М.А. Местное применение метронидазола в терапии акне и акнеиформных дерматозов. Клин. дерматол. венерол. 2008; (5): 73-75.
  7. Li J., O'Reilly N., Sheha H. et al. Correlation between Ocular Demodex Infestation and Serum Immunoreactivity to Bacillus Proteins in Patients with Facial Rosacea. Ophthalmology 2010; 117(5): 870-877.
  8. Мокроносова М. А., Глушакова А. М., Голышева Е. В. Обоснование отсутствия синдрома отмены препарата скин-кап: антимикотическая активность цинка пиритиона. Клин. дерматол. венерол. 2008; (5): 69-72.
  9. Полеско И.В., Осипов Г.А., Кабаева Т.И. Микроэкология организма человека при себорее и акне. Детские инфекции. 2006; 5 (3): 26-33.
  10. Бабьева И.П., Чернов И.Ю. Биология дрожжей. М.: Товарищество научных изданий КМК; 2004.
  11. Петрова-Никитина А.Д., Антропова А.Б., Биланенко Е.Н. и др. Динамика численности клещей семейства Pyroglyphidae и микромицетов в лабораторных культурах. Зоол. журн. 2011; 90 (1): 13-23.

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Copyright (c) 2012 MOKRONOSOVA M.A., GLUSHAKOVA A.M., GOLYSHEVA E.V., ZHELTIKOVA T.M.

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